Zobrazeno 1 - 10 of 57 pro vyhledávání: '"BLOM, NR"'
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Mitochondrial disruption and limited apoptosis of erythroblasts are associated with high risk myelodysplasia. An ultrastructural analysis
Autor: van de Loosdrecht, AA, Brada, SJL, Blom, NR, Smit, JW, van den Berg, E, de Wolf, JTM, Vellenga, E
Publikováno v: Leukemia Research, 25(5), 385-393. PERGAMON-ELSEVIER SCIENCE LTD
Aims: To investigate the ultrastructural characteristics of erythroblasts in myelodysplasia (MDS) which might be of additional importance in understanding its pathogenesis. Methods and results: 22 patients were classified according to FAB (French-Ame
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::efeca04c4648860d96579c65352baef7
https://research.rug.nl/en/publications/ebd11335-b048-4925-9a83-8c97bb7d28ad
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2
The in vitro effects of cytokines on expansion and migration of megakaryocyte progenitors
Autor: Drayer, AL, Sibinga, CTS, Blom, NR, de Wolf, JTM, Vellenga, E
Publikováno v: British Journal of Haematology, 109(4), 776-784. Wiley
Increasing the number of megakaryocyte progenitors in stem cell transplants by ex vivo expansion culture may be an approach to accelerate platelet recovery in patients undergoing high-dose chemotherapy. We evaluated the effect of three different cyto
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::6f4f1d2c0a411c2e136016583ef8a492
https://research.rug.nl/en/publications/b95f4824-bf46-433c-9b63-04085072f21c
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3
Excessive apoptosis of bone marrow erythroblasts in a patient with autoimmune haemolytic anaemia with reticulocytopenia
Autor: Van de Loosdrecht, AA, Blom, NR, Smit, JW, De Wolf, JTM, Vellenga, E
Publikováno v: British Journal of Haematology, 108(2), 313-315. Wiley
We report a patient with autoimmune haemolytic anaemia (AIHA) with reticulocytopenia, who showed excessive apoptosis of erythroblasts. Ultrastructural analysis of bone marrow cells showed that 50% of erythroblasts had characteristic features of apopt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::1dca7e0b05bb6b8703d16acd76e540d1
https://research.rug.nl/en/publications/6ac61023-85b3-4bb7-a342-7768fd3059b8
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4
A simple procedure for in situ immunolabeling, embedding and sectioning of layers of cultured endothelial and smooth muscle cells for both light and electron microscopy
Autor: Mulder, AB, Blom, NR, vanderMeer, J, Halie, MR, Smit, JW
Publikováno v: Biotechnic & histochemistry, 72(1), 45-48. Taylor & Francis Group
We present a simple procedure for in situ immunolabeling, embedding and sectioning of layers of cultured endothelial and smooth muscle cells for both light and electron microscopy. Endothelial and smooth muscle cells were seeded in tissue culture cha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::a2fd45de614c607db6ad0a4e69d340c7
https://research.rug.nl/en/publications/9054f1a1-5e6d-4536-abb9-e946edf096c6
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6
Association of smooth muscle cell tissue factor with caveolae
Autor: Mulder, AB, Smit, JW, Bom, VJJ, Blom, NR, Ruiters, MHJ, Halie, MR, vanderMeer, J
Publikováno v: Blood, 88(4), 1306-1313. AMER SOC HEMATOLOGY
There is still no satisfactory explanation for the low catalytic activity of tissue factor (TF)/factor VII(a) complexes towards coagulation factor X, as found on the apical surface side of cell layers. It has been hypothesized that TF exists in a lat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::0a2819dde9b05f8c6e8d1209da9fee11
https://research.rug.nl/en/publications/c9ee85e0-8dc8-4ced-865f-93e513befbf1
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7
BASAL TISSUE FACTOR EXPRESSION IN ENDOTHELIAL-CELL CULTURES IS CAUSED BY CONTAMINATING SMOOTH-MUSCLE CELLS - REDUCTION BY USING CHYMOTRYPSIN INSTEAD OF COLLAGENASE
Autor: MULDER, AB, BLOM, NR, SMIT, JW, RUITERS, MHJ, VANDERMEER, J, HALIE, MR, BOM, VJJ
Publikováno v: Thrombosis Research, 80(5), 399-411. PERGAMON-ELSEVIER SCIENCE LTD
A discrepancy exists between basal tissue factor (TF) expression found in endothelial cell cultures and the failure to detect TF in unpertubated endothelial cells in vivo. We demonstrated that basal TF expression in endothelial cell cultures originat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::d208e594f63c2bd3c3a2923ce6920ca9
https://research.rug.nl/en/publications/9b2fd7a6-741b-4014-86e1-23ab04fd7c89
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9
NATURAL-KILLER-CELL SURFACE-MARKERS ON CELLS CONTAINING PARALLEL TUBULAR STRUCTURES
Autor: HOOGEVEEN, YL, BLOM, NR, HALIE, MR, SMIT, JW
Publikováno v: Natural immunity, 11(2), 69-77
Parallel tubular structures (PTS) and/or the associated electron-dense granules, thought to contain molecules responsible for target cell lysis, can be detected in the cytoplasm of lymphocytes with large granular lymphocyte (LGL) morphology. In the p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::712aaf772874dc709340f62506bf3e8b
https://research.rug.nl/en/publications/85e0912a-147a-4711-a589-2de2968a7ab2
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10
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