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pro vyhledávání: '"BETA-AMYLOID PEPTIDE"'
Autor:
Jerel Adam Fields, Mary Swinton, Erin E. Sundermann, Nicholas Scrivens, Kaylie-Anna Juliette Vallee, David J. Moore
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
People with HIV (PWH) continue to suffer from dysfunction of the central nervous system, as evidenced by HIV-associated neurocognitive disorder (HAND), despite antiretroviral therapy and suppressed viral loads. As PWH live longer they may also be at
Externí odkaz:
https://doaj.org/article/4afb9e818e594363b6a4c7323f53ff43
Autor:
DIAO Hua-qiong, LI Xiao-li, LIN Liang-yin, LIU Hai-peng, CHEN Hong-jing, DING Hai-yue, WEI Dan
Publikováno v:
Jichu yixue yu linchuang, Vol 40, Iss 11, Pp 1542-1545 (2020)
Alzheimer's disease is the most common dementia in the aged population and is characterizd by hidden attack and progressive development. Some studies showed that exosomal microRNAs(miRNAs) regulates the shearing of amyloid precusor protein,deposition
Externí odkaz:
https://doaj.org/article/2ee5c0d66e91468fb91e414f298ba743
Autor:
Guido Domingo, Luisa Benussi, Claudia Saraceno, Michela Bertuzzi, Roland Nicsanu, Antonio Longobardi, Sonia Bellini, Alfredo Cagnotto, Mario Salmona, Giuliano Binetti, Roberta Ghidoni
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Alzheimer’s disease (AD) is a pathology characterized by the accumulation in the brain of intracellular and extracellular amyloid-β (Aβ) aggregates, especially of Aβ1–40 and Aβ1–42 peptides. It is known that N-terminally truncated or modifi
Externí odkaz:
https://doaj.org/article/d12cc86340c14def8a5fb846b2682e52
Akademický článek
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Akademický článek
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Publikováno v:
Inorganics, Vol 10, Iss 1, p 6 (2022)
Alzheimer’s disease is a progressive neurodegenerative disorder that eventually leads the affected patients to die. The appearance of senile plaques in the brains of Alzheimer’s patients is known as a main symptom of this disease. The plaques con
Externí odkaz:
https://doaj.org/article/649f965a55314ec4a18c1739510c3251
Autor:
Vyronia Vassilakopoulou, Chrysoula-Evangelia Karachaliou, Alexandra Evangelou, Christos Zikos, Evangelia Livaniou
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1278 (2021)
The development of peptide-based vaccines for treating human neurodegenerative diseases has been the eventual aim of many research endeavors, although no active immunotherapies have been approved for clinical use till now. A typical example of such e
Externí odkaz:
https://doaj.org/article/e02da4c886c148378405191022f9b062
Publikováno v:
Biomolecular Concepts, Vol 8, Iss 1, Pp 37-43 (2017)
Alzheimer’s disease (AD) is a neurodegenerative condition characterized by the formation of amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia and neuronal cell death, ultimately leading to progressive dementia.
Externí odkaz:
https://doaj.org/article/77ea4adf46294e9891b83d695005b723
Akademický článek
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Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Alzheimer’s disease (AD) is a heterogeneous neurodegenerative disease. Recent studies suggest that miRNA expression changes are associated with the development of AD. Our previous study showed that the expression level of miR-409-5p was stably down
Externí odkaz:
https://doaj.org/article/b7cc49c4481d46dd8f1acae998745ddd