Zobrazeno 1 - 10
of 251
pro vyhledávání: '"B.H. Anderton"'
Autor:
Peter M. Bayley, C. H. Reynolds, U. Wagner, G. M. Gibb, B.H. Anderton, André Vandecandelaere, M. A. Utton, Christopher C.J. Miller
Publikováno v:
Biochemical Journal. 323:741-747
To study the effects of phosphorylation by glycogen synthase kinase-3β (GSK-3β) on the ability of the microtubule-associated protein tau to promote microtubule self-assembly, tau isoform 1 (foetal tau) and three mutant forms of this tau isoform wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d705ff50e4d1ede316fc83ed965ad929
https://doi.org/10.1042/bj3230741
https://doi.org/10.1042/bj3230741
Autor:
Anthony J. Baines, scott Nicol, C.L. Hartley, B.H. Anderton, K.M. Chan, S.M. Thomas, H.B. Johnston
Publikováno v:
Toxicology in Vitro. 10:539-550
A simple method for differentiating human-derived SH-SY5Y neuroblastoma cells to provide a stable, mature, neuronal morphology is described. SH-SY5Y cells can be induced to differentiate terminally with retinoic acid in medium with low levels of seru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec092d6885bec14bf38ff4301b5bdfb
https://doi.org/10.1016/s0887-2333(96)00041-0
https://doi.org/10.1016/s0887-2333(96)00041-0
Autor:
B.H. Anderton, J.-P. Brion, A-M. Couck, D.R. Davis, J.-M. Gallo, D.P. Hanger, K. Ladhani, D.A. Latimer, C. Lewis, S. Lovestone, B. Marquardt, C.C.J. Miller, S.F.C. Mulot, C.H. Reynolds, T. Rupniak, C.J. Smith, S. Stabel, J. Woodgett
Publikováno v:
Scopus-Elsevier
Two cellular systems have been used to investigate the modulation of tau hyperphosphorylation. In the first system, the effects of the excitatory amino acid glutamate, the microtubule destabilising agent colchicine, and beta 25-35-amyloid peptide on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555b18e910d243973739971a7c9f3a45
https://doi.org/10.1016/0197-4580(94)00160-3
https://doi.org/10.1016/0197-4580(94)00160-3
Publikováno v:
Neuroscience Letters. 182:159-162
The neurotoxin β-N- oxalylamino- l -alanine (BOAA), found in Lathyrus sativus seeds, is thought to be the causative agent of neurolathyrism. We have investigated the neuroprotective effects of free radical scavengers on BOAA-induced toxicity followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90eabb862eae7614e7fe5115728c1b7d
https://doi.org/10.1016/0304-3940(94)90787-0
https://doi.org/10.1016/0304-3940(94)90787-0
Publikováno v:
Brain Research. 627:55-62
The neurotoxin beta-N-oxalylamino-L-alanine (BOAA), found in Lathyrus sativus seeds, is thought to be the causative agent of neurolathyrism. We have investigated the in vivo mechanism of action of BOAA by focal injection (1 microliter) in the dorsal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1946abc0e6647f669bdcc846d56111a3
https://doi.org/10.1016/0006-8993(93)90748-c
https://doi.org/10.1016/0006-8993(93)90748-c
Publikováno v:
Scopus-Elsevier
The neuronal microtubule-associated protein, tau, is expressed as a set of isoforms containing either three or four tandemly repeated 31-amino-acid motifs in the C-terminal half of the molecule that can bind to microtubules. Three-repeat forms are th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6594651421237f5b70c279dc37e4444
https://doi.org/10.1042/bj2860399
https://doi.org/10.1042/bj2860399
Autor:
B.H. Anderton, S.M. Thomas
Publikováno v:
Toxicology in Vitro. 5:173-180
Cultured neuroblastoma cells were used to study the toxic effects of the two neurotoxins methylphenylpyridinium (MPP(+)) and kainic acid. Degradation of cellular proteins (as an indicator of toxin-induced protein damage) and cell death were measured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf41df36607f25a6c94570f82d628df6
https://doi.org/10.1016/0887-2333(91)90039-g
https://doi.org/10.1016/0887-2333(91)90039-g
Autor:
R Dayanandan, Simon Lovestone, J. M. Spink, Orestes Vicente Forlenza, B.H. Anderton, O. F. Olesen
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 107(10)
Muscarinic agonists alter the metabolism of amyloid precursor protein, leading to an increase in alpha-secretase cleavage and a decreased production of amyloidogenic peptides; suggesting that these compounds might modify the Alzheimer's disease proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861bc267be242cd9ff19b8e7ee6b52bf
https://pubmed.ncbi.nlm.nih.gov/11129110
https://pubmed.ncbi.nlm.nih.gov/11129110
Autor:
V.E.R. Anderson, C. C. Nolan, M. P. Seville, Iradj Hajimohammadreza, J. B. Cavanagh, Peter Leigh, B.H. Anderton
Publikováno v:
Brain research. 640(1-2)
Infusion of the serine and thiol protease inhibitor, leupeptin, is known to cause a reduction of fast axoplasmic transport, and accumulation of lysosomal dense bodies in neuronal perikarya. We have found these dense bodies in hippocampal and cerebell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d525d6dc5d4c308f2949fe5e01d873cf
https://pubmed.ncbi.nlm.nih.gov/8004453
https://pubmed.ncbi.nlm.nih.gov/8004453
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