Zobrazeno 1 - 10
of 26
pro vyhledávání: '"B.G. Boyes"'
Publikováno v:
Mutation Research/Genetic Toxicology. 280:17-27
tert.-Butylhydroquinone (TBHQ) has been reported to be genotoxic in some short-term assays but non-genotoxic in others. We have examined cytotoxicity and genotoxicity of TBHQ, a principal metabolite of the phenolic antioxidant 2(3)-tert.-butyl-4-hydr
Publikováno v:
Mutation Research/Genetic Toxicology. 259:111-121
1-Nitronaphthalene (1-NN) has been identified in the U.S. National Toxicology Program as a non-carcinogen showing some evidence of in vitro genotoxicity. We tested this compound in Chinese hamster V79 cells at 20-80 micrograms/ml with two endpoints:
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 234:81-89
In contrast to the “validation” of short-term in vitro genotoxicity assays by concordance with the rodent cancer bioassay, the present report describes the multiple replication of 4 short-term tests with V79 cells (micronucleus assay, MN; sister-
Publikováno v:
Mutation research. 241(4)
Health concerns have arisen due to the formation of N-nitrosodibenzylamine (NDBzA; CAS No. 5336-53-8) in pork processed in a new type of rubber netting. In view of the potent carcinogenicity of related nitrosamines (e.g. N-nitroso-n-dibutylamine and
Publikováno v:
Mutation research. 244(2)
When 7,12-dimethylbenz[a]anthracene (DMBA) and aflatoxin B1 (AFB1) were activated by hepatocytes from Fischer 344 rats fed a diet containing 2% butylated hydroxyanisole (BHA), frequencies of mutation to 6-thioguanine resistance (TGR) at the HGPRTase
Autor:
J.J. Koval, B.G. Boyes
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 108:239-249
In order to determine whether the micronucleus test could be used as a rapid assay for mutagenic interactions, we studied the effect of 50–800 R of γ radiation in combination with 10−6–10−3 M caffeine in cultured human lymphocytes, with two
Autor:
D.L. Arnold, B.G. Boyes
Publikováno v:
Mutation research. 221(2)
Article de synthese sur les donnees chimiques et metaboliques concernant la saccharine, test in vitro utilisant des microorganismes, des mammiferes, et tests in vivo a court terme
Publikováno v:
Mutation research. 205(1-4)
V79 Chinese hamster lung cells were used to evaluate in vitro the cytotoxicity and genotoxicity of erythrosine (2', 4', 5', 7'-tetraiodofluorescein disodium salt; FD and C Red No. 3), a color additive used widely in foods, drugs and cosmetics. Erythr
Autor:
C.G. Rogers, B.G. Boyes
Publikováno v:
Mutation research. 226(3)
Domoic acid, a recognized neurotoxin derived from contaminated samples of the blue mussel (Mytilus edulis L.), was analyzed for mutagenicity at 2 loci and for 2 cytogenetic parameters in a hepatocyte-mediated assay with V79 Chinese hamster lung fibro
Autor:
J.J. Koval, B.G. Boyes
Publikováno v:
International journal of radiation biology and related studies in physics, chemistry, and medicine. 47(3)