Development of a Novel Clinical Decision Support System for Exercise Prescription Among Patients With Multiple Cardiovascular Disease Risk Factors

Autor: Margaux A. Guidry, Yin Wu, Gregory A. Panza, Linda S. Pescatello, Amanda L. Zaleski

Publikováno v: Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 5, Iss 1, Pp 193-203 (2021)
Mayo Clinic Proceedings: Innovations, Quality & Outcomes

Cardiovascular disease (CVD) risk factors cluster in an individual. Exercise is universally recommended to prevent and treat CVD. Yet, clinicians lack guidance on how to design an exercise prescription (ExRx) for patients with multiple CVD risk facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13441ab88952cea87ec39bf0de22f956
http://www.sciencedirect.com/science/article/pii/S2542454820301570

Metabolic syndrome; associations with adverse outcome after colorectal surgery. A systematic review and meta-analysis

Autor: R.M.H. Roumen, A.G. Lieverse, L. Janssen, C.D. Slooter, G.D. Slooter, M. Reudink

Publikováno v: Annals of Medicine and Surgery

Background Increasing evidence shows that patients with Metabolic Syndrome (MetS) are at risk for adverse outcome after abdominal surgery. The aim of this study was to investigate the impact of MetS and preoperative hyperglycemia, as an individual co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801203450975fe8b9fbd06160cca5f64
https://pubmed.ncbi.nlm.nih.gov/34840752

Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis

Autor: Chengyuan Tang, Xiaofen Xiong, Xiaoxuan Xu, Lin Sun, Shuguang Yuan, Yachun Han, Xianghui Chen, Shikun Yang, Yashpal S. Kanwar, Fuyou Liu, Xuejing Zhu, Ming Yang, Li Xiao, Peng Gao

Publikováno v: Redox Biology
Redox Biology, Vol 16, Iss, Pp 32-46 (2018)

NLRP3/IL-1β activation via thioredoxin (TRX)/thioredoxin-interacting protein (TXNIP) following mitochondria ROS (mtROS) overproduction plays a key role in inflammation. However, the involvement of this process in tubular damage in the kidneys of pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb01cc8d366dba9d9e8efe1eccaf3915
http://europepmc.org/articles/PMC5842313

Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice

Autor: Andras Franko, Hans-Ulrich Häring, Marketa Kovarova, Eckhard Wolf, Annette Feuchtinger, Jan Rozman, Helmut Fuchs, Frauke Neff, Laura Brachthäuser, Birgit Rathkolb, Susanne Neschen, Michaela Aichler, Andreas Peter, Martin Hrabě de Angelis

Publikováno v: Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 3, Pp 256-266 (2017)
Mol. Metab. 6, 256-266 (2017)

Objective Recently, we have shown that Bezafibrate (BEZ), the pan-PPAR (peroxisome proliferator-activated receptor) activator, ameliorated diabetes in insulin deficient streptozotocin treated diabetic mice. In order to study whether BEZ can also impr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b978b4c0d5931dd73645b5c13e5f62ec
http://europepmc.org/articles/PMC5323884

COVID-19 associated with diabetes and other noncommunicable diseases led to a global health crisis

Autor: Simone Bega Harnik, Roque Cardona-Hernandez, Lucas Xavier de Oliveira, Mark Thomaz Ugliara Barone, Luiz Menna-Barreto, Dániel Végh, Nayanjeet Chaudhury, Belinda Ngongo, Hermelinda Cordeiro Pedrosa, Patrícia Vieira de Luca, Franco Giraudo

Publikováno v: Diabetes Research and Clinical Practice
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

COVID-19 has gravely threatened high-risk populations, such as people with diabetes and other noncommunicable diseases, leading to disproportionate hospitalizations, longer and repeated hospital stays and deaths among these individuals worldwide. It

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b61634e7f6c6f7ee3e1902bc60feb24
https://doi.org/10.1016/j.diabres.2020.108587