Zobrazeno 1 - 10
of 142
pro vyhledávání: '"BAOZHEN ZHANG"'
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110882- (2024)
Summary: P16INK4A expression is inversely associated with RB1 expression in cancer cells, and P16INK4A inhibits CDK4-catalyzed RB1 phosphorylation. How P16INK4A and RB1 coordinately express and regulate the cell cycle remains to be studied. In the pr
Externí odkaz:
https://doaj.org/article/399a45d6120041298ec7054121fe3060
Autor:
Jianhong Liao, Hong Pan, Guojun Huang, Han Gong, Ze Chen, Ting Yin, Baozhen Zhang, Tingtao Chen, Mingbin Zheng, Lintao Cai
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114086- (2024)
Summary: Immune checkpoint blockade (ICB) has revolutionized cancer therapy but only works in a subset of patients due to the insufficient infiltration, persistent exhaustion, and inactivation of T cells within a tumor. Herein, we develop an engineer
Externí odkaz:
https://doaj.org/article/876fcd97686a4b3c85fe5868addd26b2
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Colorectal cancer (CRC) is one of the most common and malignant carcinomas. Many long noncoding RNAs (lncRNAs) have been reported to play important roles in the tumorigenesis of CRC by influencing the expression of some mRNAs via competing e
Externí odkaz:
https://doaj.org/article/4fd458a8617c41b5830291e39cf40153
Autor:
Wei Tian, Hongfan Yuan, Sisi Qin, Wensu Liu, Baozhen Zhang, Liankun Gu, Jing Zhou, Dajun Deng
Publikováno v:
Molecular Oncology, Vol 16, Iss 17, Pp 3192-3209 (2022)
It is well known that the Kaiso protein (encoded by the ZBTB33 gene) is a transcription factor, and Kaiso–P120ctn [P120 catenin (CTNND1)] interaction increases the translocation of Kaiso from the nucleus into the cytoplasm. However, the regulatory
Externí odkaz:
https://doaj.org/article/52a329606d5749a7a4b542407da6d361
Publikováno v:
Shiyou shiyan dizhi, Vol 44, Iss 3, Pp 413-424 (2022)
Taking the influence of lithological characteristics differences on the genesis of pores in migmatite reservoirs as the main line, the genesis and characteristics of pores were analyzed from the perspective of the relationship between rock fabric and
Externí odkaz:
https://doaj.org/article/89011154400e4f5c8939b536a5f8b839
Publikováno v:
Shiyou shiyan dizhi, Vol 44, Iss 2, Pp 270-278 (2022)
The development of micro-nano pores and throats in shale oil reservoirs has made it complicated and diversified for the occurrence and state of oil, and is difficult to be studied. A case study was carried out with the Middle Permian Lucaogou Formati
Externí odkaz:
https://doaj.org/article/bc2f2325b4c34be1961a24c2d02ecb42
Publikováno v:
Shiyou shiyan dizhi, Vol 43, Iss 6, Pp 941-948 (2021)
In order to study the relationship between shale oil production and reservoir porosity or the oil content, experimental approaches including FE-SEM, LSCM, nano CT, high pressure mercury injection and nitrogen adsorption combined analysis, NMR analysi
Externí odkaz:
https://doaj.org/article/62f1eb2e1f504d71beb95de87641e656
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/e7f0787c89af4d8f95aa22f02af1c97f
Autor:
Yuan Tian, Jing Zhou, Juanli Qiao, Zhaojun Liu, Liankun Gu, Baozhen Zhang, Youyong Lu, Rui Xing, Dajun Deng
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundA feasible method to detect somatic copy number deletion (SCND) of genes is still absent to date.MethodsInterstitial base-resolution deletion/fusion coordinates for CDKN2A were extracted from published articles and our whole genome sequenci
Externí odkaz:
https://doaj.org/article/b0ded2b76d0746339b723e454e14f10b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: It is well known that P16INK4A, P14ARF, P15INK4B mRNAs, and ANRIL lncRNA are transcribed from the CDKN2A/2B locus. LncRNA P14AS is a lncRNA transcribed from antisense strand of P14ARF promoter to intron-1. Our previous study showed that P
Externí odkaz:
https://doaj.org/article/5a31450e2db54ef8bb67696d463689ac