Zobrazeno 1 - 10 of 272 pro vyhledávání: '"BA Michel"'
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Akademický článek
Biologics in rheumatoid arthritis (RA) – recommendations for Swiss practice
Autor: BA Michel
Publikováno v: Swiss Medical Weekly, Vol 141, Iss 1920 (2011)
The new paradigm of therapy in rheumatoid arthritis is to aim toward early and complete remission, using a larger use of conventional DMARDs and biologic agents. The present recommendations were established through a consensus to help practitioners i
Externí odkaz: https://doaj.org/article/0bf82564039646a28a6c3b746b9a5e1a
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OP0040 Bucillamine and its metabolites induce synthesis of vegf dose dependently in systemic sclerosis fibroblasts via the nf-kb pathway
Autor: C Hagen, O Distler, U Müller-Ladner, A Carossino, RE Gay, R Nanagara, BA Michel, K Nishioka, M Matucci-Cerinic, S Gay
Publikováno v: Speaker abstracts 2001.
Background Bucillamine (BUC) is an immunomodulatory drug used in the treatment of rheumatoid arthritis with inhibitory effects on B- and T-cell functions. However, the impact of Bucillamine on metabolic pathways of fibroblasts has not been addressed.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5742e5131ebe9d58905997a740f046b6
https://doi.org/10.1136/annrheumdis-2001.297
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6
AB0206 Investigation of the inducibility of retroviruses from rheumatoid arthritis synovial fibroblasts (ra-sf) and ra-synovial fluid cells (ra-sfc)
Autor: CA Seemayer, SA Kolb, J Böni, M Neidhart, B Simmen, RE Gay, BA Michel, J Schüpbach, S Gay
Publikováno v: Speaker abstracts 2001.
Background Objectives In many investigations virus like particles (VLP) and especially type-C retroviruses could be activated from tumour cells in culture after stimulation with DNA damaging agents. Co-culture with H9 cells, a lymphatic cell line, ha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::786651cb3347e683e912cf3c32deb808
https://doi.org/10.1136/annrheumdis-2001.717
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7
THU0092 The l1 mrna in rheumatoid arthritis encodes a functional retrotransposable element
Autor: M Neidhart, J Rethage, O Distler, MT Peyer, ME Billingham, BA Michel, RE Gay, S Gay
Publikováno v: Speaker abstracts 2001.
Background L1 retrotransposons have been detected in rheumatoid arthritis (RA) at sites of joint destruction. Objectives To caracterise the L1 mRNA in RA. Methods RNA was isolated from the synovial tissue of a 35-years old woman with RA. The complete
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4013794cd74459a94a3d125251baa5f
https://doi.org/10.1136/annrheumdis-2001.969
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THU0097 The discrepancy between mrna and protein expression of the tumour-suppressor gene maspin in synovial tissue might contribute to synovial hyperplasia in rheumatoid arthritis (ra)
Autor: J Schedel, E Jeisy Walder, B Simmen, BA Michel, RE Gay, S Gay
Publikováno v: Speaker abstracts 2001.
Background RA is a chronic disease characterised by tumour-like features such as synovial hyperplasia, invasive growth of the synovium and joint destruction. Maspin is a member of the serpin family of protease inhibitors with gene sequence similariti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c126015752847633962dfe4f40359f2
https://doi.org/10.1136/annrheumdis-2001.974
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THU0109 The destructive process of rheumatoid arthritis synovial fibroblasts (ra-sf) is independent of p53
Autor: CA Seemayer, S Kuchen, M Neihart, P Kuenzler, E Neumann, M Pruschy, T Pap, WK Aicher, U Muller-Ladner, BA Michel, RE Gay, S Gay
Publikováno v: Speaker abstracts 2001.
Background Objectives The aim of this study was to investigate, whether the destructive process of synovial fibroblasts in rheumatoid arthritis is dependent on the expression of p53. Moreover, we searched for the expression of p53 in RA-SF in vitro a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8194f7e2ee23af9144f92e6bafb2a86c
https://doi.org/10.1136/annrheumdis-2001.986
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THU0104 In vivoandin vitroinvestigations of the tumour suppressor p16 in rheumatoid arthritis
Autor: P Künzler, CA Seemayer, S Kuchen, M Neidhart, M Pruschy, BA Michel, RE Gay, S Gay
Publikováno v: Speaker abstracts 2001.
Background The progression of the cell cycle is tightly controlled by cyclins and cyclin-dependent kinases. The p16Ink4a protein was identified as a specific inhibitor of cdk4. P16 inhibits the cdk4-dependent phosphorylation of the tumour suppressor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0b5e8257b6e141aefa0204b07858ca0
https://doi.org/10.1136/annrheumdis-2001.981
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