Zobrazeno 1 - 10
of 59
pro vyhledávání: '"BGT1"'
Autor:
Stefanie Kickinger, Maria E. K. Lie, Akihiro Suemasa, Anas Al-Khawaja, Koichi Fujiwara, Mizuki Watanabe, Kristine S. Wilhelmsen, Christina B. Falk-Petersen, Bente Frølund, Satoshi Shuto, Gerhard F. Ecker, Petrine Wellendorph
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The betaine/GABA transporter 1 (BGT1) is a member of the GABA transporter (GAT) family with still elusive function, largely due to a lack of potent and selective tool compounds. Based on modeling, we here present the design, synthesis and pharmacolog
Externí odkaz:
https://doaj.org/article/eb62ced04b7242589c80acca580e939a
Autor:
Pukale, Dipak Dadaso
Syringomyelia (SM) is a neurological disorder in which a fluid-filled cyst (syrinx) inside the spinal cord forms due to either congenital or acquired (spinal cord injury (SCI)) causes. SM is clinically treated only when it is required depending on th
Autor:
Kickinger, Stefanie, Lie, Maria E.K., Suemasa, Akihiro, Al-Khawaja, Anas, Fujiwara, Koichi, Watanabe, Mizuki, Wilhelmsen, Kristine S., Falk-Petersen, Christina B., Frølund, Bente, Shuto, Satoshi, Ecker, Gerhard F., Wellendorph, Petrine
Publikováno v:
Kickinger, S, Lie, M E K, Suemasa, A, Al-Khawaja, A, Fujiwara, K, Watanabe, M, Wilhelmsen, K S, Falk-Petersen, C B, Frølund, B, Shuto, S, Ecker, G F & Wellendorph, P 2021, ' Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1 ', Frontiers in Chemistry, vol. 9, 736457 . https://doi.org/10.3389/fchem.2021.736457
The betaine/GABA transporter 1 (BGT1) is a member of the GABA transporter (GAT) family with still elusive function, largely due to a lack of potent and selective tool compounds. Based on modeling, we here present the design, synthesis and pharmacolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::eaa602e13e572fd324f1e38aa70aa9d3
Autor:
Yun eZhou, Niels Christian Danbolt
Publikováno v:
Frontiers in Endocrinology, Vol 4 (2013)
The mammalian genome contains four genes encoding GABA transporters (GAT1, slc6a1; GAT2, slc6a13; GAT3, slc6a11; BGT1, slc6a12) and five glutamate transporter genes (EAAT1, slc1a3; EAAT2, slc1a2; EAAT3, slc1a1; EAAT4, slc1a6; EAAT5, slc1a7). These tr
Externí odkaz:
https://doaj.org/article/e55e3147237f4756ad1cfaaf7c780c7d
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Kidney International. 59:2182-2191
Hypertonic activation of the renal betaine/GABA transporter is microtubule dependent. Background Epithelial cells in the renal inner medulla accumulate osmolytes such as betaine to maintain normal cell volume during prolonged extracellular hypertonic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbb5460f9c8437deae6e4fd8446b643
https://doi.org/10.1046/j.1523-1755.2001.00733.x
https://doi.org/10.1046/j.1523-1755.2001.00733.x
Autor:
Eiji Masuda, Takaaki Kobayashi, Wataru Hayakawa, Shizuo Yamada, Akihiro Suemasa, Takahiro Katayama, Soichiro Ide, Shuhei Kawamura, Mamie Yoshikawa, Yoshihiko Ito, Kazuaki Nakada, Mitsuhiro Arisawa, Masabumi Minami, Satoshi Shuto
Publikováno v:
Bioorganicmedicinal chemistry. 21(17)
A series of cyclopropane-based conformationally restricted gamma-aminobutyric acid (GABA) analogs with stereochemical diversity, that is, the trans- and cis-2,3-methano analogs Ia and Ib and their enantiomers ent-Ia and ent-Ib, and also the trans- an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8eacd6e63dcbc377ad62486e7faf47
https://pubmed.ncbi.nlm.nih.gov/23886812
https://pubmed.ncbi.nlm.nih.gov/23886812
Autor:
Mouyna, Isabelle, Hartland, Robert P., Fontaine, Thierry, Diaquin, Michel, Simenel, Catherine, Delepierre, Muriel, Henrissat, Bernard, Latgé, Jean-Paul
Publikováno v:
Microbiology
Microbiology, 1998, 144, pp.3171-3180. ⟨10.1099/00221287-144-11-3171⟩
Microbiology, Microbiology Society, 1998, pp.3171-3180. ⟨10.1099/00221287-144-11-3171⟩
Microbiology, 1998, 144, pp.3171-3180. ⟨10.1099/00221287-144-11-3171⟩
Microbiology, Microbiology Society, 1998, pp.3171-3180. ⟨10.1099/00221287-144-11-3171⟩
International audience; A 1,3-beta-glucanosyltransferase which introduces intrachain 1,6-beta linkages into 1,3-beta-glucan was isolated from the cell wall of Aspergillus fumigatus. The biochemical and molecular characterization of the A. fumigatus t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::57342bb5f46feade4234fce051533e52
https://hal-pasteur.archives-ouvertes.fr/pasteur-00372577
https://hal-pasteur.archives-ouvertes.fr/pasteur-00372577