Zobrazeno 1 - 10 of 233 pro vyhledávání: '"BL Gallie"'
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Akademický článek
DNA hypermethylation/boundary control loss identified in retinoblastomas associated with genetic and epigenetic inactivation of the RB1 gene promoter
Autor: AM Raizis, HM Racher, A Foucal, H Dimaras, BL Gallie, PM George
Publikováno v: Epigenetics, Vol 16, Iss 9, Pp 940-954 (2021)
DNA hypermethylation events occur frequently in human cancers, but less is known of the mechanisms leading to their initiation. Retinoblastoma, an intraocular cancer affecting young children, involves bi-allelic inactivation of the RB1 gene (RB−/-)
Externí odkaz: https://doaj.org/article/a1205ff93b954287bcba2de56d34fcec
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5
Loss of Rb and Myc activation co-operate to suppress cyclin D1 and contribute to transformation
Autor: Ww, Marhin, Yj, Hei, Chen S, Jiang Z, Bl, Gallie, Ra, Phillips, Linda Penn
Publikováno v: Europe PubMed Central
Cyclin D1 can bind and phosphorylate the product (pRb) of the retinoblastoma gene (RB-1) and recent evidence suggests pRb, in turn, may regulate cyclin D1 protein expression. In transformed cell lines, loss of pRb activity strongly correlates with a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e022b9435684a43cdd5b2d34cfa268ba
http://europepmc.org/abstract/med/8552398
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6
Expression patterns of the E2F family of transcription factors during murine epithelial development
Autor: Dagnino L, Cj, Fry, Sm, Bartley, Peggy Farnham, Bl, Gallie, Ra, Phillips
Publikováno v: Europe PubMed Central
The E2F family of transcription factors includes five E2F and three DP forms. E2F is involved in the regulation of cell proliferation, but little is known about E2F function during vertebrate development. We have explored the regulation of E2F expres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f0b67a7ab0bc88d58d9a15e0a045e1fb
http://europepmc.org/abstract/med/9149906
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7
Akademický článek
Single- Versus Triple-Agent Intra-Arterial Chemotherapy for Retinoblastoma.
Autor: Alshahrani NO; From the Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children (N.O.A., K.C., A.M., B.L.G., S.N.K.), Toronto, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto (N.O.A., A.M., B.L.G., S.N.K.), Toronto, Canada; Department of Ophthalmology, Prince Sultan Military Medical City (N.O.A.), Riyadh, Saudi Arabia., Aldhawi A; Diagnostic Imaging, Hospital for Sick Children, University of Toronto (A.A., P.M., C.P.-F.), Toronto, Canada., Feng ZX; Department of Ophthalmology, University of Ottawa (Z.X.F.), Ottawa, Canada., Chau K; From the Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children (N.O.A., K.C., A.M., B.L.G., S.N.K.), Toronto, Canada., Mallipatna A; From the Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children (N.O.A., K.C., A.M., B.L.G., S.N.K.), Toronto, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto (N.O.A., A.M., B.L.G., S.N.K.), Toronto, Canada., Muthusami P; Diagnostic Imaging, Hospital for Sick Children, University of Toronto (A.A., P.M., C.P.-F.), Toronto, Canada., Parra-Farinas C; Diagnostic Imaging, Hospital for Sick Children, University of Toronto (A.A., P.M., C.P.-F.), Toronto, Canada., Zaarour C; Department of Anesthesiology and Pain Medicine, The Hospital for Sick Children (C.Z.), Toronto, Canada., Shaikh F; Department of Haematology/Oncology, The Hospital for Sick Children (F.S.), Toronto, Canada., Gallie BL; From the Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children (N.O.A., K.C., A.M., B.L.G., S.N.K.), Toronto, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto (N.O.A., A.M., B.L.G., S.N.K.), Toronto, Canada., Kletke SN; From the Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children (N.O.A., K.C., A.M., B.L.G., S.N.K.), Toronto, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto (N.O.A., A.M., B.L.G., S.N.K.), Toronto, Canada. Electronic address: stephanie.kletke@sickkids.ca.
Publikováno v: American journal of ophthalmology [Am J Ophthalmol] 2024 Oct 10; Vol. 269, pp. 488-496. Date of Electronic Publication: 2024 Oct 10.
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8
Akademický článek
Digital retinoblastoma documentation supports care and research.
Autor: Gallie BL; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON; International Retinoblastoma Consortium; Princess Margaret Cancer Center/University Health Network, Toronto, ON; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON; Temerty Faculty of Medicine, University of Toronto, Toronto, ON.. Electronic address: brenda.gallie@sickkids.ca., Flegg K; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON; International Retinoblastoma Consortium., Truong T; Princess Margaret Cancer Center/University Health Network, Toronto, ON., Liu J; Princess Margaret Cancer Center/University Health Network, Toronto, ON., Gavrylyuk Y; Princess Margaret Cancer Center/University Health Network, Toronto, ON., Chau K; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON., Kletke S; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON; Temerty Faculty of Medicine, University of Toronto, Toronto, ON., Malliipatna A; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON; Temerty Faculty of Medicine, University of Toronto, Toronto, ON., Sheikh F; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON; Temerty Faculty of Medicine, University of Toronto, Toronto, ON., Soroka S; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON; International Retinoblastoma Consortium., Ozkurt ZG; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON; Department of Ophthalmology, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH., Alshahran N; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON; Ophthalmology Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia., Jong A; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON; McMaster University, Hamilton, ON., Janusonis I; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON; Temerty Faculty of Medicine, University of Toronto, Toronto, ON.
Publikováno v: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie [Can J Ophthalmol] 2024 Jul 31. Date of Electronic Publication: 2024 Jul 31.
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9
Editorial & Opinion
Let's achieve a fair world for all children affected by retinoblastoma.
Autor: Gallie BL; Hospital for Sick Children, Alberta Children's Hospital, Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada.; TECHNA and Krembil Research Institutes, UHN, University of Toronto, Toronto, Canada.; Ophthalmology, Medical Biophysics, Molecular Genetics, University of Toronto, Toronto, Canada.
Publikováno v: Clinical & experimental ophthalmology [Clin Exp Ophthalmol] 2024 Apr; Vol. 52 (3), pp. 256-257.
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10
Akademický článek
A typical anterior retinoblastoma: diagnosis by aqueous humor cell-free DNA analysis.
Autor: Kletke SN; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, Canada.; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada., Soliman S; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, Canada.; Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt., Racher H; Scientific and Laboratory Operations, Dynacare/Impact Genetics, Brampton, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada., Mallipatna A; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, Canada.; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada., Shaikh F; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada.; Department of Paediatrics, University of Toronto, Toronto, Canada., Mireskandari K; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, Canada.; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada., Gallie BL; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, Canada.; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.
Publikováno v: Ophthalmic genetics [Ophthalmic Genet] 2022 Dec; Vol. 43 (6), pp. 862-865. Date of Electronic Publication: 2022 Nov 03.
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