Alzheimer's Disease Prevention through Natural Compounds: Cell- Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity

Autor: Palmioli, Alessandro, Mazzoni, Valeria, De Luigi, Ada, Bruzzone, Chiara, Sala, Gessica, Colombo, Laura, Bazzini, Chiara, Zoia, Chiara Paola, Inserra Maria Giovanna, Salmona, Mario, De Noni, Ivano, Ferrarese, Carlo, Diomede, Luisa, Airoldi, Cristina

The relevant social and economic costs associated with aging and neurodegenerative diseases, particularly Alzheimer’s disease (AD), entail considerable efforts to develop effective preventive and therapeutic strategies. The search for natural compo

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STUDY OF MOLECULAR MECHANISMS AND NEW STRATEGIES AGAINST A CYTOTOXICITY AND NEUROINFLAMMATION IN EX VIVO CELLULAR MODELS FROM ALZHEIMER’S DISEASE PATIENTS

Autor: BAZZINI, CHIARA

La malattia di Alzheimer (AD) rappresenta una delle principali problematiche per la salute pubblica ed è stata identificata come una priorità per la ricerca. Le due caratteristiche patologiche fondamentali della malattia sono le placche amiloidi e

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http://hdl.handle.net/10281/306480

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Alzheimer's Disease Prevention through Natural Compounds: Cell-Free , In Vitro , and In Vivo Dissection of Hop ( Humulus lupulus L.) Multitarget Activity.

Autor: Palmioli A; Department of Biotechnology and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126 Milan, Italy.; NeuroMI, Milan Center for Neuroscience, University of Milano-Bicocca, 20126 Milano, Italy., Mazzoni V; Department of Biotechnology and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126 Milan, Italy., De Luigi A; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via M. Negri 2, 20156 Milano, Italy., Bruzzone C; Department of Biotechnology and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126 Milan, Italy., Sala G; NeuroMI, Milan Center for Neuroscience, University of Milano-Bicocca, 20126 Milano, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, Italy., Colombo L; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via M. Negri 2, 20156 Milano, Italy., Bazzini C; NeuroMI, Milan Center for Neuroscience, University of Milano-Bicocca, 20126 Milano, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, Italy., Zoia CP; NeuroMI, Milan Center for Neuroscience, University of Milano-Bicocca, 20126 Milano, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, Italy., Inserra M; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via M. Negri 2, 20156 Milano, Italy., Salmona M; NeuroMI, Milan Center for Neuroscience, University of Milano-Bicocca, 20126 Milano, Italy., De Noni I; Department of Food, Environmental and Nutritional Sciences, University of Milano, Via Celoria 2, 20133 Milano, Italy., Ferrarese C; NeuroMI, Milan Center for Neuroscience, University of Milano-Bicocca, 20126 Milano, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, Italy.; Department of Neuroscience, San Gerardo Hospital, ASST-Monza, Via Pergolesi 33, 20900 Monza, MB, Italy., Diomede L; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via M. Negri 2, 20156 Milano, Italy., Airoldi C; Department of Biotechnology and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126 Milan, Italy.; NeuroMI, Milan Center for Neuroscience, University of Milano-Bicocca, 20126 Milano, Italy.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2022 Nov 16; Vol. 13 (22), pp. 3152-3167. Date of Electronic Publication: 2022 Oct 25.