Zobrazeno 1 - 10
of 22
pro vyhledávání: '"B.J. Bewsey"'
Publikováno v:
Mutation Research/Genetic Toxicology. 341:185-192
Bacterial test systems have been used extensively to identify the mutagenic potential of new compounds. In particular, the Ames test has gained worldwide acceptance and is required by many regulatory agencies to support product registration. The grad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278d23216d73b5a6b385760a83804699
https://doi.org/10.1016/0165-1218(95)90008-x
https://doi.org/10.1016/0165-1218(95)90008-x
Autor:
Delinda E.F. Kindig, Steven B. Neal, M.A. Rexroat, E. R. Adams, Gregory S. Probst, M.L. Garriott, B.J. Bewsey, John L. Emmerson, T.J. Oberly
Publikováno v:
Mutation Research/Genetic Toxicology. 260:187-193
This paper reports the results of studies conducted within the Lily Research Laboratories and discusses additional studies with trifluralin that have been reported in the literature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc61b802beff303c96567db7656c7f6
https://doi.org/10.1016/0165-1218(91)90007-9
https://doi.org/10.1016/0165-1218(91)90007-9
Publikováno v:
Cell biology and toxicology. 9(3)
The mouse lymphoma assay (MLA) and Chinese hamster ovary (CHO) cell assay are sensitive indicators of mutagenicity. The CHO assay has been modified technically to permit treatment in suspension and soft agar cloning comparable to the MLA. This method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3549a26c1334c931d801b85af2c05c2
https://pubmed.ncbi.nlm.nih.gov/8299003
https://pubmed.ncbi.nlm.nih.gov/8299003
Publikováno v:
Mutation research. 241(2)
The hair-dye ingredients, HC Blue No. 1 (HCB1) and HC Blue No. 2 (HCB2), were tested for the induction of bacterial mutation using Salmonella typhimurium strains TA1535, TA1537, TA98 and TA100; and Escherichia coli strains WP2uvrA-. In addition, both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9248427ce7deeec7870a83621d6d5dd
https://pubmed.ncbi.nlm.nih.gov/2189067
https://pubmed.ncbi.nlm.nih.gov/2189067
Autor:
Christina Z. Thompson, Steven B. Neal, Leo E. Hill, T.J. Oberly, J. K. Epp, Gregory S. Probst, B.J. Bewsey
Publikováno v:
Annals of the New York Academy of Sciences. 407:334-350
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a07737d9bd5cd15e355af36c804520f
https://doi.org/10.1111/j.1749-6632.1983.tb47839.x
https://doi.org/10.1111/j.1749-6632.1983.tb47839.x
Publikováno v:
Journal of Toxicology and Environmental Health. 6:333-349
DNA damage induced by five ultimate carcinogens and five procarcinogens was evaluated by three methods: (1) DNA strand breaks in Crandall feline kidney (CRFK) cells measured by alkaline sucrose gradient centrifugation; (2) unscheduled DNA synthesis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295ab2bf29592a31dd1349a583a3bb0a
https://doi.org/10.1080/15287398009529855
https://doi.org/10.1080/15287398009529855
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 125:291-306
The L5178YTK+/- mouse lymphoma assay (MLA) has been utilized in several laboratories as a short-term test for chemical-induced forward mutation in cultured mammalian cells. In order to evaluate several technical modifications to the MLA, 42 chemicals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92d80229425959a4fbfbcbe1ce4b5b2
https://doi.org/10.1016/0027-5107(84)90079-4
https://doi.org/10.1016/0027-5107(84)90079-4
Publikováno v:
Mutation research. 161(2)
L5178Y/TK+/- cells were treated with 3-methylcholanthrene (3MC) in order to obtain thymidine-kinase-deficient mutants (TK-/-) which were resistant to trifluorothymidine (TFTr). Clones of TK-/- cells were harvested from soft agar and adapted to growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0be4b1fe9105ffe97059ed5ae3db209
https://pubmed.ncbi.nlm.nih.gov/3088439
https://pubmed.ncbi.nlm.nih.gov/3088439
Autor:
Leo E. Hill, M.A. Rexroat, Christina Z. Thompson, T.J. Oberly, Steven B. Neal, A.M. Bendele, William W. Carlton, B.J. Bewsey, Gregory S. Probst
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 23(10)
Ochratoxin A (OA), a nephrotoxic mycotoxin, was evaluated for genotoxic potential in a battery of in vitro and in vivo assays. OA was not mutagenic to Salmonella typhimurium, either with or without metabolic activation, in the plate incorporation (Am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c76a83326ca83ba8b214ffc333a77b
https://pubmed.ncbi.nlm.nih.gov/3905543
https://pubmed.ncbi.nlm.nih.gov/3905543
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