Zobrazeno 1 - 10
of 2 486
pro vyhledávání: '"BMP4"'
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106654- (2024)
Microphthalmia, mostly an autosomal dominant disorder, is a worldwide severe congenital ocular malformation that causes visual impairment. Our investigation unveiled a total of 30 genes associated with microphthalmia. Employing the CytoHubba and PPI
Externí odkaz:
https://doaj.org/article/5863910e798a4fb192ccc45ec74bb133
Autor:
Youngmin Hwang, Yuko Shimamura, Junichi Tanaka, Akihiro Miura, Anri Sawada, Hemanta Sarmah, Dai Shimizu, Yuri Kondo, Hyeonjeong Lee, Francesca Martini, Zurab Ninish, Kelley S. Yan, Kazuhiko Yamada, Munemasa Mori
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Mesothelial cells, in the outermost layer of internal organs, are essential for both organ development and homeostasis. Although the parietal mesothelial cell is the primary origin of mesothelioma that may highjack developmental signaling, the signal
Externí odkaz:
https://doaj.org/article/ba0a2b8b8e9045a7b7568d286481c4b9
Publikováno v:
Journal of Integrative Agriculture, Vol 23, Iss 5, Pp 1644-1657 (2024)
Bone morphogenetic protein 4 (BMP4) can induce the formation of chicken primordial germ cells (PGCs) in vitro; however, its regulatory mechanism in poultry remains unknown. This study aimed to use RNA-seq to analyze PGCs in chicken embryos and iPGCs
Externí odkaz:
https://doaj.org/article/c7213b315a6c4e5f8701362529f23632
Autor:
Lap Hing Chi, Andrew D. Redfern, Suraya Roslan, Ian P. Street, Allan D. Burrows, Robin L. Anderson
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Bone morphogenetic protein 4 (BMP4) is a potent inhibitor of breast cancer metastasis. However, a tumor-promoting effect of BMP4 is reported in other tumor types, especially when SMAD4 is inactive. Methods To assess the requiremen
Externí odkaz:
https://doaj.org/article/e48a0f7128ba4bec9bb1b96bd010468f
Autor:
Santosh Kumar, Zobia Umair, Vijay Kumar, Ravi Shankar Goutam, Soochul Park, Unjoo Lee, Jaebong Kim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The Bmp/Smad1 pathway plays a crucial role in developmental processes and tissue homeostasis. Mitogen-activated protein kinase (Mapk)/Erk mediated phosphorylation of Smad1 in the linker region leads to Smad1 degradation, cytoplasmic retentio
Externí odkaz:
https://doaj.org/article/a772200bad67419496b8b1a95d12e036
Akademický článek
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Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Introduction: Nail stem cell (NSC) differentiation plays a vital role in maintaining nail homeostasis and facilitating digit regeneration. Recently, onychofibroblasts (OFs), specialized mesenchymal cells beneath the nail matrix, have emerged as poten
Externí odkaz:
https://doaj.org/article/661734d5160a4698b4bb2fd6737c2893
Autor:
Sutong Xu, Xi Zhang, Zhuoqun Li, Chenming Liu, Qiulu Liu, Huazhen Chai, Hongkai Yao, Yuping Luo, Siguang Li, Chun Li
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Bone morphogenetic protein-4 (BMP4) is involved in regulation of neural stem cells (NSCs) proliferation, differentiation, migration and survival. It was previously thought that the treatment of NSCs with BMP4 alone induces astrocytes, whereas the tre
Externí odkaz:
https://doaj.org/article/5a8f20e6c19a42668bfb4f95b973be26
Autor:
Xiaojie Liu, Xi Jiang, Jing Hu, Mingxing Ding, Sang Ki Lee, Mallikarjuna Korivi, Yongdong Qian, Ting Li, Lifeng Wang, Wei Li
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundPerivascular adipose tissue (PVAT) dysfunction impairs vascular homeostasis. Impaired inflammation and bone morphogenetic protein-4 (BMP4) signaling are involved in thoracic PVAT dysfunction by regulating adipokine secretion and adipocyte p
Externí odkaz:
https://doaj.org/article/26bc25955db04dd2aca035113df5bdc9
Autor:
Gaoda Ju, Tao Xing, Miaomiao Xu, Xin Zhang, Yuqing Sun, Zhuanzhuan Mu, Di Sun, Sen Miao, Li Li, Jun Liang, Yansong Lin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 49, Iss , Pp 100972- (2024)
Papillary thyroid cancer (PTC) is the most prevalent endocrine cancer worldwide. Approximately 30 % of PTC patients will progress into the advanced or metastatic stage and have a relatively poor prognosis. It is well known that epithelial-mesenchymal
Externí odkaz:
https://doaj.org/article/48064c8304a14f85badb3264bf1a3f1c