Zobrazeno 1 - 10
of 555
pro vyhledávání: '"BATF"'
BATF promotes tumor progression and association with FDG PET-derived parameters in colorectal cancer
Autor:
Xia Lu, Jun Liu, Lijuan Feng, Yan Huang, Yanfeng Xu, Cuicui Li, Wei Wang, Yin Kan, Jigang Yang, Mingyu Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Purpose The purpose of the study was to evaluate the expression and function of basic leucine zipper ATF-like transcription factor (BATF) in colorectal cancer (CRC), and its correlation with 2-deoxy-2[18F]fluoro-d-glucose (18F-FDG) positron
Externí odkaz:
https://doaj.org/article/8d60bc54c6a54ea78cd9f84d69618c40
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Background It is well-established that CD8+ T-cells play a critical role in graft rejection. The basic leucine zipper ATF-like transcription factor (BATF) and BATF3 are transcriptional factors expressed in T lymphocytes. Herein, we investiga
Externí odkaz:
https://doaj.org/article/414295795cc444c689fddaa887266c20
Autor:
Bidisha Mitra, Nina Rose Beri, Rui Guo, Eric M. Burton, Laura A. Murray-Nerger, Benjamin E. Gewurz
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTThe Epstein-Barr virus (EBV) oncogene latent membrane protein 1 (LMP1) mimics CD40 signaling and is expressed by multiple malignancies. Two LMP1 C-terminal cytoplasmic tail regions, termed transformation essential sites (TES) 1 and 2, are cri
Externí odkaz:
https://doaj.org/article/44232506b0514188a0d10b641da56aad
Autor:
Achia Khatun, Xiaopeng Wu, Fu Qi, Kexin Gai, Arjun Kharel, Matthew R. Kudek, Lisa Fraser, Ashley Ceicko, Moujtaba Y. Kasmani, Amber Majnik, Robert Burns, Yi‐Guang Chen, Nita Salzman, Elizabeth J. Taparowsky, Dayu Fang, Calvin B. Williams, Weiguo Cui
Publikováno v:
Advanced Science, Vol 10, Iss 28, Pp n/a-n/a (2023)
Abstract Regulatory T (Treg) cells are inevitable to prevent deleterious immune responses to self and commensal microorganisms. Treg function requires continuous expression of the transcription factor (TF) FOXP3 and is divided into two major subsets:
Externí odkaz:
https://doaj.org/article/786eb5c93e3443a6b323cd0698684eb8
Autor:
Zhiwang Zhang, Qichao Liao, Tingli Pan, Lin Yu, Zupeng Luo, Songtao Su, Shi Liu, Menglong Hou, Yixing Li, Turtushikh Damba, Yunxiao Liang, Lei Zhou
Publikováno v:
eLife, Vol 12 (2023)
The rising prevalence of nonalcoholic fatty liver disease (NAFLD) has become a global health threat that needs to be addressed urgently. Basic leucine zipper ATF-like transcription factor (BATF) is commonly thought to be involved in immunity, but its
Externí odkaz:
https://doaj.org/article/c9789a99426341c5a7b84a3476f1e585
Autor:
Chiranjeevi Tikka, Lindsay Beasley, Chengxian Xu, Jing Yang, Scott Cooper, Joseph Lechner, Sarah Gutch, Mark H. Kaplan, Maegan Capitano, Kai Yang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Bone marrow Treg cells (BM Tregs) orchestrate stem cell niches crucial for hematopoiesis. Yet little is known about the molecular mechanisms governing BM Treg homeostasis and function. Here we report that the transcription factor BATF maintains homeo
Externí odkaz:
https://doaj.org/article/7fd38ae17eba4226b0de116f3e19bac0
Akademický článek
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Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Preston R. Arnold, Mou Wen, Lei Zhang, Yuanlin Ying, Xiang Xiao, Xiufeng Chu, Guangchuan Wang, Xiaolong Zhang, Zhuyun Mao, Aijun Zhang, Dale J. Hamilton, Wenhao Chen, Xian C. Li
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
FOXP3 is the lineage-defining transcription factor for Tregs, a cell type critical to immune tolerance, but the mechanisms that control FOXP3 expression in Tregs remain incompletely defined, particularly as it relates to signals downstream of TCR and
Externí odkaz:
https://doaj.org/article/fc9e013cdb234eff8ca5aa5ede160916