Zobrazeno 1 - 10
of 23
pro vyhledávání: '"B.J Majer"'
Autor:
Siegfried Knasmüller, Asima Chakraborty, B.J Majer, Armen Nersesyan, Michael Kundi, Franziska Ferk, Tamara Grummt, Heinz-Günter Wunderlich, Wolfram Parzefall
Publikováno v:
Environmental and Molecular Mutagenesis. 47:95-106
2-Amino-4,6-dinitrobenzoic acid (2-A-4,6-DNBA), 4-amino-2,6-dinitrobenzoic acid (4-A-2,6-DNBA), 2,4,6-trinitrobenzoic acid (2,4,6-TNBA), 2-amino-4, 6-dinitrobenzylalcohol (2-A-4,6-DNBAlc), 4-amino-2,6-dinitrobenzylalcohol (4-A-2,6-DNBAlc), 2,4-dinitr
Publikováno v:
Acta hydrochimica et hydrobiologica. 33:45-55
The present article describes the use of plant bioassays for the detection of genotoxins in the aquatic environment and gives an overview of test methods, their detection spectrum for environmental mutagens and carcinogens and their limitations and p
Autor:
Kristal de Wit, B.J Majer, Volker Mersch-Sundermann, Brenda Laky, Siegfried Knasmüller, Firouz Darroudi
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 551:153-166
Aim of the study was to investigate the usefulness of two human derived hepatoma cell lines (HepG2 and Hep3B) for the detection of dietary and lifestyle related DNA-reactive carcinogens. Comparisons of the sensitivity of HepG2 cells of different orig
Autor:
Sebastian Kevekordes, Christine Hoelzl, Volker Mersch-Sundermann, B.J Majer, Siegfried Knasmüller, Wolfgang W. Huber, Firouz Darroudi, Julia Bichler
Publikováno v:
Toxicology. 198:315-328
This article gives an overview of the results of genotoxicity tests, which have been conducted within the last 5 years with the human liver cell line HepG2. It is an update of an earlier review from 1998 (by Knasmüller et al.). In addition, a number
Autor:
Siegfried Knasmüller, W. Pfau, Firouz Darroudi, Y Sasaki, Hansruedi Glatt, B.J Majer, Fekadu Kassie, Walter Meinl
Publikováno v:
Journal of Chromatography B. 802:167-173
Aim of the present study was the investigation of the genotoxicity of amino-alpha-carboline (AalphaC) in human derived cells and of its organ-specific effects in laboratory rodents. This heterocyclic amine (HA) is contained in fried meat and fish in
Autor:
M Gann, Maria Uhl, Firouz Darroudi, Siegfried Knasmüller, B.J Majer, Veronika Ehrlich, Hans Steinkellner, M Eisenbauer
Publikováno v:
Food and Chemical Toxicology. 40:1085-1090
Ochratoxin A (OTA) is a widespread mycotoxin that occurs in many commodities from grains to coffee beans all over the world. Evidence is accumulating that OTA may cause cancer in humans. The compound was tested in micronucleus (MN) and single-cell ge
Publikováno v:
Food and Chemical Toxicology. 40:1051-1062
It is well documented that dietary factors play a crucial role in the aetiology of human cancer and strong efforts have been made to identify protective (antimutagenic and anticarcinogenic) substances in foods. Although numerous studies have been pub
Autor:
Siegfried Knasmüller, Rainer Wennrich, B.J Majer, Michael Kundi, Albrecht Paschke, Ellen Kandeler, Dagmar Tscherko
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 515:111-124
The aim of this study was to investigate correlation between genotoxic effects and changes of microbial parameters caused by metal contamination in soils. In total, 20 soils from nine locations were examined; metal contents and physicochemical soil p
Autor:
Siegfried Knasmüller, E. Hofer, B.J. Majer, Christophe Cavin, Walter Meinl, Hansruedi Glatt, Evelyne F. Lhoste, Maria Uhl
Publikováno v:
Food and Chemical Toxicology
Food and Chemical Toxicology, Elsevier, 2005, 43 (3), pp.433-441. ⟨10.1016/j.fct.2004.11.009⟩
Food and Chemical Toxicology, Elsevier, 2005, 43 (3), pp.433-441. ⟨10.1016/j.fct.2004.11.009⟩
Aim of the present experiments was to study the genotoxic effects of coffee diterpenoids, namely cafestol palmitate and a mix of cafestol and kahweol (C+K) in human derived hepatoma (HepG2) cells. Furthermore, we investigated the potential protective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0309474bb3e1af8009a08ab5897f02
https://hal.inrae.fr/hal-02681126
https://hal.inrae.fr/hal-02681126
Autor:
B.J Majer, Wolfgang W. Huber, Firouz Darroudi, Christophe Cavin, Veronika Ehrlich, Asima Chakraborty, Siegfried Knasmüller
Publikováno v:
Nutrition and cancer. 50(2)
To elucidate the effects of three structurally related mycotoxins, namely, ochratoxin A (OTA), ochratoxin B (OTB), and citrinin (CIT), on human health, we investigated their acute toxic, mitogenic, and genotoxic effects in the human-derived liver cel