Zobrazeno 1 - 10
of 707
pro vyhledávání: '"BMP9"'
Autor:
Yuanxiang Chen, Shiyu Yang, Tao Yu, Tao Zeng, Lan Wei, Yiqing You, Jiafeng Tang, Tingting Dang, Haoli Sun, Yan Zhang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Recent studies have found that histone-modified genes play an increasingly important role in tumor progression. Lysine(K) specific demethylase 4A (KDM4A) is a histone lysine-specific demethylase highly expressed in a variety of ma
Externí odkaz:
https://doaj.org/article/141213a00da64bdd99d93f4dce6a94f9
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Hepatic alveolar echinococcosis is a zoonotic disease with a high incidence in western China, particularly affecting plateau areas such as Qinghai, Tibet, and Xinjiang. Research has indicated the presence of neovascularization in the peripheral infil
Externí odkaz:
https://doaj.org/article/6d995545739041a0828b5e672777b9d3
Autor:
Mohammad Al Tarrass, Lucid Belmudes, Dzenis Koça, Valentin Azemard, Hequn Liu, Tala Al Tabosh, Delphine Ciais, Agnès Desroches-Castan, Christophe Battail, Yohann Couté, Claire Bouvard, Sabine Bailly
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background BMP9 and BMP10 are two major regulators of vascular homeostasis. These two ligands bind with high affinity to the endothelial type I kinase receptor ALK1, together with a type II receptor, leading to the direct phosphorylation of
Externí odkaz:
https://doaj.org/article/5764a562c7064ed688fbad16999dd25c
Autor:
Jie Zhang, Jinhai Jiang, Hang Liu, Shiyu Wang, Kaixin Ke, Siyuan Liu, Yue Jiang, Lu Liu, Xiang Gao, Baicheng He, Yuxi Su
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 101075- (2024)
Bone defects and non-union are prevalent in clinical orthopedy, and the outcomes of current treatments are often suboptimal. Bone tissue engineering offers a promising approach to treating these conditions effectively. Bone morphogenetic protein 9 (B
Externí odkaz:
https://doaj.org/article/3b60a618d69b4890ad11935b3c1feda7
Autor:
Claudia Siverino, Shorouk Fahmy-Garcia, Viktoria Niklaus, Nicole Kops, Laura Dolcini, Massimiliano Maraglino Misciagna, Yanto Ridwan, Eric Farrell, Gerjo J.V.M. van Osch, Joachim Nickel
Publikováno v:
Bioactive Materials, Vol 29, Iss , Pp 241-250 (2023)
Bone Morphogenetic proteins (BMPs) like BMP2 and BMP7 have shown great potential in the treatment of severe bone defects. In recent in vitro studies, BMP9 revealed the highest osteogenic potential compared to other BMPs, possibly due to its unique si
Externí odkaz:
https://doaj.org/article/45dfb93b0ed2401c8fd6e92803bdb4e3
Unveiling the Impact of BMP9 in Liver Diseases: Insights into Pathogenesis and Therapeutic Potential
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1013 (2024)
Bone morphogenetic proteins (BMPs) are a group of growth factors belonging to the transforming growth factor β(TGF-β) family. While initially recognized for their role in bone formation, BMPs have emerged as significant players in liver diseases. A
Externí odkaz:
https://doaj.org/article/3919f0f621e843b6b8b9a61e7ceaaaf8
Publikováno v:
BMC Molecular and Cell Biology, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background Bone morphogenetic protein 9 (BMP9) has been shown to regulate processes such as angiogenesis, endothelial dysfunction, and tumorigenesis. However, the role of BMP9 in preeclampsia (PE) is unclear. The purpose of this study was to
Externí odkaz:
https://doaj.org/article/51e4902c7ca74c8fa131617271c1aeaf
Autor:
Chengcheng Du, Qiang Cheng, Piao Zhao, Claire Wang, Zhenglin Zhu, Xiangdong Wu, Shengqiang Gao, Bowen Chen, Jing Zou, Wei Huang, Junyi Liao
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 1040-1054 (2023)
BMP9 mediated osteogenic differentiation mechanisms of MSCs were widely explored, however, mechanisms of BMP9-induced angiogenesis still need to be clarified. We previously characterized that Notch1 promoted BMP9-induced osteogenesis–angiogenesis c
Externí odkaz:
https://doaj.org/article/a444a42bbfdc4915bdf9ef2342b9f7a2
Autor:
Yuxin Zhang, Wenping Luo, Liwen Zheng, Jing Hu, Li Nie, Huan Zeng, Xi Tan, Yucan Jiang, Yeming Li, Tianyu Zhao, Zhuohui Yang, Tong-Chuan He, Hongmei Zhang
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background BMP9-stimulated DPSCs, SCAPs and PDLSCs are effective candidates for repairing maxillofacial bone defects in tissue engineering, while the most suitable seed cell source among these three hDMSCs and the optimal combination of most
Externí odkaz:
https://doaj.org/article/608bab53f59d4da0aaac9e8f715bb35a
Publikováno v:
Genes and Diseases, Vol 9, Iss 6, Pp 1566-1578 (2022)
Inflammation is a protective response of the body to pathogens and injury. Hence, it is particularly important to explore the pathogenesis and key regulatory factors of inflammation. BMP9 is a unique member of the BMP family, which is widely known fo
Externí odkaz:
https://doaj.org/article/4683e07445d54eca96f399091807c098