Zobrazeno 1 - 10
of 8 987
pro vyhledávání: '"BIOCONJUGATION"'
Autor:
Shinichi Sato, Shogo Miyano, Keita Nakane, Zhengyi Liu, Munehiro Kumashiro, Tomohide Saio, Yuya Tanaka, Akira Shigenaga, Chizu Fujimura, Eri Koyanagi, Hafumi Nishi, Shusuke Tomoshige, Minoru Ishikawa
Publikováno v:
Tetrahedron Chem, Vol 12, Iss , Pp 100111- (2024)
Our ex situ tyrosine bioconjugation method utilizes the oxidation of N-methylurazole by Bobbitt's salt or electrochemical activation to generate stable radicals for selective tyrosine labeling, thereby addressing the longstanding challenges in protei
Externí odkaz:
https://doaj.org/article/a0400cbecd224dc386991e75fa935f8a
Autor:
Jacquelyn Blake-Hedges, Dan Groff, Wilson Foo, Jeffrey Hanson, Elenor Castillo, Miao Wen, Diana Cheung, Mary Rose Masikat, Jian Lu, Young Park, Nina Abi Carlos, Hans Usman, Kevin Fong, Abigail Yu, Sihong Zhou, Joyce Kwong, Cuong Tran, Xiaofan Li, Dawei Yuan, Trevor Hallam, Gang Yin
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Therapeutic bioconjugates are emerging as an essential tool to combat human disease. Site-specific conjugation technologies are widely recognized as the optimal approach for producing homogeneous drug products. Non-natural amino acid (nnAA) incorpora
Externí odkaz:
https://doaj.org/article/1e674937a64d456a8d216791a8a935ac
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 767-776 (2024)
A carboranylporphyrin of A3B-type bearing a single pentafluorophenyl ring was prepared through the regioselective nucleophilic aromatic substitution reaction of the p-fluorine atoms in 5,10,15,20-tetrakis(pentafluorophenyl)porphyrin with 9-mercapto-m
Externí odkaz:
https://doaj.org/article/cb0f745a2a554eafa763f16ae9429298
Publikováno v:
Heliyon, Vol 11, Iss 1, Pp e40894- (2025)
HRP, or horseradish peroxidase, is a reporter enzyme with extensive use in biotechnological applications. We previously reported the purification and characterization of two anionic peroxidases from Raphanus sativus L. var niger (black radish) roots.
Externí odkaz:
https://doaj.org/article/a5ab6ae040fa41bfad867e4c7ce5bd02
Publikováno v:
Tetrahedron Chem, Vol 11, Iss , Pp 100088- (2024)
While their broad utility in various chemistry fields were well recognized for decades, fluoroalcohols have recently emerged as a unique solvent system for bioconjugation development. This review describes examples and roles of fluoroalcohols such as
Externí odkaz:
https://doaj.org/article/d69001241c9649cb84b0d0de4cc5cc89
Autor:
Asad Syed, Abu Baker, Mohamed Mohany, Abdallah M. Elgorban, Mohd Sajid Khan, Salim S. Al-Rejaie
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 51, Iss 1, Pp 384-396 (2023)
AbstractVincamine, a natural chemical, was used as a reducing agent in the synthesis of IgG antibodies mediated biogenic gold nanoparticles (IgGAuNPs). Eventually, the synthesised IgGAuNPs were bioconjugated with the chemotherapeutic drug methotrexat
Externí odkaz:
https://doaj.org/article/d0093eebc59847cb9e2eb8f4519e0b68
Akademický článek
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Autor:
Samantha Leier, Frank Wuest
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1270 (2024)
Background: The incorporation of radionuclides into peptides and larger biomolecules requires efficient and sometimes biorthogonal reaction conditions, to which click chemistry provides a convenient approach. Methods: Traditionally, click-based radio
Externí odkaz:
https://doaj.org/article/541ab2e439254ffcba35a49b6a5cb521
Autor:
Dóra Hegedűs, Nikoletta Szemerédi, Krisztina Petrinca, Róbert Berkecz, Gabriella Spengler, István Szatmári
Publikováno v:
Molecules, Vol 29, Iss 17, p 4176 (2024)
The reaction between glycine-type aminonaphthol derivatives substituted with 2- or 1-naphthol and indole or 7-azaindole has been tested. Starting from 2-naphthol as a precursor, the reaction led to the formation of ring-closed products, while in the
Externí odkaz:
https://doaj.org/article/479a55a4c868416d905ca785ad88cd33
Publikováno v:
Compounds, Vol 3, Iss 3, Pp 464-503 (2023)
Bioconjugation reactions are critical to the modification of peptides and proteins, permitting the introduction of biophysical probes onto proteins as well as drugs for use in antibody-targeted medicines. A diverse set of chemical reagents can be emp
Externí odkaz:
https://doaj.org/article/0fef385c0cb6444f84d2019023121149