Zobrazeno 1 - 10
of 325
pro vyhledávání: '"B2M"'
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract The molecules of Major histocompatibility class I (MHC-I) load peptides and present them on the cell surface, which provided the immune system with the signal to detect and eliminate the infected or cancerous cells. In the context of cancer,
Externí odkaz:
https://doaj.org/article/c71e3ee9042744c0b8bc6457a97ff591
Autor:
Jongsuk Han, Hyeongbin Son, Daun Jung, Ki-Yeon Kim, Chaeyeon Jin, Hyeonwook Hwang, Soon-Suk Kang, Shoukhrat Mitalipov, Hee-Jung An, Yeonmi Lee, Eunju Kang
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8209 (2024)
Allogeneic natural killer (NK) cell therapy has been effective in treating cancer. Many studies have tested NK cell therapy using human pluripotent stem cells (hPSCs). However, the impacts of the origin of PSC-NK cells on competence are unclear. In t
Externí odkaz:
https://doaj.org/article/0c4a2917c4754485bffde2768a2f7fe3
Autor:
Le Li, Xing Zeng, Zheng Chao, Jing Luo, Wei Guan, Qiang Zhang, Yue Ge, Yanan Wang, Zezhong Xiong, Sheng Ma, Qiang Zhou, Junbiao Zhang, Jihua Tian, David Horne, Bertram Yuh, Zhiquan Hu, Gong‐Hong Wei, Baojun Wang, Xu Zhang, Peixiang Lan, Zhihua Wang
Publikováno v:
Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)
Abstract The Warburg effect‐related metabolic dysfunction of the tricarboxylic acid (TCA) cycle has emerged as a hallmark of various solid tumors, particularly renal cell carcinoma (RCC). RCC is characterized by high immune infiltration and thus re
Externí odkaz:
https://doaj.org/article/407d7273c52643ac8a473ac44a636bd1
Akademický článek
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Autor:
Maryam Ranjbar, Farshid Amiri, Marjan Nourigorji, Farid Torabizadeh, Mahintaj Dara, Mehdi Dianatpour
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 23, Iss 1, Pp 1-7 (2022)
Abstract Background Allogeneic stem cells are the most potent sources for replacing cell, tissue, and organ malfunctions. The clinical use of these stem cells has been limited due to the risk of immune system rejection due to the incompatibility of h
Externí odkaz:
https://doaj.org/article/39d5c4604c364e14aecbf22104a1b4de
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Bladder cancer (BC) is one of the most common malignant tumors of the urinary system, and cisplatin (CDDP) is a critical chemical drug for the treatment of BC. However, CDDP-resistance seriously limits the therapeutic efficacy of this drug f
Externí odkaz:
https://doaj.org/article/cd769f87983d42f0af7be6ae249f483b
Autor:
Justin E. Miller, Roger Castells-Graells, Mark A. Arbing, Aldo Munoz, Yi-Xiao Jiang, Charlize T. Espinoza, Brian Nguyen, Paul Moroz, Todd O. Yeates
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1122 (2023)
Beta-2 microglobulin (B2M) is an immune system protein that is found on the surface of all nucleated human cells. B2M is naturally shed from cell surfaces into the plasma, followed by renal excretion. In patients with impaired renal function, B2M wil
Externí odkaz:
https://doaj.org/article/01d9fa7c6def4492906eadd72a84cd95
Autor:
Xiao’e Fan, Manhong Xu, Xin Chen, Qianfeng Ren, Yan Fan, Ranran Wang, Jiaqi Chen, Li Cui, Zhengmin Wang, Xiaoyan Sun, Nannan Guo
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Diabetic retinopathy (DR) and diabetic kidney disease (DKD) are complications of diabetes and place serious health and economic burdens on society. However, the identification and characterization of early biomarkers for DKD, especially for nonprolif
Externí odkaz:
https://doaj.org/article/bcb94296dd554e168e7ecdfb8d374611
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Kaixiang Xu, Honghao Yu, Shuhan Chen, Yaxuan Zhang, Jianxiong Guo, Chang Yang, Deling Jiao, Tien Dat Nguyen, Heng Zhao, Jiaoxiang Wang, Taiyun Wei, Honghui Li, Baoyu Jia, Muhammad Ameen Jamal, Hong-Ye Zhao, Xingxu Huang, Hong-Jiang Wei
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Activation of human immune T-cells by swine leukocyte antigens class I (SLA-I) and class II (SLA-II) leads to xenograft destruction. Here, we generated the GGTA1, B2M, and CIITA (GBC) triple-gene-modified Diannan miniature pigs, analyzed the transcri
Externí odkaz:
https://doaj.org/article/9ca05af4819449eabec8f86f7df51267