Zobrazeno 1 - 10
of 27
pro vyhledávání: '"B.K. Ahmed Rasheed"'
Autor:
Mike West, Joseph R. Nevins, Darell D. Bigner, Holly K. Dressman, Adrian Dobra, B.K. Ahmed Rasheed, Roger E. McLendon, Edwin S. Iversen, Beatrix Jones, Christopher Hans, Jeremy N. Rich
Despite the strikingly grave prognosis for older patients with glioblastomas, significant variability in patient outcome is experienced. To explore the potential for developing improved prognostic capabilities based on the elucidation of potential bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8a8efa9b2b5a2b3abef3a0c14633c3
https://doi.org/10.1158/0008-5472.c.6494009
https://doi.org/10.1158/0008-5472.c.6494009
Supplementary Tables 1-2 from Gene Expression Profiling and Genetic Markers in Glioblastoma Survival
Autor:
Mike West, Joseph R. Nevins, Darell D. Bigner, Holly K. Dressman, Adrian Dobra, B.K. Ahmed Rasheed, Roger E. McLendon, Edwin S. Iversen, Beatrix Jones, Christopher Hans, Jeremy N. Rich
Supplementary Tables 1-2 from Gene Expression Profiling and Genetic Markers in Glioblastoma Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cfdcd5b28001cbfc856bc406d31f9e
https://doi.org/10.1158/0008-5472.22364066.v1
https://doi.org/10.1158/0008-5472.22364066.v1
Autor:
Jaclyn A. Biegel, Sueli Mieko Oba Shinjo, Xiaosong Zhang, Victor E. Velculescu, Yiping He, Stephen T. Keir, Tom Curran, Mitchel S. Berger, Daniela S. Gerhard, Nick Papadopoulos, D. Williams Parsons, Michael D. Taylor, Hai Yan, Adam C. Resnick, Peter C. Burger, Gregory J. Riggins, Giovanni Parmigiani, Darell D. Bigner, Zev A. Binder, Doug R. Smith, Henry S. Friedman, Roger E. McLendon, Scott R. VandenBerg, Jane E. Minturn, Carlos Clara, Alexander R. Judkins, Simina M. Boca, Siân Jones, George I. Jallo, Rachel Karchin, Kenneth W. Kinzler, Chetan Bettegowda, Gary L. Gallia, Meng Li, Yuri Nikolsky, Peter C. Phillips, James Hartigan, Rebecca J. Leary, Phillip B. Storm, Hannah Carter, Suely Kazue Nagahashi Marie, Josue Samayoa, Paul A. Northcott, Bert Vogelstein, B.K. Ahmed Rasheed, Jimmy Lin, Daniel W. Fults
Publikováno v:
Science. 331:435-439
Medulloblastoma (MB) is the most common malignant brain tumor of children. To identify the genetic alterations in this tumor type, we searched for copy number alterations using high-density microarrays and sequenced all known protein-coding genes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eecda1f1d0b7cf8eab59dc6fcb1ee71
https://doi.org/10.1126/science.1198056
https://doi.org/10.1126/science.1198056
Autor:
David A. Reardon, Roger E. McLendon, Catherine Wheeler, Mark W. Kieran, B.K. Ahmed Rasheed, Darell D. Bigner, Sith Sathornsumetee, Anderson J. Ryan, Jeremy N. Rich, Ling Wang, Stephen T. Keir, Isaiah Dimery, Henry S. Friedman, Michael W. Graner, Arja Kaipainen, Andrea Laforme
Publikováno v:
Clinical Cancer Research. 11:8145-8157
Purpose: Primary central nervous system (CNS) tumors represent a diverse group of tumor types with heterogeneous molecular mechanisms that underlie their formation and maintenance. CNS tumors depend on angiogenesis and often display increased activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1932cc238bc41cb85f5f1bab641e17
https://doi.org/10.1158/1078-0432.ccr-05-0319
https://doi.org/10.1158/1078-0432.ccr-05-0319
Autor:
Roger E. McLendon, David Reardon, James E. Herndon, Rodney N. Wiltshire, Allan H. Friedman, B S Bryan West, Darell D. Bigner, B.K. Ahmed Rasheed, Jennifer Quinn, Henry S. Friedman
Publikováno v:
Cancer. 104:1693-1699
BACKGROUND Allelic losses of 1p and 19q arms correlate with the oligodendroglial phenotype as well as with sensitivity to radiotherapy and chemotherapy. Furthermore, the DNA repair gene, methylguanine methyltransferase (MGMT), is diminished in 80% of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea9f8ee1e7c045295300da8624e31bb
https://doi.org/10.1002/cncr.21362
https://doi.org/10.1002/cncr.21362
Autor:
Chris Hans, Darell D. Bigner, Holly K. Dressman, Mike West, Joseph R. Nevins, B.K. Ahmed Rasheed, Edwin S. Iversen, Jeremy N. Rich, Adrian Dobra, Roger E. McLendon, Beatrix Jones
Publikováno v:
Cancer Research. 65:4051-4058
Despite the strikingly grave prognosis for older patients with glioblastomas, significant variability in patient outcome is experienced. To explore the potential for developing improved prognostic capabilities based on the elucidation of potential bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a574f9c5ac27651f4cbd2850346d81cf
https://doi.org/10.1158/0008-5472.can-04-3936
https://doi.org/10.1158/0008-5472.can-04-3936
Autor:
Carol J. Wikstrand, Henry S. Friedman, Terry S. Peery, Jennifer A. Quinn, Sandra Tourt-Uhlig, Janet Dancey, Lauren B. Van Duyn, Roger E. McLendon, James C. Kao, Allan H. Friedman, James J. Vredenburgh, Kara Penne, Darell D. Bigner, James E. Herndon, Timothy T. Stenzel, Jeremy N. Rich, David A. Reardon, John H. Sampson, Jeannette M. Dowell, B.K. Ahmed Rasheed
Publikováno v:
Journal of Clinical Oncology. 22:133-142
Purpose To evaluate the efficacy and tolerability of gefitinib (ZD1839, Iressa; AstraZeneca, Wilmington, DE), a novel epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. Patients and Methods This was a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad9c7c858a54335e8e1e9c338aafe0d
https://doi.org/10.1200/jco.2004.08.110
https://doi.org/10.1200/jco.2004.08.110
Autor:
B.K. Ahmed Rasheed, Henry S. Friedman, Allan H. Friedman, Rodney N. Wiltshire, Sandra H. Bigner
Publikováno v:
Neuro-Oncology. 2:164-173
Cytogenetic and molecular genetic studies of glioblastoma multiforme (GBM) have shown that the most frequent alterations are gains of chromosome 7, losses of 9p loci and chromosome 10, and gene amplie cation, primarily of the epidermal growth factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c61190b400259abe069704bdf058ae
https://doi.org/10.1093/neuonc/2.3.164
https://doi.org/10.1093/neuonc/2.3.164
Publikováno v:
Neuro-Oncology. 1:52-60
Morphologic criteria for diagnosing oligodendrogliomas and for classifying them as well-differentiated (World Health Organization grade II) and anaplastic (World Health Organization grade III) are well recognized. Nevertheless, applying these guideli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b92399ccc74519f4699d488b583247c
https://doi.org/10.1093/neuonc/1.1.52
https://doi.org/10.1093/neuonc/1.1.52
Autor:
Sian Jones, Allan H. Friedman, Roger E. McLendon, Henry S. Friedman, Eric S. Lipp, Hai Yan, Patrick J. Killela, Darell D. Bigner, Zachary J. Reitman, Christopher J. Pirozzi, Yiping He, B.K. Ahmed Rasheed
Publikováno v:
Oncotarget
Anaplastic astrocytoma WHO grade III (A3) is a lethal brain tumor that often occurs in middle aged patients. Clinically, it is challenging to distinguish A3 from glioblastoma multiforme (GBM) WHO grade IV. To reveal the genetic landscape of this tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f376f55055f0e4a231b295d493d480f
https://pubmed.ncbi.nlm.nih.gov/24140581
https://pubmed.ncbi.nlm.nih.gov/24140581