Zobrazeno 1 - 10
of 2 443
pro vyhledávání: '"BMI1"'
Publikováno v:
Journal of Orthopaedic Translation, Vol 46, Iss , Pp 129-142 (2024)
Background: Age-related mandibular osteoporosis frequently causes loose teeth, difficulty eating, and disfiguration in elders. Bmi1−/− mice displaying accelerated skeletal aging represent a useful model for testing interventions against premature
Externí odkaz:
https://doaj.org/article/9884dc32d41f4ff8bd257cf7a23aa4bc
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Multiple studies have shown knockdown of chromobox 7 (CBX7) promotes the regenerative capacity of various cells or tissues. We examined the effect of CBX7 on hepatocyte proliferation and liver regeneration after 2/3 hepatectomy in a mouse mo
Externí odkaz:
https://doaj.org/article/337c5c5294c94e06a5345d912c13654e
Autor:
Shantanu Gupta, Daner A. Silveira, Gabriel P.S. Piedade, Miguel P. Ostrowski, José Carlos M. Mombach, Ronaldo F. Hashimoto
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 1, Pp 185-193 (2024)
Patients with non-small cell lung cancer (NSCLC) are often treated with chemotherapy. Poor clinical response and the onset of chemoresistance limit the anti-tumor benefits of drugs such as cisplatin. According to recent research, metastasis-associate
Externí odkaz:
https://doaj.org/article/24586555d16442aa80f64832dd5278eb
Autor:
Tianzhu Lv, Hongjing Liu, Ling Mao, Yanrong Song, Lili Liao, Kun Zhong, Binbin Shuai, Yingkun Luo, Tingting Guo, Wentao Huang, Shenyingjie Zhang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Extracellular vesicles (EVs) have been revealed to facilitate the development of oral squamous cavity cell carcinoma (OCSCC), while its supporting role in lymph node metastases is under continuous investigation. This study aimed t
Externí odkaz:
https://doaj.org/article/5d9682fcda794107a386a707e825df51
Publikováno v:
Non-coding RNA Research, Vol 8, Iss 4, Pp 605-614 (2023)
Long non-coding RNA (lncRNA) distal-less homeobox 6 antisense RNA 1 (DLX6-AS1) is elevated in a variety of cancers, including non-small cell lung cancer (NSCLC) and cervical cancer. Although it was found that the microRNA-16-5p (miR-16), which is kno
Externí odkaz:
https://doaj.org/article/699461c02e434c4480b5fcbd518adb39
Publikováno v:
Cells, Vol 13, Iss 19, p 1672 (2024)
BMI1, also known as B lymphoma Mo-MLV insertion region 1, is a protein in the Polycomb group that is implicated in various cellular processes, including stem cell self-renewal and the regulation of cellular senescence. BMI1 plays a role in the regula
Externí odkaz:
https://doaj.org/article/abbe8c279c154b2e842197ad8c9b3046
Akademický článek
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Autor:
Guillermo Albericio, Marina Higuera, Paula Araque, Cristina Sánchez, Diego Herrero, Miguel A. García-Brenes, Laura Formentini, José Luis Torán, Carmen Mora, Antonio Bernad
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8815 (2024)
The adult mammalian heart has been demonstrated to be endowed with low but real turnover capacity, especially for cardiomyocytes, the key functional cell type. The source, however, of that turnover capacity remains controversial. In this regard, we h
Externí odkaz:
https://doaj.org/article/6acba955abce41f0bda7982a8cf57e8b
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 5718-5735 (2023)
Abstract The transformation of nonmuscle‐invasive bladder cancer (BLCa) to muscle‐invasive type and distant metastasis are the two major threats to patients after surgery. Thus, it is important to identify the key genes of BLCa cell invasion and
Externí odkaz:
https://doaj.org/article/ed92e4bd32fd4dc6a917b73ecae8fe12
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 38, Iss 12, Pp 1190-1202 (2022)
Abstract The Nod‐like receptor (NLR) family CARD domain containing 5 (NLRC5) has been reported as an activator of human leukocyte antigen (HLA) class I that is responsible for immune activity in cancer treatment. This work focuses on the role of BM
Externí odkaz:
https://doaj.org/article/7241fb377bcb4b36b4ddefe813f27a34