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pro vyhledávání: '"B.G. Snider"'
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Publikováno v:
International Journal of Pharmaceutics. 66:63-70
The major degradation products occurring in pH 2–3.75 solutions of a 21-aminosteroid (tirilazad) are described. Degradation products were identified using two methods. In the first method, molecular ion information obtained from LC/MS of degraded s
Autor:
B.G. Snider
Publikováno v:
Journal of Chromatography A. 351:548-553
Publikováno v:
Journal of Chromatography A. 367:254-259
Piriprost potassium [potassium salt of 6,9-deepoxy-6,9(phenylimino)-d 6*8prostaglandin I1 (Fig. 1) is a selective inhibitor of leukotriene synthesis and is currently the subject of clinical studieslp4. An analytical method was needed to analyze bulk
Publikováno v:
Journal of Chromatography A. 281:151-157
A normal-phase high-performance liquid chromatography system was developed to separate the prostaglandin, 15( S )-15-methyl PGF 2α methyl ester, from its 5,6- trans isomer and 15( R )-epimer. Several other related prostaglandins are resolved from th
Autor:
B.G. Snider, D.M. McDaniel
Publikováno v:
Journal of Chromatography A. 404:123-132
The enantiomers of three α-arylacetic acids (ibuprofen, flurbiprofen, and α-methoxyphenylacetic acid) were resolved as amide derivatives on high-performance liquid chromatographic chiral statinary phases consisting of covalently bound R)-N-(3,5-din
Autor:
B.G Snider, Ronald A. Hill
Publikováno v:
International Journal of Pharmaceutics. 36:175-183
An automated sampling apparatus for drug release testing is described that is chemically inert and can filter particulates larger than 0.2 μm. Samples are pushed through filters with inert piston pumps capable of delivering up to 100 psi, so that sm
Publikováno v:
Journal of Pharmaceutical Sciences. 70:1347-1349
Methods for the determination of flurbiprofen and ibuprofen in dog serum were developed using high-performance liquid chromatography and automated serum extraction. Sample extraction was automated by use of cartridges packed with a styrene-divinylben
Publikováno v:
Journal of chromatography. 321(1)
An high-performance liquid chromatography method was developed that separates (5Z)-9 beta-methyl-6 alpha-carbaprostaglandin I2 (9 beta-methylcarbacyclin; ciprostene) from several closely related isomers: (i) a double bond isomer at C-5, (ii) an epime