Zobrazeno 1 - 10
of 31
pro vyhledávání: '"BERTRAND JE"'
MultiPro: DDA-PASEF and diaPASEF acquired cell line proteomic datasets with deliberate batch effects
Autor:
He Wang, Kai Peng Lim, Weijia Kong, Huanhuan Gao, Bertrand Jern Han Wong, Ser Xian Phua, Tiannan Guo, Wilson Wen Bin Goh
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-11 (2023)
Abstract Mass spectrometry-based proteomics plays a critical role in current biological and clinical research. Technical issues like data integration, missing value imputation, batch effect correction and the exploration of inter-connections amongst
Externí odkaz:
https://doaj.org/article/07c3c211bcf642b5ac75d20d35c89031
Autor:
Rieck Paul, Schaufler Anna, Fritzsche Holger, Bertrand Jessica, Lohmann Christoph, Boese Axel
Publikováno v:
Current Directions in Biomedical Engineering, Vol 8, Iss 2, Pp 481-484 (2022)
Knee arthroplasty follow-up involves only a limited number of X-ray-based implant condition assessments at extended intervals. Polyethylene (PE) wear of knee endoprosthesis often progresses unnoticed until symptomatic adverse effects become apparent
Externí odkaz:
https://doaj.org/article/2146c9f157e9425ab10c394a957d048d
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Despite technological advances in proteomics, incomplete coverage and inconsistency issues persist, resulting in “data holes”. These data holes cause the missing protein problem (MPP), where relevant proteins are persistently unobserved,
Externí odkaz:
https://doaj.org/article/5184e1b7d48a4adda5a3731eb5434c6c
Autor:
Schaufler Anna, Fritzsche Holger, Bertrand Jessica, Lohmann Christoph, Boese Axel, Friebe Michael
Publikováno v:
Current Directions in Biomedical Engineering, Vol 7, Iss 2, Pp 283-286 (2021)
Polyethylene (PE) inlays of knee endoprostheses are exposed to constant mechanical stress causing particle abrasion and volumetric wear. With the current inlay surveillance strategy, significant change often can be only detected when the implant has
Externí odkaz:
https://doaj.org/article/b0ce85a6c2c34c519ddea7098ae491ef
Autor:
Zelu Huang, Weijia Kong, Bertrand Jernhan Wong, Huanhuan Gao, Tiannan Guo, Xianming Liu, Xiaoxian Du, Limsoon Wong, Wilson Wen Bin Goh
Publikováno v:
Data in Brief, Vol 41, Iss , Pp 107919- (2022)
We present four datasets on proteomics profiling of HeLa and SiHa cell lines associated with the research described in the paper “PROTREC: A probability-based approach for recovering missing proteins based on biological networks” [1]. Proteins in
Externí odkaz:
https://doaj.org/article/a6d81644122d41489e1ef14c99b9ba16
Autor:
Sambhavi Animesh, Ruchi Choudhary, Bertrand Jern Han Wong, Charlotte Tze Jia Koh, Xin Yi Ng, Joshua Kai Xun Tay, Wan-Qin Chong, Han Jian, Leilei Chen, Boon Cher Goh, Melissa Jane Fullwood
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Nasopharyngeal cancer (NPC), a cancer derived from epithelial cells in the nasopharynx, is a cancer common in China, Southeast Asia, and Africa. The three-dimensional (3D) genome organization of nasopharyngeal cancer is poorly understood. A major cha
Externí odkaz:
https://doaj.org/article/4961c22232fc4e99a13d55b9b9aa4f7e
Autor:
Anne Mullin, Bertrand Jean-Claude
Publikováno v:
McGill Journal of Medicine, Vol 4, Iss 1 (2020)
Breast tumor cells overexpressing the proto-oncogene HER2/neu are known to be less responsive to certain DNA-binding chemotherapeutic agents. The current study specifically investigates the correlation between chemosensitivity to the DNA-binding drug
Externí odkaz:
https://doaj.org/article/351b4181b44f485faa3dd8f9ef0b9c77
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Mutations of the DNA repair proteins BRCA1/2 are synthetically lethal with the DNA repair enzyme poly(ADP-ribose) polymerase (PARP), which when inhibited, leads to cell death due to the absence of compensatory DNA repair mechanism
Externí odkaz:
https://doaj.org/article/0d2956504c77493290bed63646ccd9c5
Autor:
Benoît Thibault, Bertrand Jean-Claude
Publikováno v:
Journal of Ovarian Research, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Background Ovarian cancer is the leading cause of death for gynecological cancers and the 6th cause of women cancer death in developed countries. The late stage detection, the peritoneal dissemination and the acquisition of resistance agains
Externí odkaz:
https://doaj.org/article/82074462559c45f6a8eb6d0880028eaa
Autor:
Paul Daniel, Siham Sabri, Ahmad Chaddad, Brian Meehan, Bertrand Jean-Claude, Janusz Rak, Bassam S. Abdulkarim
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Glioma are the most common type of malignant brain tumor, with glioblastoma (GBM) representing the most common and most lethal type of glioma. Surgical resection followed by radiotherapy and chemotherapy using the alkylating agent Temozolomide (TMZ)
Externí odkaz:
https://doaj.org/article/11365748e5fb420c90b63cf3529b6f11