Zobrazeno 1 - 10
of 60
pro vyhledávání: '"BHARATHI P SALIMATH"'
Autor:
Adel Zaid I. Mutahar, Manjunath Devaramani, Renu Dayal, Dinesh Kumar Saini, Paramahans V. Salimath, Bharathi P. Salimath
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Angiotensin-converting enzyme 2 (ACE2) and neuropilin 1, a vascular endothelial growth factor (VEGF) receptor, were identified to bind to the SARS-CoV-2 spike receptor-binding domain (spike RBD). In silico analysis based on 3D structure, multiple seq
Externí odkaz:
https://doaj.org/article/7c81365ea0c84a7b95e0f46d72ba2038
Autor:
Neelam Mishra, Kavita Rana, Siva Deepthi Seelam, Rakesh Kumar, Vijyendra Pandey, Bharathi P. Salimath, Dayanand Agsar
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
A biosurfactant producing bacterium was identified as Pseudomonas aeruginosa DNM50 based on molecular characterization (NCBI accession no. MK351591). Structural characterization using MALDI-TOF revealed the presence of 12 different congeners of rhamn
Externí odkaz:
https://doaj.org/article/c6f867e64c444ad699994ee646e3e8d5
Publikováno v:
Pharmaceutical Biology, Vol 55, Iss 1, Pp 1489-1499 (2017)
Context: Abnormal angiogenesis and evasion of apoptosis are hallmarks of cancer. Accordingly, anti-angiogenic and pro-apoptotic therapies are effective strategies for cancer treatment. Medicinal plants, namely, Eugenia jambolana Lam. (Myrtaceae), Mus
Externí odkaz:
https://doaj.org/article/feef0856521346b590d010c5901cb491
Introduction: 2-dimensional (2D) cell culture is commonly used for the evaluation of anticancer drugs, which is incapable of simulating the three dimensions (3D) microenvironment of the original tumors, therefore, a new pre-clinical platform for drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af7b2b53fe9eaffbc6eac324685a9cee
https://doi.org/10.21203/rs.3.rs-2019190/v1
https://doi.org/10.21203/rs.3.rs-2019190/v1
Publikováno v:
Chemico-Biological Interactions. 299:120-130
Approximately 15% of globally diagnosed breast cancers are designated as triple negative breast cancer (TNBC). In this study, we investigated the effect of the natural compound, Bis(2- ethyl hexyl) 1H-pyrrole-3,4-dicarboxylate (TCCP), purified from T
Autor:
B Yashaswini, Bharathi P. Salimath
Publikováno v:
IOSR Journal of Biotechnology and Biochemistry. :70-77
Tumor cells show differential sensitivity to cell death induced by TRAIL and also develop resistance to conventional radiation therapy along with several side effects being cytotoxic to normal cells. In this present study, we are focusing on tumor se
Publikováno v:
Pharmaceutical Biology, Vol 55, Iss 1, Pp 1489-1499 (2017)
Context: Abnormal angiogenesis and evasion of apoptosis are hallmarks of cancer. Accordingly, anti-angiogenic and pro-apoptotic therapies are effective strategies for cancer treatment. Medicinal plants, namely, Eugenia jambolana Lam. (Myrtaceae), Mus
Publikováno v:
Apoptosis. 21:578-593
TRAIL, an apoptosis inducing cytokine currently in phase II clinical trial, was investigated for its capability to induce apoptosis in six different human tumor cell lines out of which three cell lines showed resistance to TRAIL induced apoptosis. To
Autor:
Yashaswini Balaraju, Bharathi P. Salimath, Sumana Y. Kotian, Kavitha Rachaiah, Sathish Byrappa, K. M. L. Rai, Samudyata C. Prabhuswamimath
Publikováno v:
Anti-cancer agents in medicinal chemistry. 19(6)
Background:Triple Negative Breast Cancer (TNBC) tends to be more aggressive than other types of breast cancer. Resistance to chemotherapy is a major obstacle hence there is a significant need for new antineoplastic drugs with multi-target potency. Nu
Publikováno v:
Drug Discoveries & Therapeutics. 9:53-65
Anacardic acid is a major constituent of nutshell of cashew. In this study, we have isolated it from the leaves of Anacardium Occidentale L. using polarity-based fractionation and confirmed the structure using GC-MS, NMR and FT-IR. The main focus of