Zobrazeno 1 - 10
of 50
pro vyhledávání: '"BCAA, branched chain amino acids"'
Autor:
John W. Elrod, Steven R. Houser, Markus Wallner, Remus M. Berretta, Dhanendra Tomar, Anh T Huynh, Joanne F Garbincius, Deborah M Eaton, Emma K Murray, Devin W. Kolmetzky, Andrew A. Gibb
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Early cardiac mitochondrial dysfunction is mediated by transcriptional down-regulation of the mitochondrial proteome. • Comprehensive metabolic remodeling is conserved throughout HFpEF progression and includes in
Highlights • Early cardiac mitochondrial dysfunction is mediated by transcriptional down-regulation of the mitochondrial proteome. • Comprehensive metabolic remodeling is conserved throughout HFpEF progression and includes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474acd63270db1077349e2d878112f6b
https://doi.org/10.1016/j.jacbts.2021.07.004
https://doi.org/10.1016/j.jacbts.2021.07.004
Publikováno v:
Journal of Exercise Science and Fitness
Journal of Exercise Science & Fitness, Vol 18, Iss 3, Pp 155-161 (2020)
Journal of Exercise Science & Fitness, Vol 18, Iss 3, Pp 155-161 (2020)
Background/Objectives: The present study aimed to investigate the effects of three solutions, i.e. carbohydrate-electrolyte-solution (CES), carbohydrate-electrolyte-protein-solution (CEPS), and placebo (PLA), on cognitive function of college soccer p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ac555a4460ccd2df487831b3c16f69
http://europepmc.org/articles/PMC7330616
http://europepmc.org/articles/PMC7330616
Autor:
M. Breederveld, N Ahmadi Mozafari, Johannes H.M. Levels, Mirjam Langeveld, Mark Davids, J.G. Langendonk, C. Timmer, Max Nieuwdorp
Publikováno v:
Molecular genetics and metabolism reports, 29:100794. Elsevier BV
Molecular Genetics and Metabolism Reports, Vol 29, Iss, Pp 100794-(2021)
Molecular Genetics and Metabolism Reports, 29:100794. Elsevier
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 29, Iss, Pp 100794-(2021)
Molecular Genetics and Metabolism Reports, 29:100794. Elsevier
Molecular Genetics and Metabolism Reports
Urea cycle disorders (UCDs) are a group of rare inherited metabolic diseases causing hyperammonemic encephalopathy. Despite intensive dietary and pharmacological therapy, outcome is poor in a subset of UCD patients. Reducing ammonia production by cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d52893a52c18903ec2665d11b82070
https://pure.amc.nl/en/publications/differences-in-faecal-microbiome-composition-between-adult-patients-with-ucd-and-pku-and-healthy-control-subjects(8b172534-1d02-4ab8-b0a4-088245e4f97d).html
https://pure.amc.nl/en/publications/differences-in-faecal-microbiome-composition-between-adult-patients-with-ucd-and-pku-and-healthy-control-subjects(8b172534-1d02-4ab8-b0a4-088245e4f97d).html
Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus
Autor:
Michael Rothe, Florian Flenkenthaler, Eckhard Wolf, Martin Hrabĕ de Angelis, Rüdiger Wanke, Jerzy Adamski, Georg J. Arnold, Helmut Blum, Julia Philippou-Massier, Stefan Krebs, Michal Grzybek, Mattias Backman, Maik Dahlhoff, Simone Renner, Erik Ländström, Ünal Coskun, Birgit Rathkolb, Thomas Fröhlich, Cornelia Prehn, Andreas Blutke
Publikováno v:
Molecular Metabolism
Mol. Metab. 26, 30-44 (2019)
Molecular Metabolism, Vol 26, Iss, Pp 30-44 (2019)
Mol. Metab. 26, 30-44 (2019)
Molecular Metabolism, Vol 26, Iss, Pp 30-44 (2019)
Objective The liver regulates the availability of insulin to other tissues and is the first line insulin response organ physiologically exposed to higher insulin concentrations than the periphery. Basal insulin during fasting inhibits hepatic glucone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7e5c3953bcd2186340c014cd2aff9c
http://europepmc.org/articles/PMC6667734
http://europepmc.org/articles/PMC6667734
Autor:
Elisa Enriquez-Hesles, Margaret B. Wierman, Ryan D. Fine, Sean M. Santos, Daniel L. Smith, Nazif Maqani, James R. Bain, Agata Kalita, Matthew D. Hirschey, Matthew D. Sutcliffe, Jeffrey S. Smith, John L. Hartman, Kevin A. Janes, Michael J. Muehlbauer
Publikováno v:
The Journal of Biological Chemistry
Caloric restriction (CR) improves health span and life span of organisms ranging from yeast to mammals. Understanding the mechanisms involved will uncover future interventions for aging-associated diseases. In budding yeast, Saccharomyces cerevisiae,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c7c1c9266dc964189fb3241f15bac4
https://pubmed.ncbi.nlm.nih.gov/33243834
https://pubmed.ncbi.nlm.nih.gov/33243834
Autor:
Daniel J. Wilkinson, Matthew S. Brook, Paula J. Scaife, B.E. Phillips, Jessica Cegielski, Joseph J. Bass, S. Watanabe, Philip J. Atherton, Kenneth Smith
Publikováno v:
Clinical Nutrition (Edinburgh, Scotland)
Summary Background & aims Nutritional composition is key for skeletal muscle maintenance into older age. Yet the acute effects of collagen protein blended with other protein sources, in relation to skeletal muscle anabolism, are ill-defined. We inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622ff8500f657143e7572b97920580a7
https://pubmed.ncbi.nlm.nih.gov/33487503
https://pubmed.ncbi.nlm.nih.gov/33487503
Autor:
Chen Shao, Shaoqing Liu, Lin Liu, Ping Yuan, Zhe Wang, Jianmin Zhang, Feng Zhu, Huimin Sun, Fanfan Zeng, Ruijuan Xiu, Jianyong Zheng, Wei Yan, Qiuhong Duan, Juanjuan Xiao, Olesya S. Malyarenko, Hui Lu, Linni Fan, Peipei Xue
Publikováno v:
EBioMedicine, Vol 20, Iss C, Pp 50-60 (2017)
EBioMedicine
EBioMedicine
Branched-chain amino acids catabolism plays an important role in human cancers. Colorectal cancer is the third most commonly diagnosed cancer in males and the second in females, and the new global incidence is over 1.2 million cases. The branched-cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce432014b6e68ed8eef5d2abe3680daa
https://doi.org/10.1016/j.ebiom.2017.05.001
https://doi.org/10.1016/j.ebiom.2017.05.001
Sarcopenia is an important burden in liver cirrhosis representing a negative prognostic factor for mortality. Moreover, sarcopenia is an independent predictor of complications in patients with liver cirrhosis, including Hepatic Encephalopathy (HE). A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdcca7b777bd9ee4f9f5f7e542c990f0
http://hdl.handle.net/11573/1281304
http://hdl.handle.net/11573/1281304
Autor:
Mary Anne D. Chiong, Esphie Grace D. Fodra, Cristine P. Lopez, Marilyn Tan, Leslie Michelle M. Dalmacio, Cynthia P. Cordero, Judy S. Manliguis
Publikováno v:
Molecular Genetics and Metabolism Reports
Background Maple syrup urine disease (MSUD) is the most common inborn error of metabolism in the country. The cause of the neuropathology is still not well established although accumulation of branched chain amino acids (BCAA) and alteration in large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f439c29a11ac4f5a21961b85117f94a7
https://doi.org/10.1016/j.ymgmr.2016.10.004
https://doi.org/10.1016/j.ymgmr.2016.10.004
Autor:
Gülen Arslan Lied, Ingeborg Brønstad, Einar Lied, Jan Gunnar Hatlebakk, Hanna Fjeldheim Dale, Caroline Jensen, Trygve Hausken, Dag Arne Lihaug Hoff
Publikováno v:
Journal of Nutritional Science
The increased prevalence of lifestyle diseases, such as the metabolic syndrome and type 2 diabetes mellitus (T2DM), calls for more knowledge on dietary treatments targeting the specific metabolic pathways involved in these conditions. Several studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd48703f0a3eaa8a0a50020a4009f2f
http://hdl.handle.net/11250/2593662
http://hdl.handle.net/11250/2593662