Zobrazeno 1 - 10
of 223
pro vyhledávání: '"BCR/ABL1"'
Autor:
Sharanjit Singh Toor, Paresh Singhal
Publikováno v:
Medical Journal of Dr. D.Y. Patil Vidyapeeth, Vol 16, Iss 3, Pp 459-461 (2023)
Pediatric chronic myeloid leukemia (CML) is rare and has a worse prognosis compared to adult CML. Median age of diagnosis in pediatric age group is 14 years with most cases occurring in children above 12 years of age in India. We report a case of a 2
Externí odkaz:
https://doaj.org/article/65b09011a7b548bd99b2113efc6b5aeb
Autor:
Aleksandra Mroczkowska, Bożena Jaźwiec, Justyna Urbańska-Rakus, Sylwia Szymanowska, Anna Tessmann, Sonia Pająk, Katarzyna Machnik, Olga Haus, Tomasz Wróbel
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract Background Acute lymphoblastic leukemia is the most common type of cancer in children. Most often it affects the age group between 2 and 5 years of age. Studies have shown an improvement in general survivability, more than 90% 5-year overall
Externí odkaz:
https://doaj.org/article/87712a2a48e542f9a09b26db8eb3cb6d
Autor:
Vivek Singh, Ranjana Singh, Rashmi Kushwaha, Shailendra Prasad Verma, Anil Kumar Tripathi, Abbas Ali Mahdi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Chronic myeloid leukemia (CML) is potentially fatal blood cancer, but there is an unmet need to discover novel molecular biomarkers. The hypothesis of this study aimed to elucidate the relationship of HIF1α with the redox system, Krebs cycles, notch
Externí odkaz:
https://doaj.org/article/f339c25bf0eb4837aa7c2489e1d5747f
Autor:
Walid Dridi, Solaf Kanfar, Patrick M. A. Sleiman, Yichuan Liu, Hakon Hakonarson, Hayaal Rammah, Alia Matrouk
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract Background The vast majority of chronic myeloid leukemia (CML) patients have a single translocation t(9;22)(q34;q11), BCR/ABL1 fusion genes, which is regarded as the hallmark of CML. However, around 5 to 10% of CML patients exhibit the invol
Externí odkaz:
https://doaj.org/article/47cfbb22d1994674b0f8e653180e22eb
Autor:
Y.C. Castro, R. Utrera
Publikováno v:
BAG. Journal of Basic and Applied Genetics, Vol 31, Iss 1, Pp 33-43 (2020)
Acute Lymphoblastic Leukemia (ALL) is the most common neoplasm in pediatric age. In recent years, between 15 and 20% of patients failed in their treatments. Knowledge on cytogenetics and molecular biology has an important impact on the determination
Externí odkaz:
https://doaj.org/article/d073ff6e54ba4afdb88685891b4a1e23
Akademický článek
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Publikováno v:
Therapeutics and Clinical Risk Management, Vol Volume 13, Pp 1159-1162 (2017)
Zhihe Liu,1 Siyun Li,2 Ou Bai1 1Department of Hematology, The First Hospital of Jilin University, Changchun, 2Department of Pediatrics, Women and Children’s hospital of Qingdao university, Qingdao, People’s Republic of China Abstract: We present
Externí odkaz:
https://doaj.org/article/eb6fb09dbb654278b18275d12df1407b
Autor:
Elena Vuelta, Ignacio García-Tuñón, Patricia Hernández-Carabias, Lucía Méndez, Manuel Sánchez-Martín
Publikováno v:
Biology, Vol 10, Iss 2, p 118 (2021)
The constitutively active tyrosine-kinase BCR/ABL1 oncogene plays a key role in human chronic myeloid leukemia development and disease maintenance, and determines most of the features of this leukemia. For this reason, tyrosine-kinase inhibitors are
Externí odkaz:
https://doaj.org/article/5978d12781ee46f9be1186ac44cddf38
Autor:
Štěpán Hrabovský, Cyril Šálek, Pavla Pecherkova, Petr Cetkovský, Hana Jelínková, Eva Froňková, František Folber, Michael Doubek, Jiří Mayer, Jan Trka, Jan M. Horáček
Publikováno v:
British Journal of Haematology. 196:706-710
The aim of the present study was to evaluate the significance of low-level minimal/measurable residual disease (MRD) during early consolidation treatment in adult BCR-ABL1-negative acute lymphoblastic leukaemia. The MRD load was monitored by immunogl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc6c60c5dbdc66fb92c90784b37990a
https://doi.org/10.1111/bjh.17966
https://doi.org/10.1111/bjh.17966
Autor:
Ayman Qasrawi, Ranjana Arora
Publikováno v:
Advances in Molecular Pathology. 4:65-79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::674bb1b6e822ab3bf7113883ecf0e43c
https://doi.org/10.1016/j.yamp.2021.06.001
https://doi.org/10.1016/j.yamp.2021.06.001