Zobrazeno 1 - 10
of 136
pro vyhledávání: '"B.L. Pool-Zobel"'
Autor:
Bas J. Blaauboer, S Kevekordes, V.A. Baker, Michael Balls, Alan R. Boobis, Angelo Carere, J Kleiner, Jean-Claude Lhuguenot, G. Eisenbrand, B.L. Pool-Zobel, Raymond Pieters
Publikováno v:
Food and Chemical Toxicology. 40:193-236
In vitro methods are common and widely used for screening and ranking chemicals, and have also been taken into account sporadically for risk assessment purposes in the case of food additives. However, the range of food-associated compounds amenable t
Autor:
U. Leucht, B.L Pool-Zobel
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 375:105-115
In order to increase the understanding of the factors responsible for causing human colon cancer, a technique was developed to detect genotoxic effects of chemicals in human colon cells. Risk factors suspected to be associated with the aetiology of h
Publikováno v:
Zeitschrift für Ernährungswissenschaft. 32:131-138
The plant flavonol quercetin and the triazine herbicides atrazine, cyanazine, and gesamprim were examined individually and in combination for the induction of genotoxic effects. The sister chromatid exchange (SCE) assay and the gene mutation assay fo
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 291:223-297
Publikováno v:
Carcinogenesis. 13:2435-2441
Toxicological mechanisms involved in organotropism of tumor induction may include cell-specific metabolic activation of the carcinogen, in vivo distribution of active metabolites and persistance of induced DNA damage. In order to elucidate which fact
Autor:
D. Biscardi, B.L. Pool-Zobel, R. De Fusco, Silvano Monarca, Rossana Pasquini, R. Rizzi, E. Piatti, P. Schmezer, P. Klein
Publikováno v:
Mutation Research Letters. 262:85-92
Dimethyl terephthalate (DMTP), the para configuration of dimethyl phthalate, is one of the basic monomers used in the synthesis of polyethylene terephthalate (PET) plastics. Human exposure to DMTP may primarily occur during the manufacture of PET fib
Publikováno v:
Cancer Letters. 55:7-11
Molecular orbital calculations with aristolochic acid I (AAI) and the model compounds 8-nitro-1-naphthoic acid (1,8NNA) and 3-nitro-2-naphthoic acid (2,3NNA) confirm a similar conformation of the nitro and carboxyl groups in these molecules. The orth
Autor:
Peter Schmezer, K. Reinhart, A. R. Tricker, P. Klein, Y. Sinrachatanant, F. Kliagasioglu, B.L. Pool-Zobel, R. Martin
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 116:475-479
A. bisporus has been reported to be carcinogenic to mice [Toth et al. (1986) Cancer Res 38:177-180] and mutagenic in Salmonella typhimurium [Sterner et al. (1982) Mutat Res 101:269-281]. The effects of different heat treatments on the mutagenicity of
Autor:
J.H.M. van Delft, Siegfried Knasmüller, Hans Verhagen, Henrik E. Poulsen, Shmuel Yannai, Okezie I. Aruoma, Lars O. Dragsted, Lynnette R. Ferguson, B.L. Pool-Zobel, Gary Williamson
Publikováno v:
Food and Chemical Toxicology, 41(5), 603-610. Elsevier Science
The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo.Verhagen H, Aruoma OI, van Delft JH, Dragsted LO, Ferguson LR, K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd7bdf0fc8cbe94e917d13efb496c03
https://cris.maastrichtuniversity.nl/en/publications/e019d3be-ae09-47a5-97f5-a4386909ffa9
https://cris.maastrichtuniversity.nl/en/publications/e019d3be-ae09-47a5-97f5-a4386909ffa9
Autor:
B.L. Pool-Zobel, R. Fautz, W. Suter, P. Schmezer, L. Müller, A.H. Seeberg, E.C. Puri, T. Hertner, W. von der Hude, G. Kaufmann, H. Madle, Herbert G. Miltenburger, R. Forster, R. Strobel, M. Baumeister, C.M.A. Hechenberger, Stephan Madle
Publikováno v:
Mutation research. 260(3)
We report the results of a collaborative study for the detection of chemical-induced DNA damage in primary cultures of rat hepatocytes. The methods include the detection of unscheduled DNA synthesis (UDS) with either autoradiography (5 laboratories)