Zobrazeno 1 - 10
of 176
pro vyhledávání: '"BA Parker"'
Autor:
BA Parker, Bing Cui, Suping Zhang, Thomas J. Kipps, Karen Messer, Grace Liu, Emanuela M. Ghia, Han Zhang, S Xu, Victoria Tripple, Jian Yu, George F. Widhopf, Richard Schwab
Publikováno v:
Cancer Research. 78:P1-09
Although initially responsive to chemotherapy, patients with advanced breast cancer often relapse, generally with incurable metastatic disease. This may be due to a subpopulation of tumor cells, called cancer-initiating cells, or cancer stem cells (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af74591a97c94cf81847d442ca21ff1
https://doi.org/10.1158/1538-7445.sabcs17-p1-09-07
https://doi.org/10.1158/1538-7445.sabcs17-p1-09-07
Autor:
John P. Pierce, Alwin D. R. Huitema, Sabine C. Linn, Loki Natarajan, Alan H.B. Wu, Wilbert Zwart, Xanthippi Alexi, A. H. M. de Vries Schultink, Jos H. Beijnen, Shirley W. Flatt, Lisa Madlensky, E. van Werkhoven, BA Parker
Publikováno v:
Breast Cancer Research and Treatment, 161(3), 567–574. Springer New York
Breast cancer research and treatment, vol 161, iss 3
Schultink, AHMDV; Alexi, X; van Werkhoven, E; Madlensky, L; Natarajan, L; Flatt, SW; et al.(2017). An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome. BREAST CANCER RESEARCH AND TREATMENT, 161(3), 567-574. doi: 10.1007/s10549-016-4083-6. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1bf59231
Breast Cancer Research and Treatment, 161(3), 567. Springer New York LLC
Breast cancer research and treatment, vol 161, iss 3
Schultink, AHMDV; Alexi, X; van Werkhoven, E; Madlensky, L; Natarajan, L; Flatt, SW; et al.(2017). An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome. BREAST CANCER RESEARCH AND TREATMENT, 161(3), 567-574. doi: 10.1007/s10549-016-4083-6. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1bf59231
Breast Cancer Research and Treatment, 161(3), 567. Springer New York LLC
PurposeEndoxifen concentrations have been associated with breast cancer recurrence in tamoxifen-treated patients. However, tamoxifen itself and other metabolites also show antiestrogenic anti-tumor activity. Therefore, the aim of this study was to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05120e2296c8da7622bc700bfebd4cd3
https://pubmed.ncbi.nlm.nih.gov/28005246
https://pubmed.ncbi.nlm.nih.gov/28005246
Autor:
Loki Natarajan, BA Parker, Sally A. Dominick, Ruth E. Patterson, Brinda K. Rana, Shirley W. Flatt, John P. Pierce
Publikováno v:
Cancer Research. 70:P2-09
Background: The cytokine ,Angiopoietin-2 (Ang-2), is associated with breast cancer invasion and metastasis in preclinical models and in clinicopathologic studies of breast cancer. Anti-angiogenic therapy (bevacizumab plus chemotherapy) has anti-tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac4774678f59398fac71b367b9b3cff1
https://doi.org/10.1158/0008-5472.sabcs10-p2-09-31
https://doi.org/10.1158/0008-5472.sabcs10-p2-09-31
Autor:
BA Parker, George F. Widhopf, Victoria Tripple, Suping Zhang, Jian Yu, M K Hasan, Thomas J. Kipps
Publikováno v:
Cancer Research. 78:P1-01
Background: ROR1is an evolutionarily conserved, oncoembryonic surface-antigen expressed in breast cancer. Previously, we found that ROR1 can serve as a receptor for Wnt5a, which can induce non-canonical Wnt signaling that enhances cancer-cell migrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a77aedebc60e5c3b17341ea63ed93881
https://doi.org/10.1158/1538-7445.sabcs17-p1-01-05
https://doi.org/10.1158/1538-7445.sabcs17-p1-01-05
Autor:
Richard Schwab, Teresa Helsten, Maria Schwaederle, Austin J. Parish, David Piccioni, Razelle Kurzrock, Paul T. Fanta, Kelly A. Shimabukuro, Gregory A. Daniels, BA Parker
Publikováno v:
Parish, A; Schwaederle, M; Daniels, G; Piccioni, D; Fanta, P; Schwab, R; et al.(2015). Fibroblast growth factor family aberrations in cancers: Clinical and molecular characteristics. Cell Cycle, 14(13), 2121-2128. doi: 10.1080/15384101.2015.1041691. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9mg904cd
Cell Cycle
Cell cycle (Georgetown, Tex.), vol 14, iss 13
Cell Cycle
Cell cycle (Georgetown, Tex.), vol 14, iss 13
© 2015 Taylor & Francis Group, LLC. Fibroblast growth factor ligands and receptors (FGF and FGFR) play critical roles in tumorigenesis, and several drugs have been developed to target them. We report the biologic correlates of FGF/FGFR abnormalities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b84983fb4be3d8c8e4c169cab9d5fe
http://www.escholarship.org/uc/item/9mg904cd
http://www.escholarship.org/uc/item/9mg904cd
Autor:
M Ra Crisp, BA Parker, Aaron Fleischauer, Joseph A. Truglia, Steven L. Soignet, Raymond P. Warrell, Fabio Benedetti
Publikováno v:
Leukemia. 12:1518-1521
The use of all-trans retinoic acid (RA) for remission induction markedly increases survival of patients with acute promyelocytic leukemia (APL) compared to patients treated solely with cytotoxic chemotherapy. However, clinical resistance to this agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d4f400d1109f7e4e553f96bc86ebde
https://doi.org/10.1038/sj.leu.2401150
https://doi.org/10.1038/sj.leu.2401150
Autor:
BA Parker, Minya Pu, DM Nikoloff, Fontecha, Joanne E. Mortimer, S Tchu, Ahb Wu, John P. Pierce, HJ Lawrence, Loki Natarajan, Lisa Madlensky, Grantland Hillman, Shirley W. Flatt
Publikováno v:
Clinical pharmacology and therapeutics. 89(5)
We explored whether breast cancer outcomes are associated with endoxifen and other metabolites of tamoxifen and examined potential correlates of endoxifen concentration levels in serum including cytochrome P450 2D6 (CYP2D6) metabolizer phenotype and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27db89a07a38a5604b586237bf547be5
https://pubmed.ncbi.nlm.nih.gov/21430657
https://pubmed.ncbi.nlm.nih.gov/21430657
Autor:
Razelle Kurzrock, Teresa Helsten, Haydee Ojeda-Fournier, Alice Coutinho, RB Schwab, Maria Schwaederle, BG Sarah, Brian Datnow, BA Parker
Publikováno v:
Cancer Research. 73:P4-04
Background: To realize the promise of personalized medicine, it is important to build the infrastructure to match patients to the most promising therapies using evolving genomic information to inform clinical trial and treatment recommendations. Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e0f259ada1b98166f2346597a24c169
https://doi.org/10.1158/0008-5472.sabcs13-p4-04-15
https://doi.org/10.1158/0008-5472.sabcs13-p4-04-15
Autor:
S Hao, DM Nikoloff, M Fontecha, Shirley W. Flatt, Anna E. Johnson, HJ Lawrence, BA Parker, Grantland Hillman, Lisa Madlensky, John P. Pierce, Loki Natarajan
Publikováno v:
Cancer Research. 69:6045
Abstract #6045 Background: We have previously shown that participants in the Women's Healthy Eating and Living (WHEL) study comparison group who reported hot flashes after breast cancer treatment had more favorable disease-free survival than women wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a118a71bcb68ad5117e6de0225820059
https://doi.org/10.1158/0008-5472.sabcs-6045
https://doi.org/10.1158/0008-5472.sabcs-6045
Autor:
V Sheidler, P Rubin, N Eldreth, Jill Loftiss, J Brechlin, Amv Storniolo, BA Parker, S Aranjo, G Lott, G Magrinat, Ronald A. Fleming, A Rush-Tayler, C Shaw, Barbara L. Weber
Publikováno v:
Cancer Research. 69:3121
Abstract #3121 Background: Lapatinib is a selective and highly potent dual, competitive inhibitor of erbB1 and erbB2 tyrosine kinases with clinical activity in erbB2-positive metastatic breast cancer (MBC). The combination of carboplatin, paclitaxel,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ace23c042df674af44bd3826cea4c8f
https://doi.org/10.1158/0008-5472.sabcs-3121
https://doi.org/10.1158/0008-5472.sabcs-3121