Zobrazeno 1 - 10
of 26
pro vyhledávání: '"B.T. Lussier"'
Publikováno v:
Scopus-Elsevier
The action of arginine vasopressin (AVP) on cytosolic free Ca2+ concentration ([Ca2+]i) was investigated in single rat pituitary corticotrophs using indo-1 microfluorimetry, in part in combination with the monitoring of membrane electrical events wit
Publikováno v:
Molecular and cellular endocrinology. 79(1-3)
The purpose of this study was to investigate the involvement of protein kinase C in growth hormone-releasing factor (GRF) action by directly measuring the effect of GRF on protein kinase C activity in purified male rat somatotrophs. Somatotrophs were
Publikováno v:
Canadian journal of physiology and pharmacology. 69(2)
The purpose of this study was to characterize the biological activity of the synthetic rat growth hormone releasing factor analogue rGRF(1–29)NH2 and to compare its action on growth hormone (GH) release to that of authentic rGRF(1–43)OH. We first
Publikováno v:
Endocrinology. 128(1)
GH-releasing factor (GRF)-stimulated GH release is dependent on a biphasic increase in free intracellular Ca2+ concentration [( Ca2+]i), resulting from an influx of Ca2+ into somatotrophs, while the inhibitory action of somatostatin (SRIF) on basal a
Publikováno v:
Endocrinology. 128(1)
This study was carried out to investigate the role of free intracellular Ca2+ ([Ca2+]i) in the action of GH-releasing factor (GRF) by determining whether GRF causes and increase in [Ca2+]i and whether this increase results from changes in Ca2+ influx
Publikováno v:
Endocrinology. 128(1)
This study was carried out to investigate the role of Ca2+ in the somatostatin (SRIF)-induced inhibition of GH release. We examined the effect of SRIF on basal and GH-releasing factor (GRF)-induced increases in Ca2+ influx and free intracellular Ca2+
Publikováno v:
Molecular and cellular endocrinology. 72(3)
We studied the role of the phosphatidylinositol system in the action of growth hormone-releasing factor (GRF). We asked whether GRF stimulates the activity of phospholipase C by determining GRF-induced changes in 32P labeling of the individual phosph
Publikováno v:
Endocrinology. 119:2047-2051
The secretion of GH is strikingly episodic. We have suggested that the timing of the episodic bursts of GH secretion is set by somatostatin (SRIF) withdrawal, whereas the magnitude of the bursts is determined by the amount of GH-releasing factor (GRF
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 66:318-320
Neuropeptide Y in concentrations from 10−8 to 10−6 M inhibits the release of α-MSH from the frog (Rana pipiens) pituitary in a reversible, sustained, and concentration-related manner. However, it does not inhibit the release of α-MSH from the r
Effect of withdrawal of somatostatin and growth hormone (GH)-releasing factor on GH release in vitro
Publikováno v:
Endocrinology. 122(5)
The secretion of GH, in vivo, is pulsatile. We have proposed that the timing of the episodic bursts of GH secretion is set by somatostatin (SRIF) withdrawal, while the magnitude of the bursts is set by the amount of GH-releasing factor (GRF) impingin