Zobrazeno 1 - 10
of 137
pro vyhledávání: '"BCL2A1"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract The antiapoptotic protein BCL2A1 is highly, but very heterogeneously expressed in Diffuse Large B-cell Lymphoma (DLBCL). Particularly in the context of resistance to current therapies, BCL2A1 appears to play an important role in protecting c
Externí odkaz:
https://doaj.org/article/4e919351ac654b7faa7836358a215e7f
Autor:
Juanfeng Li, Lulu Sun, Fujie Xie, Tianren Shao, Shanbo Wu, Xiaoying Li, Longxian Zhang, Rongjun Wang
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-9 (2023)
Abstract Background Cryptosporidium is second only to rotavirus as a cause of moderate-to-severe diarrhea in young children. There are currently no fully effective drug treatments or vaccines for cryptosporidiosis. MicroRNAs (miRNAs) are involved in
Externí odkaz:
https://doaj.org/article/5fc7e48e51194cd08c594a9f993f9a19
Akademický článek
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Autor:
Fang Liu, RunSang Pan, HongYu Ding, LiLing Gu, Yun Yang, ChuanYin Li, YongJie Xu, Ronggui Hu, Hui Chen, XiangYan Zhang, YingJie Nie
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3738-3752 (2021)
ATM serine/threonine kinase (ATM; previously known as ataxia‐telangiectasia mutated) plays a critical role in maintaining genomic stability and regulates multiple downstream pathways, such as DNA repair, cell cycle arrest, and apoptosis. As a serin
Externí odkaz:
https://doaj.org/article/c30d625dab974349afe266e11ed47685
Akademický článek
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Autor:
Yalan Dai, Liqiong Yang, Abass Sakandar, Duoli Zhang, Fukuan Du, Xinyi Zhang, Linglin Zou, Yueshui Zhao, Jigang Wang, Zhenhua Zhang, Xu Wu, Mingxing Li, Xiao Ling, Lei Yu, Lishu Dong, Jing Shen, Zhangang Xiao, Qinglian Wen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectivesTo investigate the role of immune escape encoding genes on the prognosis of BC, and to predict the novel targeting agents.MethodsHuman immune genes and immune escape encoding genes were obtained from the IMMPORT database and the previous st
Externí odkaz:
https://doaj.org/article/edba98d7eb8d48febb7c1100e53bef0c
Akademický článek
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Autor:
Özden Hatırnaz Ng, Ahmet Emre Eşkazan
Publikováno v:
Translational Oncology, Vol 19, Iss , Pp 101394- (2022)
Externí odkaz:
https://doaj.org/article/1f528354e1434084a674eb15577ef571
Autor:
Kotoko Yamatani, Tomohiko Ai, Kaori Saito, Koya Suzuki, Atsushi Hori, Sonoko Kinjo, Kazuho Ikeo, Vivian Ruvolo, Weiguo Zhang, Po Yee Mak, Bogumil Kaczkowski, Hironori Harada, Kazuhiro Katayama, Yoshikazu Sugimoto, Jered Myslinski, Takashi Hato, Takashi Miida, Marina Konopleva, Yoshihide Hayashizaki, Bing Z. Carter, Yoko Tabe, Michael Andreeff
Publikováno v:
Translational Oncology, Vol 18, Iss , Pp 101354- (2022)
Tyrosine kinase inhibitors (TKIs) are established drugs in the therapy of FLT3-ITD mutated acute myeloid leukemia (AML). However, acquired mutations, such as D835 in the tyrosine kinase domain (FLT3-ITD/D835), can induce resistance to TKIs. A cap ana
Externí odkaz:
https://doaj.org/article/5f829a8f3d514045bac9ac8ddf376118
Autor:
Taohua Yue, Xiangzheng Liu, Shuai Zuo, Jing Zhu, Jichang Li, Yucun Liu, Shanwen Chen, Pengyuan Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Background: Cisplatin enhances the antitumor T cell response, and the combination of PD-L1 blockade produces a synergistic therapeutic effect. However, the clinical correlation between cisplatin and immunotherapy in colon cancer (CC) is unknown.Metho
Externí odkaz:
https://doaj.org/article/6b715d89964a48e9834de6c6b7962be2