Zobrazeno 1 - 10
of 105
pro vyhledávání: '"BDP1"'
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 6401-6418 (2023)
Abstract Background TFIIIB, an RNA polymerase III specific transcription factor has been found to be deregulated in human cancers with much of the research focused on the TBP, BRF1, and BRF2 subunits. To date, the TFIIIB specific subunit BDP1 has not
Externí odkaz:
https://doaj.org/article/6f40ed66dad84b2eb6dbd0b5d132d015
Autor:
Xiaoqing Li, Lan Sun, Andres Stucky, Lingli Tu, Jin Cai, Xuelian Chen, Zhongjun Wu, Xuhong Jiang, Shengwen Calvin Li
Publikováno v:
Diagnostics, Vol 11, Iss 12, p 2364 (2021)
Background: Neuroblastoma (N.B.) is the most common tumor in children. The gene BDP1 (B Double Prime 1) plays a role in cancers but is less known in N.B. Thus, we conducted this study to investigate the value of BDP1 mutations in N.B. prognosis. Meth
Externí odkaz:
https://doaj.org/article/2834cb6d264a4c7e830eaf25b7140711
Akademický článek
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Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1658
TFIIIB is deregulated in a variety of cancers. However, few studies investigate the TFIIIB subunit BDP1 in cancer. BDP1 has not been studied in breast cancer patients. Herein, we analyzed clinical breast cancer datasets to determine if BDP1 alteratio
Publikováno v:
BioMedInformatics; Volume 2; Issue 1; Pages: 169-183
The RNA polymerase III–specific TFIIIB complex is targeted by oncogenes and tumor suppressors, specifically the TFIIIB subunits BRF1, BRF2, and TBP. Currently, it is unclear if the TFIIIB subunit BDP1 is universally deregulated in human cancers. We
Autor:
Fiordaliso C. Román-Carraro, Julio César Carrero, Gabriela Romero-Meza, Rossana Arroyo, Santiago Martínez-Calvillo, Tomás Nepomuceno-Mejía, Luis E. Florencio-Martínez, Jaime Ortega-López, Rebeca Manning-Cela
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2019 (2019)
BioMed Research International, Vol 2019 (2019)
Leishmania major, a protozoan parasite that diverged early from the main eukaryotic lineage, exhibits unusual mechanisms of gene expression. Little is known in this organism about the transcription factors involved in the synthesis of tRNA, 5S rRNA,
Publikováno v:
The FASEB Journal. 35
Autor:
Santiago Martínez-Calvillo, Rebeca Manning-Cela, Carlos Flores-Pérez, Luis E. Florencio-Martínez, Fiordaliso C. Román-Carraro, Luis A. Barocio-Rodríguez, Tomás Nepomuceno-Mejía, Andrés Cano-Santiago, Fabiola Mondragón-Rosas, Maricarmen Gómez-García
Publikováno v:
Genes
Volume 12
Issue 2
Genes, Vol 12, Iss 280, p 280 (2021)
Volume 12
Issue 2
Genes, Vol 12, Iss 280, p 280 (2021)
In yeast and higher eukaryotes, transcription factor TFIIIB is required for accurate initiation of transcription by RNA Polymerase III (Pol III), which synthesizes transfer RNAs (tRNAs), 5S ribosomal RNA (rRNA), and other essential RNA molecules. TFI
Akademický článek
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Publikováno v:
Nucleic Acids Research
Transcription of transfer RNA genes by RNA polymerase III (Pol III) is controlled by general factors, TFIIIB and TFIIIC, and a negative regulator, Maf1. Here we report the interplay between TFIIIC and Maf1 in controlling Pol III activity upon the phy