Výsledky vyhledávání - "B.R. Vijay Avin"

Akademický článek

Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma

Autor: T. Prashanth, B.R. Vijay Avin, Prabhu Thirusangu, V. Lakshmi Ranganatha, B.T. Prabhakar, J.N. Narendra Sharath Chandra, Shaukath Ara Khanum

Publikováno v: Biomedicine & Pharmacotherapy, Vol 112, Iss , Pp - (2019)

The synthesis and antiproliferative effect of a series of quinoline and thiazole containing coumarin analogs 12a-d and 13a-f respectively, on mice leukemic cells was performed. The chemical structures of newly synthesized compounds were confirmed by

Externí odkaz: https://doaj.org/article/945691e993f945feacf217e79e4908bb

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Immunomodulatory glc/man-directedDolichos lablablectin (DLL) evokes anti-tumour responsein vivoby counteracting angiogenic gene expressions

Autor: B.T. Prabhakar, V. Krishna, B.R. Vijay Avin, Prabhu Thirusangu, Siddanakoppalu N. Pramod, V. Vigneshwaran

Publikováno v: Clinical and Experimental Immunology. 189:21-35

SummaryNeovascularization and jeopardized immunity has been critically emphasized for the establishment of malignant progression. Lectins are the diverse class of carbohydrate interacting proteins, having great potential as immunopotentiating and ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d044831603d45fd528e6ea2ac65c0fe8
https://doi.org/10.1111/cei.12959

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Scutellarein antagonizes the tumorigenesis by modulating cytokine VEGF mediated neoangiogenesis and DFF-40 actuated nucleosomal degradation

Autor: H.M. Vikas, V. Vigneshwaran, Prabhu Thirusangu, H. Rakesh, B.R. Vijay Avin, B.T. Prabhakar

Publikováno v: Biochemical and Biophysical Research Communications. 484:85-92

Neoplastic cells often reside in distinctive tumor hypoxia armed with a series of adaptive responses including oxidative stress, defective apoptotic machinery and neoangiogenesis, through that further confer cell survival improvement. Plants still ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889f2d77c0d3b0f8c7613959181c07be
https://doi.org/10.1016/j.bbrc.2017.01.067

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A tumoural angiogenic gateway blocker, Benzophenone-1B represses the HIF-1α nuclear translocation and its target gene activation against neoplastic progression

Autor: V. Vigneshwaran, K. Jayashree, B.T. Prabhakar, B.R. Vijay Avin, V. Lakshmi Ranganatha, Shaukath Ara Khanum, Riaz Mahmood, Prabhu Thirusangu

Publikováno v: Biochemical Pharmacology. 125:26-40

Hypoxia is an important module in all solid tumours to promote angiogenesis, invasion and metastasis. Stabilization and subsequent nuclear localization of HIF-1α subunits result in the activation of tumour promoting target genes such as VEGF, MMPs,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed23df995a755e39df75e1a73dd631f
https://doi.org/10.1016/j.bcp.2016.11.009

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Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma

Autor: Prabhu Thirusangu, B.R. Vijay Avin, V. Lakshmi Ranganatha, J. N. Narendra Sharath Chandra, B.T. Prabhakar, Shaukath Ara Khanum, T. Prashanth

Publikováno v: Biomedicine & Pharmacotherapy, Vol 112, Iss, Pp-(2019)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3886eeea4ee898620fa8d02fc9d2346f
http://www.sciencedirect.com/science/article/pii/S0753332218381940

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Screening for the modulation of neovessel formation in non-tumorigenic and tumorigenic conditions using three different plants native to Western ghats of India

Autor: Prabhu Thirusangu, Riaz Mahmood, B.T. Prabhakar, M.V. Prashanth Kumar, C. K. Ramesh, V. Vigneshwaran, B.R. Vijay Avin

Publikováno v: Biomedicine & Aging Pathology. 4:343-348

Angiogenesis is the growth of neovessels from existing vasculature. In diseases such as cancer excessive angiogenesis occurs when diseased cells produce abnormally large amounts of angiogenic factors. A wide range of plants contains compounds with an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9a8f4be5e6a8873f1f033d95dfa5804
https://doi.org/10.1016/j.biomag.2014.07.006

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New role of lupeol in reticence of angiogenesis, the cellular parameter of neoplastic progression in tumorigenesis models through altered gene expression

Autor: C.K. Ramesh, B.T. Prabhakar, K. Jayashree, V. Vigneshwaran, Mahmood Riaz, B.R. Vijay Avin, T. Prabhu

Publikováno v: Biochemical and Biophysical Research Communications. 448:139-144

There is a major unmet medical need for effective and well tolerated treatment options for cancer. The search now seeks to identify active biomolecules with multiple targets. Lupeol, an important dietary triterpenoid known as anticarcinogen by induci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1632d46101e26742db32b7d95ef586ad
https://doi.org/10.1016/j.bbrc.2014.04.090

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Synthesis, angiopreventive activity, and in vivo tumor inhibition of novel benzophenone–benzimidazole analogs

Autor: V. Lakshmi Ranganatha, B.R. Vijay Avin, B.T. Prabhakar, Shaukath Ara Khanum, Prabhu Thirusangu, T. Prashanth

Publikováno v: Life Sciences. 93:904-911

Aim The development of anticancer drugs with specific targets is of prime importance in modern biology. This study investigates the angiopreventive and in vivo tumor inhibition activities of novel synthetic benzophenone–benzimidazole analogs. Main

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7f9717cc822d30b7fab37694ed06a4
https://doi.org/10.1016/j.lfs.2013.10.001

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