Zobrazeno 1 - 10
of 70
pro vyhledávání: '"BABU, Gajendran"'
Autor:
Jie Wang, Chunlin Wang, Anling Hu, Kunlin Yu, Yi Kuang, Babu Gajendran, Eldad Zacksenhaus, Klarke Michael Sample, Xiao Xiao, Wuling Liu, Yaacov Ben-David
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background FLI1 is an oncogenic transcription factor that promotes diverse malignancies through mechanisms that are not fully understood. Herein, FLI1 is shown to regulate the expression of Ubiquitin Associated and SH3 Domain Containing A/B
Externí odkaz:
https://doaj.org/article/1e7a10e00166424bb547a8f8b2b0ef0d
Autor:
Krishnapriya M. Varier, Gou Dan, Xiaolong Li, Wuling Liu, Fei Jiang, Ke-Gang Linghu, Yanmei Li, Yaacov Ben-David, Nenling Zhang, Chaoda Xiao, Babu Gajendran, Xiangchun Shen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Lymphoma positions as the fifth most common cancer, in the world, reporting remarkable deaths every year. Several promising strategies to counter this disease recently include utilizing small molecules that specifically target the lymphoma cellular p
Externí odkaz:
https://doaj.org/article/50dcc2e6f69a4a239a83c482dee0e407
Autor:
Jian Gao, Jifen Hu, Fang Yu, Chunlin Wang, Danmei Sheng, Wuling Liu, Anling Hu, Kunling Yu, Xiao Xiao, Yi Kuang, Eldad Zacksenhaus, Babu Gajendran, Yaacov Ben-David
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Lovastatin, an HMG-CoA inhibitor and an effective cholesterol lowering drug, exhibits anti-neoplastic activity towards several types of cancer, although the underlying mechanism is still not fully understood. Herein, we investigat
Externí odkaz:
https://doaj.org/article/951e24cdb29a4642858a3cbf83b27f66
Autor:
Jingrui Song, Kun Yang, Babu Gajendran, Krishnapriya M. Varier, Wenxue Li, Qin Liu, Qing Rao, Yubing Hang, Xiangchun Shen, Sheng Liu, Lei Huang, Mei Xu, Yanmei Li
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 4, p 163 (2024)
Background: Glucocorticoids (GCs) are commonly used as the primary chemotherapy for lymphoid malignancies, including acute lymphoblastic leukemia (ALL). However, the development of GC resistance limits their prolonged use. Methods: In this study, we
Externí odkaz:
https://doaj.org/article/084c3e5d4764438682cdb93a3de62dec
Autor:
Lei Huang, Yanrong Zeng, Fei Li, Xiuyan Zheng, Qing Rao, Babu Gajendran, Krishnapriya M. Varier, Tong Peng, Lin Tang
Publikováno v:
Journal of Functional Foods, Vol 108, Iss , Pp 105715- (2023)
Previous reports have suggested that Idesia polycarpa Maxim. (I. polycarpa) fruits possess properties for the prevention and treatment of non-alcoholic fatty liver disease (NAFLD), owing to its lipid-lowering and anti-oxidant activities. In this stud
Externí odkaz:
https://doaj.org/article/85212b5a317a41bfb71da41c3f4600d4
Autor:
Anling Hu, Jian Gao, Krishnapriya M. Varier, Babu Gajendran, Fei Jiang, Wuling Liu, Chunlin Wang, Xiao Xiao, Yanmei Li, Eldad Zacksenhaus, Sajjad Ali, Yaacov Ben-David
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract The pyrimido-indole derivative UM171 promotes human Hematopoietic Stem Cells Expansion (HSCE), but its impact on leukemia is not known. Herein, we show in a mouse model of erythroleukemia that UM171 strongly suppresses leukemia progression.
Externí odkaz:
https://doaj.org/article/e8c6955993c6426ca9d9881906959fe9
Autor:
Krishnapriya M. Varier, Gou Dan, Wuling Liu, Guoping Wu, Chaoda Xiao, Huang Lei, Tao Ling, Yanping Jiang, Ying Chen, Yaacov Ben-David, Yanmei Li, Nenling Zhang, Babu Gajendran, Xiangchun Shen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113887- (2022)
Lymphoma is a cancer of the lymphoid cells that originated in matured B or T cells. The bioactive natural compounds can efficiently treat this disease with lesser side effects. Thus, in this study, a natural stilbene B10 (3-methoxy 5-hydroxy stilbene
Externí odkaz:
https://doaj.org/article/95d556a840b84286b9fbbfc72f973ba9
Autor:
Jianfei Qiu, Li Chen, Jue Yang, Krishnapriya M. Varier, Babu Gajendran, Yao Yao, Wuling Liu, Jingrui Song, Qing Rao, Qun Long, Chunmao Yuan, Xiaojiang Hao, Yanmei Li
Publikováno v:
Dose-Response, Vol 20 (2022)
Background Leukemia accounts for a large number of deaths, worldwide, every year. Treating this ailment is always a challenging job. Recently, oncogenic miRNA leading to apoptosis are highly promising targets of many natural products. In this study,
Externí odkaz:
https://doaj.org/article/08347f823c464c0ba97dc10c600a32a4
Autor:
YAN, Chen 1, 2, LONG, Qun 2, 3, ZHANG, Yun-Dong 1, BABU, Gajendran 2, 3, KRISHNAPRIYA, Madhu Varier 4, QIU, Jian-Fei 2, 3, SONG, Jing-Rui 2, 3, RAO, Qing 2, 3, YI, Ping 2, 3, SUN, Mao 1, 2, *, LI, Yan-Mei 2, 3, *
Publikováno v:
In Chinese Journal of Natural Medicines July 2021 19(7):528-535
Autor:
Krishnapriya M. Varier, Hemavathi Dhandapani, Wuling Liu, Jialei Song, Chunlin Wang, Anling Hu, Yaacov Ben-David, Xiangchun Shen, Yanmei Li, Babu Gajendran
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Immunotherapeutic treatments are gaining attention due to their effective anti-tumor response. Particularly, the revolution of immune checkpoint inhibitors (ICIs) produces promising outcomes for various cancer types. However, the usage of im
Externí odkaz:
https://doaj.org/article/bc84583ba62343c3b4d4534707b97c2e