Zobrazeno 1 - 10
of 451
pro vyhledávání: '"BAFF-receptor"'
Autor:
JooYeon Jhun, Jeonghyeon Moon, Ji Ye Kwon, Keun-Hyung Cho, Seang Yoon Lee, Hyun Sik Na, Mi-La Cho, Jun-Ki Min
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Rheumatoid arthritis (RA) is an autoimmune disease that causes joint swelling and inflammation and can involve the entire body. RA is characterized by the increase of pro-inflammatory cytokines such as interleukin (IL) and tumor necrosis fac
Externí odkaz:
https://doaj.org/article/173ad8f7b5f74ca58e9e284765cac4db
Autor:
Dario Bruno, Barbara Tolusso, Gianmarco Lugli, Clara Di Mario, Luca Petricca, Simone Perniola, Laura Bui, Roberta Benvenuto, Gianfranco Ferraccioli, Stefano Alivernini, Elisa Gremese
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3259 (2024)
Primary Sjögren’s disease is primarily driven by B-cell activation and is associated with a high risk of developing non-Hodgkin’s lymphoma (NHL). Over the last few decades, microRNA-155 (miR-155) has arisen as a key regulator of B-cells. Neverth
Externí odkaz:
https://doaj.org/article/3318819503d74c07bd9baaba219a55a5
Autor:
Luka de Vos, Tugce Guel, Dennis Niebel, Sandra Bald, Adrian ter Steege, Thomas Bieber, Joerg Wenzel
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Cutaneous lesions in lupus erythematosus (LE) subtypes are heterogenous. In line with the heterogeneity of the clinical presentation, the underlying lesional inflammation in LE skin samples is defined by different immune cell infiltrates. Pathophysio
Externí odkaz:
https://doaj.org/article/f82f551534254638ae6687d68107f477
Akademický článek
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Autor:
Vivien Hébert, Maud Maho-Vaillant, Marie-Laure Golinski, Marie Petit, Gaëtan Riou, Olivier Boyer, Philippe Musette, Sébastien Calbo, Pascal Joly
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The efficacy of the B-cell-depleting agent rituximab has been reported in immune diseases but relapses are frequent, suggesting the need for repeated infusions. The B-cell activating factor (BAFF) is an important factor for B cell survival, class swi
Externí odkaz:
https://doaj.org/article/5f156bfa67434cb583c5df2e5491150c
Akademický článek
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Autor:
Prasad Srikakulapu, Gorav Ailawadi, Matthew J. Johnsrude, Akshaya K. Meher, Gilbert R. Upchurch, Michael Spinosa, Melissa Lempicki, Coleen A. McNamara, Norbert Leitinger, William G. Montgomery
Publikováno v:
Am J Pathol
B cell–activating factor (BAFF), part of a tumor necrosis factor family of cytokines, was recently identified as a regulator of atherosclerosis; however, its role in aortic aneurysm has not been determined. Here, the study examined the effect of se
Publikováno v:
Current Opinion in Immunology. 71:103-110
The BAFF-receptor (BAFFR) is a member of the TNF-receptor family. It is expressed only by B cells and binds BAFF as single ligand, which activates key signaling pathways regulating essential cellular functions, including survival, protein synthesis,
Akademický článek
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Autor:
Abbas Shahi, Azin Peykari, Farzaneh Bagherpour, Bita Ansaripour, Ali Akbar Amirzargar, Samad Farashi Bonab, Marzie Esmaeili, Shima Afzali, Saeedeh Salehi, Tayebeh Soleimanian, Fatemeh Pour-Reza-Gholi
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research, Vol 2021 (2021)
Background. Kidney transplantation is the best treatment option for end stage renal disease (ESRD), but graft rejection is still a big obstacle that occurs in spite of immunosuppressive therapy. B cells are considered as the major reason for renal gr