Zobrazeno 1 - 10
of 162
pro vyhledávání: '"BEN Ponvilawan"'
Autor:
Yasuo Kubota, Xiaorong Gu, Laila Terkawi, Juraj Bodo, Bartlomiej P. Przychodzen, Hussein Awada, Nakisha Williams, Carmelo Gurnari, Naomi Kawashima, Mai Aly, Arda Durmaz, Minako Mori, Ben Ponvilawan, Tariq Kewan, Waled Bahaj, Manja Meggendorfer, Babal K. Jha, Valeria Visconte, Heesun J. Rogers, Torsten Haferlach, Jaroslaw P. Maciejewski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract PHF6 mutations (PHF6 MT) are identified in various myeloid neoplasms (MN). However, little is known about the precise function and consequences of PHF6 in MN. Here we show three main findings in our comprehensive genomic and proteomic study.
Externí odkaz:
https://doaj.org/article/a86ae8fe55bc46c2af1a9650289584f9
Autor:
Waled Bahaj, Tariq Kewan, Carmelo Gurnari, Arda Durmaz, Ben Ponvilawan, Ishani Pandit, Yasuo Kubota, Olisaemeka D. Ogbue, Misam Zawit, Yazan Madanat, Taha Bat, Suresh K. Balasubramanian, Hussein Awada, Ramsha Ahmed, Minako Mori, Manja Meggendorfer, Torsten Haferlach, Valeria Visconte, Jaroslaw P. Maciejewski
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background TP53 mutations (TP53 MT ) occur in diverse genomic configurations. Particularly, biallelic inactivation is associated with poor overall survival in cancer. Lesions affecting only one allele might not be directly leukemogenic, ques
Externí odkaz:
https://doaj.org/article/be24204f0e834aaeb1aa9535926fa7e7
Autor:
Himil Mahadevia, Ben Ponvilawan, Ammar Al-Obaidi, Jennifer Buckley, Janakiraman Subramanian, Dhruv Bansal
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Immune checkpoint inhibitors (ICIs) and poly (ADP-ribose) polymerase (PARP) inhibitors have shown efficacy in various tumors. A significant therapeutic challenge with either ICIs or PARP inhibitors as monotherapy is treatment failure from intrinsic p
Externí odkaz:
https://doaj.org/article/4fb5286f5f1d46a8a961bf50d89e628a
Autor:
Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Laila Terkawi, Hussein Awada, Olisaemeka D. Ogbue, Ramsha Ahmed, Simona Pagliuca, Hassan Awada, Yasuo Kubota, Minako Mori, Ben Ponvilawan, Bayan Al-Share, Bhumika J. Patel, Hetty E. Carraway, Jacob Scott, Suresh K. Balasubramanian, Taha Bat, Yazan Madanat, Mikkael A. Sekeres, Torsten Haferlach, Valeria Visconte, Jaroslaw P. Maciejewski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Genomic mutations drive the pathogenesis of myelodysplastic syndromes and acute myeloid leukemia. While morphological and clinical features have dominated the classical criteria for diagnosis and classification, incorporation of molecular da
Externí odkaz:
https://doaj.org/article/6c02bbbd75f840c28ae20ecd4c63c506
Publikováno v:
Indian Journal of Dermatology, Vol 68, Iss 4, Pp 359-365 (2023)
Background: Patients with hidradenitis suppurativa (HS) may have a higher risk of coronary artery disease (CAD) due to the excessive inflammatory burden. However, data on this association is still relatively limited. Aims: To investigate the associat
Externí odkaz:
https://doaj.org/article/82ddaaa6a3404aeb9437b80d51f0676e
Autor:
Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Laila Terkawi, Hussein Awada, Olisaemeka D. Ogbue, Ramsha Ahmed, Simona Pagliuca, Hassan Awada, Yasuo Kubota, Minako Mori, Ben Ponvilawan, Bayan Al-Share, Bhumika J. Patel, Hetty E. Carraway, Jacob Scott, Suresh K. Balasubramanian, Taha Bat, Yazan Madanat, Mikkael A. Sekeres, Torsten Haferlach, Valeria Visconte, Jaroslaw P. Maciejewski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/01960e5d4a034cfc8740c0ade2b48edf
Autor:
Arda Durmaz, Carmelo Gurnari, Courtney E. Hershberger, Simona Pagliuca, Noah Daniels, Hassan Awada, Hussein Awada, Vera Adema, Minako Mori, Ben Ponvilawan, Yasuo Kubota, Tariq Kewan, Waled S. Bahaj, John Barnard, Jacob Scott, Richard A. Padgett, Torsten Haferlach, Jaroslaw P. Maciejewski, Valeria Visconte
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106238- (2023)
Summary: RNA splicing dysfunctions are more widespread than what is believed by only estimating the effects resulting by splicing factor mutations (SFMT) in myeloid neoplasia (MN). The genetic complexity of MN is amenable to machine learning (ML) str
Externí odkaz:
https://doaj.org/article/d7344695913646679785ec82bb7788b6
Autor:
Nipith Charoenngam, Jerapas Thongpiya, Pitchaporn Yingchoncharoen, Ben Ponvilawan, Mehmet S. Marangoz, Jirat Chenbhanich, Patompong Ungprasert
Publikováno v:
International Journal of Endocrinology, Vol 2023 (2023)
Objective. To summarize the characteristics of all reported patients with hypophosphatasia (HPP) who sustained atypical femoral fracture (AFF) and identify all available evidence to quantify the rate of coexistence between HPP and AFF. Methods. Poten
Externí odkaz:
https://doaj.org/article/842ff92352cd475286adb24bd7596037
Autor:
Sunisa Prasopporn, Orawan Suppramote, Ben Ponvilawan, Chanette Jamyuang, Jantappapa Chanthercrob, Amphun Chaiboonchoe, Pimkanya More-Krong, Kamonchanok Kongsri, Monthira Suntiparpluacha, Rawisak Chanwat, Krittiya Korphaisarn, Seiji Okada, Somponnat Sampattavanich, Siwanon Jirawatnotai
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/ec0a8457396d49cb9b31dd5bb0eb9d12
Autor:
Sunisa Prasopporn, Orawan Suppramote, Ben Ponvilawan, Chanette Jamyuang, Jantappapa Chanthercrob, Amphun Chaiboonchoe, Pimkanya More-Krong, Kamonchanok Kongsri, Monthira Suntiparpluacha, Rawisak Chanwat, Krittiya Korphaisarn, Seiji Okada, Somponnat Sampattavanich, Siwanon Jirawatnotai
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cholangiocarcinoma (CCA) is a highly lethal gastrointestinal malignancy that has one of the worst prognoses among solid tumors. The combination of Gemcitabine + Cisplatin (GEM/CIS) remains the standard first-line treatment for advanced stage CCA. How
Externí odkaz:
https://doaj.org/article/911c30605c684512880a37fea8fa7666