Zobrazeno 1 - 10
of 226
pro vyhledávání: '"B2 receptors"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116489- (2024)
Maximakinin (MK), a homolog of bradykinin (BK), is extracted from skin venom of the Chinese toad Bombina maxima. Although MK has a good antihypertensive effect, its effect on myocardial cells is unclear. This study investigates the protective effect
Externí odkaz:
https://doaj.org/article/47f87a99bbf34396a1f337f3d2c98010
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Autor:
Maxime Gagnon, Martin Savard, Thi Minh Hue Tran, Laurence Vincent, Alexandre Moquin, Philippe Tremblay, Xavier Roucou, Yves Dory, Fernand Gobeil
Publikováno v:
Molecules, Vol 28, Iss 13, p 5206 (2023)
The blood–brain barrier (BBB) is a major obstacle to the development of effective therapeutics for central nervous system (CNS) disorders, including Alzheimer’s disease (AD). This has been particularly true in the case of monoclonal antibody (mAb
Externí odkaz:
https://doaj.org/article/2a33785bac604351a2642fcedd60dcaa
Autor:
Fajer Al-Shamlan, Ahmed Z. El-Hashim
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Inhaled bradykinin (BK) has been reported to both sensitize and induce cough but whether BK can centrally sensitize the cough reflex is not fully established. In this study, using a conscious guinea-pig model of cough, we investig
Externí odkaz:
https://doaj.org/article/b139d816d76549039f69b9ba0741fa98
Autor:
François Marceau, Georges E. Rivard, Julie M. Gauthier, Karen E. Binkley, Arnaud Bonnefoy, Isabelle Boccon-Gibod, Laurence Bouillet, Matthieu Picard, Ghislain Levesque, Hannah Laure Elfassy, Hélène Bachelard, Jacques Hébert, Konrad Bork
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Bradykinin (BK)-mediated angioedema (AE) states are rare acquired or hereditary conditions involving localized edema of the subcutaneous and submucosal tissues. Citrated plasma from healthy volunteers or patients with hereditary angioedema (HAE) with
Externí odkaz:
https://doaj.org/article/8214c6f93a4949ccbb088b8b53b02298
Autor:
Gobeil, Maxime Gagnon, Martin Savard, Thi Minh Hue Tran, Laurence Vincent, Alexandre Moquin, Philippe Tremblay, Xavier Roucou, Yves Dory, Fernand
Publikováno v:
Molecules; Volume 28; Issue 13; Pages: 5206
The blood–brain barrier (BBB) is a major obstacle to the development of effective therapeutics for central nervous system (CNS) disorders, including Alzheimer’s disease (AD). This has been particularly true in the case of monoclonal antibody (mAb
Akademický článek
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Publikováno v:
Pharmaceuticals, Vol 13, Iss 11, p 347 (2020)
The kallikrein–kinin system (KKS) is proposed to act as a counter regulatory system against the vasopressor hormonal systems such as the renin-angiotensin system (RAS), aldosterone, and catecholamines. Evidence exists that supports the idea that th
Externí odkaz:
https://doaj.org/article/59ebb5805f214a40b3399065d34ec868
Publikováno v:
Pharmaceuticals, Vol 13, Iss 9, p 215 (2020)
Kinins and their receptors have been implicated in a series of pathological alterations, representing attractive pharmacological targets for several diseases. The present review article aims to discuss the role of the kinin system in infectious disea
Externí odkaz:
https://doaj.org/article/d51fd9a9fdad49ecae093bad2483cc19