The Influence of Human N-Acetyltransferase Genotype on the Early Bactericidal Activity of Isoniazid

Autor: Amour Venter, Cedric J. Werely, H. I. Seifart, Peter R. Donald, D. P. Parkin, B. W. Van de Wal, P. D. van Helden, F. A. Sirgel, J. S. Maritz

Publikováno v: Clinical Infectious Diseases. 39:1425-1430

The elimination of isoniazid is subject to the influence of the N-acetyltransferase 2 (NAT2) genotype, and individuals may be homozygotic slow, heterozygotic fast, or homozygotic fast acetylators of isoniazid. The early bactericidal activity (EBA) of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090ab540847a057389673b8c5ef5c0bb
https://doi.org/10.1086/424999

’n Oorsig van die bepaling van die vroeë bakterisidiese aktiwiteit van verskeie antituberkulosemiddels

Autor: P. R. Donald, F. A. Sirgel, A. Venter, P. B. Fourie, D. P. Parkin Parkin, H. I. Seifart, B. W. van de Wal, J. S. Maritz

Publikováno v: South African Journal of Science and Technology, Vol 22, Iss 2&3, Pp 79-88 (2003)
South African Journal of Science and Technology, Vol 22, Iss 2/3, Pp 79-88 (2003)

Die vroeë bakterisidiese aktiwiteit (VBA) van ’n antituberkulosemiddel is die daaglikse afname van M tuberculosis in log10 kolonievormende eenhede per ml sputum, tydens die eerste twee dae van behandeling met die middel. Dit weerspieël die vermo�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0278d09e7266c4fb99772c5bb35943fa
http://www.satnt.ac.za/index.php/satnt/article/view/215

Diagnostic tools in tuberculous pleurisy: a direct comparative study: 1

Autor: Andreas H. Diacon, Juanita Bezuidenhout, B. W. Van de Wal, C Wyser, Chris T. Bolliger, Gerhard Walzl, JP Smedema

Publikováno v: European Respiratory Journal. 22:589-591

Thoracoscopy is the most accurate yet most expensive tool for establishing the diagnosis of tuberculous (TB) pleurisy. However, most high TB-incidence regions have limited financial resources, lack the infrastructure needed for routine thoracoscopy a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::228ea17eb3a06b03d65d61d6fc0d8459
https://doi.org/10.1183/09031936.03.00017103a

Early bactericidal activity of antituberculosis agents

Autor: B. W. Van de Wal, P. B. Fourie, D. P. Parkin, H. I. Seifart, Amour Venter, J.S. Maritz, F. A. Sirgel, Peter R. Donald

Publikováno v: Expert review of anti-infective therapy. 1(1)

The early bactericidal activity (EBA) of an antituberculosis agent is arbitrarily defined as the fall in log(10) colony forming units (cfu) of Mycobacterium tuberculosis per ml sputum per day during the first 2 days of treatment. Determining the EBA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ff7ab0e3a98e3d1928431ee8d6deb7
https://pubmed.ncbi.nlm.nih.gov/15482107

The early bactericidal activity of streptomycin

Autor: P R, Donald, F A, Sirgel, A, Venter, E, Smit, D P, Parkin, B W, Van de Wal, C J, Doré, D A, Mitchison

Publikováno v: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 6(8)

Patients with sputum smear-positive, newly diagnosed pulmonary tuberculosis studied at Tygerburg Hospital, Cape Town, for their early response to streptomycin (SM).To determine the standard early bactericidal activity (EBA), namely the fall in viable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::425f722db14fbfe2950b2b6452600ccd
https://pubmed.ncbi.nlm.nih.gov/12150481