L-selectin expression defines a subpopulation of In vitro generated AML-reactive T-cells with superior anti-leukemic efficacy for adoptive immunotherapy

Autor: BJ Weigel, ME Ericson, BL Levine, CH June, Martin Sauer, Karl Welte, BR Blazar

Publikováno v: Klinische Pädiatrie. 216

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fc7c045d0c0bfb381f0b2db85064212
https://doi.org/10.1055/s-2004-828590

A Phase 1 Study of ABI-009 (Nab-sirolimus) in Combination With Temozolomide and Irinotecan in Pediatric Patients With Recurrent or Refractory Solid Tumors, Including CNS Tumors-A Children's Oncology Group Pediatric Early Phase Clinical Trial Network Study ADVL1514.

Autor: Cramer SL; Prisma Health-Midlands Children's Center for Cancer and Blood Disorders, Columbia, South Carolina, USA., Reddy AT; Neurology/Child Neurology, UCSF Medical Center-Mission Bay, San Francisco, California, USA., Minard CG; Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Dan L. Duncan Institute, Houston, Texas, USA., Voss S; Dana Farber Cancer Institute, Children's Hospital of Boston, Boston, Massachusetts, USA., Fox E; Cancer Center, Clinical Trials Administration, Saint Jude Children's Research Hospital, Memphis, Tennessee, USA., Liu X; Children's Oncology Group, Monrovia, California, USA., Denic K; Mayo Clinic, Rochester, Minnesota, USA., Reid JM; Mayo Clinic, Rochester, Minnesota, USA., Weigel BJ; Department of Pediatrics, Hem/Onc/BMT, University of Minnesota Medical Center-Fairview, Minneapolis, Minnesota, USA.

Publikováno v: Cancer medicine [Cancer Med] 2024 Nov; Vol. 13 (21), pp. e70376.

Efficacy of the Allosteric MEK Inhibitor Trametinib in Relapsed and Refractory Juvenile Myelomonocytic Leukemia: a Report from the Children's Oncology Group.

Autor: Stieglitz E; Department of Pediatrics, Benioff Children's Hospitals, University of California San Francisco, San Francisco, California., Lee AG; Department of Pediatrics, Benioff Children's Hospitals, University of California San Francisco, San Francisco, California., Angus SP; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana., Davis C; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana., Barkauskas DA; Children Oncology Group Operations and Data Center, Monrovia, California., Hall D; Children Oncology Group Operations and Data Center, Monrovia, California., Kogan SC; Department of Laboratory Medicine, University of California San Francisco, San Francisco, California., Meyer J; Department of Pediatrics, Benioff Children's Hospitals, University of California San Francisco, San Francisco, California., Rhodes SD; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.; Division of Pediatric Hematology-Oncology, Indiana University School of Medicine, Indianapolis, Indiana., Tasian SK; Children's Hospital of Philadelphia, Division of Oncology and Center for Childhood Cancer Research and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania., Xuei X; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana., Shannon K; Department of Pediatrics, Benioff Children's Hospitals, University of California San Francisco, San Francisco, California., Loh ML; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute and Department Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, Washington., Fox E; St. Jude Children's Research Hospital, Memphis, Tennessee., Weigel BJ; University of Minnesota, Minneapolis, Minnesota.

Publikováno v: Cancer discovery [Cancer Discov] 2024 Sep 04; Vol. 14 (9), pp. 1590-1598.

Phase II Study of Samotolisib in Children and Young Adults With Tumors Harboring Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Pathway Alterations: Pediatric MATCH APEC1621D.

Autor: Laetsch TW; Children's Hospital of Philadelphia/University of Pennsylvania, Philadelphia, PA., Ludwig K; University of Texas Southwestern, Dallas, TX., Williams PM; Frederick National Laboratory for Cancer Research, Frederick, MD., Roy-Chowdhuri S; University of Texas MD Anderson Cancer Center, Houston, TX., Patton DR; Center for Biomedical Informatics and Information Technology, NCI, NIH, Bethesda, MD., Coffey B; Center for Biomedical Informatics and Information Technology, NCI, NIH, Bethesda, MD., Reid JM; Mayo Clinic Comprehensive Cancer Center, Rochester, MN., Piao J; Keck School of Medicine, University of Southern California, Los Angeles, CA., Saguilig L; Children's Oncology Group Statistical Center, Monrovia, CA., Alonzo TA; Keck School of Medicine, University of Southern California, Los Angeles, CA., Berg SL; Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX., Mhlanga J; Washington University School of Medicine, St Louis, MO., Fox E; St Jude Children's Research Hospital, Memphis, TN., Weigel BJ; University of Minnesota, Minneapolis, MN., Hawkins DS; Seattle Children's Hospital and University of Washington, Seattle, WA., Mooney MM; Division of Cancer Treatment and Diagnosis, Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD., Takebe N; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD., Tricoli JV; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD., Janeway KA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA., Seibel NL; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD., Parsons DW; Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX.

Publikováno v: JCO precision oncology [JCO Precis Oncol] 2024 Sep; Vol. 8, pp. e2400258.

Toxicity Profile of eBAT, a Bispecific Ligand-Targeted Toxin Directed to EGFR and uPAR, in Mice and a Clinical Dog Model.

Autor: Dicovitsky RH; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Schappa JT; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Experimental Surgical Services, Department of Surgery, Medical School, University of Minnesota, Minneapolis, MN 55455, USA., Schulte AJ; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Lang HP; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Comparative Molecular Biosciences Graduate Program and DVM-PhD Dual Degree Program, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Kuerbitz E; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Roberts S; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., DePauw TA; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Microbiology, Immunology, and Cancer Biology Graduate Program, Medical School, University of Minnesota, Minneapolis, MN 55455, USA., Lewellen M; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Winter AL; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Stuebner K; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Buettner M; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Reid K; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Bergsrud K; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Pracht S; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Chehadeh A; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Feiock C; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., O'Sullivan MG; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Carlson T; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Armstrong AR; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA., Meritet D; Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA., Henson MS; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Weigel BJ; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, MN 55455, USA., Modiano JF; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Laboratory Medicine and Pathology, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.; Stem Cell Institute, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Engineering in Medicine, University of Minnesota, Minneapolis, MN 55455, USA., Borgatti A; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Clinical Investigation Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA., Vallera DA; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Radiation Oncology, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.

Publikováno v: Toxins [Toxins (Basel)] 2024 Aug 26; Vol. 16 (9). Date of Electronic Publication: 2024 Aug 26.