Zobrazeno 1 - 10
of 703
pro vyhledávání: '"BIRC5"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Objective Accumulating studies reported the crucial roles of tRFs in tumorigenesis. However, their further mechanisms and clinical values remains unclear. This study aimed at the further investigation of tRF-Leu in breast cancer chemotherapy
Externí odkaz:
https://doaj.org/article/dbc682b4d75b438a856d553e9cde5cea
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Receptor-type tyrosine-protein phosphatase T (PTPRT) is a transmembrane protein that is involved in cell adhesion. We previously found that PTPRT was downregulated in multiple cancer types and the mutation of PTPRT was associated
Externí odkaz:
https://doaj.org/article/d348f3605cdd430db19da6f81972b79e
Autor:
Qing Li, Haiyan Liu, Han Wang, Wenzhuo Xiong, Liping Dai, Xiuzhi Zhang, Peng Wang, Hua Ye, Jianxiang Shi, Zhihao Fang, Keyan Wang
Publikováno v:
PeerJ, Vol 12, p e17494 (2024)
Background Autoantibodies targeting tumor-associated antigens (TAAbs) have emerged as promising biomarkers for early cancer detection. This research aimed to assess the diagnostic capacity of anti-BIRC5 autoantibody in detecting AFP-negative hepatoce
Externí odkaz:
https://doaj.org/article/dea0399bf2b6461199b6f87d5e63beda
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 16370-16385 (2023)
Abstract Background Preclinical studies and clinical trials have demonstrated that tumor‐intrinsic activation of the cell cycle program impedes anticancer immunotherapy. Identification of cell cycle‐related biomarkers may provide novel therapeuti
Externí odkaz:
https://doaj.org/article/1a8ba3f6252848bdb256d737c0dddcc0
Autor:
Yadan Fan, Yinglian Pan, Liping Jia, Shuzhen Gu, Binxin Liu, Ziman Mei, Chunyan Lv, Haohao Huang, Genhai Zhu, Qingchun Deng
Publikováno v:
Cancer Medicine, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Cisplatin‐based chemotherapy is the standard treatment for metastatic ovarian cancer (OC). However, chemoresistance continues to pose significant clinical challenges. Recent research has highlighted the baculoviral inhibitor of the apoptos
Externí odkaz:
https://doaj.org/article/dbf3123251444d0689da106eab0a461f
Autor:
Sven Hagemann, Danny Misiak, Jessica L. Bell, Tommy Fuchs, Marcell I. Lederer, Nadine Bley, Monika Hämmerle, Ehab Ghazy, Wolfgang Sippl, Johannes H. Schulte, Stefan Hüttelmaier
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-23 (2023)
Abstract Background Neuroblastoma is the most common solid tumor in infants accounting for approximately 15% of all cancer-related deaths. Over 50% of high-risk neuroblastoma relapse, emphasizing the need of novel drug targets and therapeutic strateg
Externí odkaz:
https://doaj.org/article/ca683df65b6941eab6938839b5d6ab26
Autor:
Mengqiu Wu, Qianqian Jin, Xinyue Xu, Jiaojiao Fan, Weiyi Chen, Mengqiu Miao, Ran Gu, Shengnan Zhang, Yan Guo, Songming Huang, Yue Zhang, Aihua Zhang, Zhanjun Jia
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Renal fibrosis is a common characteristic of various chronic kidney diseases (CKDs) driving the loss of renal function. During this pathological process, persistent injury to renal tubular epithelial cells and activation of fibroblasts chief
Externí odkaz:
https://doaj.org/article/6060646513964417864527760b606ba0
Autor:
Zihao He, Kai Gao, Lei Dong, Liu Liu, Xinchi Qu, Zhengkai Zou, Yang Wu, Dechao Bu, Jin-Cheng Guo, Yi Zhao
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1557-1572 (2023)
A complex and vast biological network regulates all biological functions in the human body in a sophisticated manner, and abnormalities in this network can lead to disease and even cancer. The construction of a high-quality human molecular interactio
Externí odkaz:
https://doaj.org/article/6d0cda60712146cda04a784d356c97c0
Autor:
Zhi‐Hao Yu, Zhao‐Hui Chen, Guang‐Lei Zhou, Xue‐Jie Zhou, Hai‐Yan Ma, Yue Yu, Xin Wang, Xu‐Chen Cao
Publikováno v:
Thoracic Cancer, Vol 13, Iss 21, Pp 2992-3000 (2022)
Abstract Background Breast cancer remains the most common malignancy in females around the world. Recently, a growing number of studies have focused on gene dysregulation. In our previous study, Krüppel‐like factors (KLFs) were found to play essen
Externí odkaz:
https://doaj.org/article/6553544d215a4607aeed2fb89fdff0a4
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17101- (2023)
Colorectal cancer (CRC) is the third most diagnosed malignancy and the second leading cause of cancer death. The objective was to identify novel hub genes that were helpful for prognosis and targeted therapy in CRC. GSE23878, GSE24514, GSE41657, GSE8
Externí odkaz:
https://doaj.org/article/fe0fecf9079d4ba2ad54fce5b2200698