Structure-based targeting of the lipid A-modifying enzyme PmrC to contrast colistin resistance in Acinetobacter baumannii .

Autor: Romano M; Department of Biomedical Sciences, Institute of Biostructures and Bioimaging, National Research Council (CNR), Napoli, Italy., Falchi F; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Bologna, Italy.; Computational and Chemical Biology, Italian Institute of Technology, Genova, Italy., De Gregorio E; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy., Stabile M; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy., Migliaccio A; Department of Public Health, University of Naples Federico II, Naples, Italy., Ruggiero A; Department of Biomedical Sciences, Institute of Biostructures and Bioimaging, National Research Council (CNR), Napoli, Italy., Napolitano V; Department of Biomedical Sciences, Institute of Biostructures and Bioimaging, National Research Council (CNR), Napoli, Italy., Autiero I; Department of Biomedical Sciences, Institute of Biostructures and Bioimaging, National Research Council (CNR), Napoli, Italy., Squeglia F; Department of Biomedical Sciences, Institute of Biostructures and Bioimaging, National Research Council (CNR), Napoli, Italy., Berisio R; Department of Biomedical Sciences, Institute of Biostructures and Bioimaging, National Research Council (CNR), Napoli, Italy.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2024 Nov 28; Vol. 15, pp. 1501051. Date of Electronic Publication: 2024 Nov 28 (Print Publication: 2024).

A rationally designed antigen elicits protective antibodies against multiple nosocomial Gram-positive pathogens.

Autor: Kramarska E; Institute of Biostructures and Bioimaging, Italian Research Council (CNR), Naples, Italy., Toumi E; CNRS, INSERM, Institut Necker-Enfants Malades, U1151-Equipe 11, Faculté de Médecine, University of Paris City, Paris, France., Squeglia F; Institute of Biostructures and Bioimaging, Italian Research Council (CNR), Naples, Italy., Laverde D; Division of Paediatric Infectious Disease, Hauner Children's Hospital LMU, LMU, Munich, Germany., Napolitano V; Institute of Biostructures and Bioimaging, Italian Research Council (CNR), Naples, Italy., Frapy E; CNRS, INSERM, Institut Necker-Enfants Malades, U1151-Equipe 11, Faculté de Médecine, University of Paris City, Paris, France., Autiero I; Institute of Biostructures and Bioimaging, Italian Research Council (CNR), Naples, Italy., Sadones O; Division of Paediatric Infectious Disease, Hauner Children's Hospital LMU, LMU, Munich, Germany., Huebner J; Division of Paediatric Infectious Disease, Hauner Children's Hospital LMU, LMU, Munich, Germany., Skurnik D; CNRS, INSERM, Institut Necker-Enfants Malades, U1151-Equipe 11, Faculté de Médecine, University of Paris City, Paris, France. david.skurnik@inserm.fr.; Department of Clinical Microbiology, Fédération Hospitalo-Universitaire Prématurité (FHU PREMA), Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University of Paris City, Paris, France. david.skurnik@inserm.fr.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. david.skurnik@inserm.fr., Romero-Saavedra F; Division of Paediatric Infectious Disease, Hauner Children's Hospital LMU, LMU, Munich, Germany. felipe.romero@med.uni-muenchen.de., Berisio R; Institute of Biostructures and Bioimaging, Italian Research Council (CNR), Naples, Italy. rita.berisio@cnr.it.

Publikováno v: NPJ vaccines [NPJ Vaccines] 2024 Aug 18; Vol. 9 (1), pp. 151. Date of Electronic Publication: 2024 Aug 18.

HtpG-A Major Virulence Factor and a Promising Vaccine Antigen against Mycobacterium tuberculosis .

Autor: Berisio R; Institute of Biostructures and Bioimaging, IBB, CNR, Via Pietro Castellino 111, I-80131 Naples, Italy., Barra G; Institute of Biostructures and Bioimaging, IBB, CNR, Via Pietro Castellino 111, I-80131 Naples, Italy., Napolitano V; Institute of Biostructures and Bioimaging, IBB, CNR, Via Pietro Castellino 111, I-80131 Naples, Italy., Privitera M; Institute of Biostructures and Bioimaging, IBB, CNR, Via Pietro Castellino 111, I-80131 Naples, Italy., Romano M; Institute of Biostructures and Bioimaging, IBB, CNR, Via Pietro Castellino 111, I-80131 Naples, Italy., Squeglia F; Institute of Biostructures and Bioimaging, IBB, CNR, Via Pietro Castellino 111, I-80131 Naples, Italy., Ruggiero A; Institute of Biostructures and Bioimaging, IBB, CNR, Via Pietro Castellino 111, I-80131 Naples, Italy.

Publikováno v: Biomolecules [Biomolecules] 2024 Apr 11; Vol. 14 (4). Date of Electronic Publication: 2024 Apr 11.

Klebsiella phage KP34gp57 capsular depolymerase structure and function: from a serendipitous finding to the design of active mini-enzymes against K. pneumoniae .

Autor: Maciejewska B; Department of Pathogen Biology and Immunology, University of Wrocław , Wrocław, Poland., Squeglia F; Institute of Biostructures and Bioimaging, CNR , Napoli, Italy., Latka A; Department of Pathogen Biology and Immunology, University of Wrocław , Wrocław, Poland., Privitera M; Institute of Biostructures and Bioimaging, CNR , Napoli, Italy., Olejniczak S; Department of Pathogen Biology and Immunology, University of Wrocław , Wrocław, Poland., Switala P; Department of Pathogen Biology and Immunology, University of Wrocław , Wrocław, Poland., Ruggiero A; Institute of Biostructures and Bioimaging, CNR , Napoli, Italy., Marasco D; Department of Pharmacy, University of Naples Federico II , Napoli, Italy., Kramarska E; Institute of Biostructures and Bioimaging, CNR , Napoli, Italy., Drulis-Kawa Z; Department of Pathogen Biology and Immunology, University of Wrocław , Wrocław, Poland., Berisio R; Institute of Biostructures and Bioimaging, CNR , Napoli, Italy.

Publikováno v: MBio [mBio] 2023 Oct 31; Vol. 14 (5), pp. e0132923. Date of Electronic Publication: 2023 Sep 14.

Structural Basis of PE_PGRS Polymorphism, a Tool for Functional Modulation.

Autor: Kramarska E; Institute of Biostructures and Bioimaging, IBB, CNR, 80131 Naples, Italy., De Maio F; Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario 'A. Gemelli', IRCCS, 00168 Rome, Italy., Delogu G; Dipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche E Perioperatorie-Sezione di Microbiologia, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.; Laboratory Medicine, Mater Olbia Hospital, 07026 Olbia, Italy., Berisio R; Institute of Biostructures and Bioimaging, IBB, CNR, 80131 Naples, Italy.

Publikováno v: Biomolecules [Biomolecules] 2023 May 10; Vol. 13 (5). Date of Electronic Publication: 2023 May 10.