Výsledky vyhledávání - "BLI, bioluminescence imaging"

Hypoxia Patterns in Primary and Metastatic Prostate Cancer Environments1

Autor: Bharti, Santosh Kumar, Kakkad, Samata, Danhier, Pierre, Wildes, Flonne, Penet, Marie-France, Krishnamachary, Balaji, Bhujwalla, Zaver M.

Publikováno v: Neoplasia (New York, N.Y.)

Metastatic dissemination continues to be a major cause of prostate cancer (PCa) mortality, creating a compelling need to understand factors that play a role in the metastatic cascade. Since hypoxia plays an important role in PCa aggressiveness, we ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c6f38356a6e9ab880a6ca22b1093aec1
http://europepmc.org/articles/PMC6327878

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Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy

Publikováno v: EBioMedicine
EBioMedicine, Vol 19, Iss C, Pp 49-59 (2017)

Bone is one of the most preferred sites of metastasis in lung cancer. Currently, bisphosphonates and denosumab are major agents for controlling tumor-associated skeletal-related events (SREs). However, both bisphosphonates and denosumab significantly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df0874d7a8112b71eab7fbb3fa59c38
http://europepmc.org/articles/PMC5440603

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Exploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathway

Autor: Hans J. Baelde, Yvonne de Jong, Alwine B. Kruisselbrink, Judith V.M.G. Bovée, Gaia Alberti, Ruben D. Addie, Ivo Que

Publikováno v: Journal of Bone Oncology
Journal of Bone Oncology, Vol 15, Iss, Pp-(2019)
Journal of Bone Oncology, 15

Background: Chondrosarcomas are malignant cartilage-producing tumors showing mutations and changes in gene expression in metabolism related genes. In this study, we aimed to explore the metabolome and identify targetable metabolic vulnerabilities in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7d79808d86885bfd99a241e896ee8f
https://pubmed.ncbi.nlm.nih.gov/30766792

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Cousins at work: How combining medical with optical imaging enhances in vivo cell tracking

Autor: Alessia, Volpe, Ewelina, Kurtys, Gilbert O, Fruhwirth

Publikováno v: The International Journal of Biochemistry & Cell Biology

Microscopy and medical imaging are related in their exploitation of electromagnetic waves, but were developed to satisfy differing needs, namely to observe small objects or to look inside subjects/objects, respectively. Together, these techniques can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ea6734ea0c6764c5aa7c2adf4e2bd4f0
https://pubmed.ncbi.nlm.nih.gov/29960079

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Combining Optical Reporter Proteins with Different Half-lives to Detect Temporal Evolution of Hypoxia and Reoxygenation in Tumors

Autor: Yelena Mironchik, Balaji Krishnamachary, Santosh Kumar Bharti, Zaver M. Bhujwalla, Samata Kakkad, Pierre Danhier

Publikováno v: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 12, Pp 871-881 (2015)

Here we have developed a hypoxia response element driven imaging strategy that combined the hypoxia-driven expression of two optical reporters with different half-lives to detect temporal changes in hypoxia and hypoxia inducible factor (HIF) activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ad3f708ca051464c405ab306bb45b5

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ヒトガタシキュウナイマクショウモデルマウスノサクセイトソノヒシンシュウテキリアルタイムカイセキシステムノカイハツ

Publikováno v: 科学研究費補助金研究成果報告書.

我々は、少量の子宮内膜細胞を重度免疫不全マウスの腎被膜下へ移植することで均一の異所性内膜様組織を持つモデルを作成し、その内膜様組織の非侵襲的かつリアルタイムな定量化が�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::b4525bc9ff14cac725d8d567f7335d55
https://koara.lib.keio.ac.jp/xoonips/modules/xoonips/detail.php?koara_id=KAKEN_19791162seika

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Evaluating infusate parameters for direct drug delivery to the brainstem: a comparative study of convection-enhanced delivery versus osmotic pump delivery.

Autor: Rechberger JS; 1Department of Neurologic Surgery, Mayo Clinic., Power EA; 1Department of Neurologic Surgery, Mayo Clinic.; 2Mayo Clinic Graduate School of Biomedical Sciences., Lu VM; 1Department of Neurologic Surgery, Mayo Clinic., Zhang L; 1Department of Neurologic Surgery, Mayo Clinic., Sarkaria JN; 3Department of Radiation Oncology; and., Daniels DJ; 1Department of Neurologic Surgery, Mayo Clinic.; 4Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota.

Publikováno v: Neurosurgical focus [Neurosurg Focus] 2020 Jan 01; Vol. 48 (1), pp. E2.

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Akademický článek

Exploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathway.

Autor: Addie RD; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., de Jong Y; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., Alberti G; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., Kruisselbrink AB; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., Que I; Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands., Baelde H; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., Bovée JVMG; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands.

Publikováno v: Journal of bone oncology [J Bone Oncol] 2019 Jan 29; Vol. 15, pp. 100222. Date of Electronic Publication: 2019 Jan 29 (Print Publication: 2019).

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