Zobrazeno 1 - 10 of 102 pro vyhledávání: '"B. van het Hof"'
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Akademický článek
Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2
Autor: D. Vacondio, H. Nogueira Pinto, L. Coenen, I. A. Mulder, R. Fontijn, B. van het Hof, W. K. Fung, A. Jongejan, G. Kooij, N. Zelcer, A. J. Rozemuller, H. E. de Vries, N. M. de Wit
Publikováno v: Cell Death and Disease, Vol 14, Iss 11, Pp 1-14 (2023)
Abstract In Alzheimer’s disease (AD) more than 50% of the patients are affected by capillary cerebral amyloid-angiopathy (capCAA), which is characterized by localized hypoxia, neuro-inflammation and loss of blood-brain barrier (BBB) function. Moreo
Externí odkaz: https://doaj.org/article/32d8b02e24794774aae5c3921f638265
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2
Akademický článek
Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis
Autor: Wissam Beaino, Bieneke Janssen, Gijs Kooij, Susanne M. A. van der Pol, B. van Het Hof, Jack van Horssen, Albert D. Windhorst, Helga E. de Vries
Publikováno v: Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-16 (2017)
Abstract Background Microglia are major players in the pathogenesis of multiple sclerosis (MS) and may play a dual role in disease progression. The activation status of microglia in vivo is highly dynamic and occurs as a continuum, with the pro-infla
Externí odkaz: https://doaj.org/article/486a905d11334969992e19ca79e96e34
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3
Akademický článek
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4
Increased matrix metalloproteinases expression in tuberous sclerosis complex: modulation by microRNA 146a and 147b in vitro
Autor: Eleonora Aronica, Jasper J. Anink, Laura Wierts, E.A. van Vliet, P.C. van Rijen, H.E. de Vries, W. W. Kamphuis, J. van Scheppingen, Wim G.M. Spliet, Diede W. M. Broekaart, B. van het Hof, Floor E. Jansen
Publikováno v: Neuropathology and Applied Neurobiology
Neuropathology and Applied Neurobiology, 46(2), 142-159. Wiley-Blackwell
Broekaart, D W M, van Scheppingen, J, Anink, J J, Wierts, L, van het Hof, B, Jansen, F E, Spliet, W G, van Rijen, P C, Kamphuis, W W, de Vries, H E, Aronica, E & van Vliet, E A 2020, ' Increased matrix metalloproteinases expression in tuberous sclerosis complex: modulation by microRNA 146a and 147b in vitro ', Neuropathology and Applied Neurobiology, vol. 46, no. 2, pp. 142-159 . https://doi.org/10.1111/nan.12572
Neuropathology and applied neurobiology, 46(2), 142-159. Wiley-Blackwell
AIM Matrix metalloproteinases (MMPs) and their endogenous tissue inhibitors (TIMPs) control proteolysis within the extracellular matrix (ECM) of the brain. Dysfunction of this enzymatic system due to brain inflammation can disrupt the blood-brain bar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4016a114c367b0de118ad7740fe0df3a
https://pubmed.ncbi.nlm.nih.gov/31183875
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5
Akademický článek
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6
Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis
Autor: Susanne M. A. van der Pol, Jack van Horssen, Albert D. Windhorst, Gijs Kooij, B. van het Hof, Bieneke Janssen, Helga E. de Vries, Wissam Beaino
Publikováno v: Journal of Neuroinflammation, 14(1). BioMed Central
Journal of Neuroinflammation
Beaino, W, Janssen, B, Kooij, G, van der Pol, S M A, van Het Hof, B, van Horssen, J, Windhorst, A D & de Vries, H E 2017, ' Purinergic receptors P2Y12R and P2X7R : potential targets for PET imaging of microglia phenotypes in multiple sclerosis ', Journal of Neuroinflammation, vol. 14, no. 1, pp. 259 . https://doi.org/10.1186/s12974-017-1034-z
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-16 (2017)
Background Microglia are major players in the pathogenesis of multiple sclerosis (MS) and may play a dual role in disease progression. The activation status of microglia in vivo is highly dynamic and occurs as a continuum, with the pro-inflammatory a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f995f5ec4ee2944d007376fd734aacc6
https://research.vumc.nl/en/publications/7e05e72c-37fe-4152-beb3-36e4f032a254
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7
Specific glycosylation of alpha(1)-acid glycoprotein characterises patients with familial Mediterranean fever and obligatory carriers of MEFV
Autor: D.C.W. Poland, J.P.H. Drenth, W. W. van Dijk, B. Van het Hof, E. Rabinovitz, A. Livneh, J. Bijzet
Publikováno v: Annals of the Rheumatic Diseases, 60, 777--80
Annals of the Rheumatic Diseases, 60(8), 777-780. BMJ PUBLISHING GROUP
Annals of the Rheumatic Diseases, 60, 8, pp. 777--80
Item does not contain fulltext BACKGROUND: Familial Mediterranean fever (FMF) is a periodic febrile disorder, characterised by fever and serositis. The acute phase response during attacks of FMF results from the release of cytokines, which in turn in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b93022207ebdc3afae36c4006eec6d
https://hdl.handle.net/2066/185779
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8
[Untitled]
Autor: Carolien A. M. Koeleman, B. van het Hof, Dennis C. W. Poland, W. van Dijk, Casper G. Schalkwijk, C.D.A. Stehouwer
Publikováno v: Glycoconjugate Journal. 18:261-268
Diabetic mellitus is attended by the development of endothelial dysfunction which is suggested to be accompanied with a chronic low-degree of inflammation. During a chronic hepatic inflammatory response, specific changes in glycosylation of the acute
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c8542952a5a19150bb292609ceb3672
https://doi.org/10.1023/a:1012412908983
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9
[Untitled]
Autor: Ellen C. Havenaar, Abass Alavi, W. van Dijk, John S. Axford, E. C. M. Brinkman-Van Der Linden, Tim D. Spector, E. C. R. Van Ommen, Andrzej Mackiewicz, B. van het Hof
Publikováno v: Glycoconjugate Journal. 15:723-729
Patients suffering from rheumatoid arthritis (RA) may experience a temporary reduction of disease symptoms during pregnancy. As indicated by the occurrence of RA-disease symptoms during pregnancy, three categories of patients were defined, namely, re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::506a82b63d34da6af64e45bfb12a8819
https://doi.org/10.1023/a:1006944700325
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10
Retinoic acid induces blood-brain barrier development
Autor: Dirk Geerts, D. Wooldrik, Eleonora Aronica, B. van het Hof, Mark R. Mizee, Joost A. R. Drexhage, Arie Reijerkerk, Marianna Bugiani, H.E. de Vries, Alexandre Prat, Kim Lakeman, Reina E. Mebius
Publikováno v: Journal of Neuroscience, 33(4), 1660-1671. Society for Neuroscience
Journal of Neuroscience, 33(4), 1660-71. Society for Neuroscience
Journal of neuroscience, 33(4), 1660-1671. Society for Neuroscience
Mizee, M R, Wooldrik, D, Lakeman, K A M, van het Hof, B, Drexhage, J A R, Geerts, D, Bugiani, M, Aronica, E, Mebius, R E, Prat, A, de Vries, H E & Reijerkerk, A 2013, ' Retinoic acid induces blood-brain barrier development ', Journal of Neuroscience, vol. 33, no. 4, pp. 1660-1671 . https://doi.org/10.1523/JNEUROSCI.1338-12.2013
The blood–brain barrier (BBB) is crucial in the maintenance of a controlled environment within the brain to safeguard optimal neuronal function. The endothelial cells (ECs) of the BBB possess specific properties that restrict the entry of cells and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0da2c6fd9891e63befc69ad48b26a1f
https://research.vumc.nl/en/publications/ed7c320a-6f97-4870-8dd8-46aea725e818
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