Zobrazeno 1 - 10
of 89
pro vyhledávání: '"B. Vaughan Hudson"'
Publikováno v:
European Journal of Cancer. 36:384-389
The prognosis of Hodgkin's disease (HD) has improved during the last 30 years. This study was planned to analyse long-term survival of HD patients and to compare survival rates estimated from clinical trials and population-based data. Individual data
Autor:
Walter M Gregory, J. K. Wood, Adrian C. Newland, Peter Hoskin, K. A. MacLennan, Donald Milligan, Paul Smith, David C. Linch, G. Vaughan Hudson, B. Vaughan Hudson, David Cunningham, P. A. Stevenson, Barry W. Hancock
Publikováno v:
Annals of Oncology. 11:S87-S90
Background: Between 1987 and 1991, the British National Lymphoma Investigation randomized 459 patients with non-Hodgkin's lymphoma with a large-cell component to either CHOP or the PACEBOM regimen. Patients and methods: Four hundred fifty-nine eligib
Autor:
L Anderson, KA MacLennan, D Mason, B. Vaughan Hudson, M Burke, G. Vaughan Hudson, Peter Selby, ME Hill, David C. Linch, Paul A. Clarke, David Cunningham, F Di Stefano
Publikováno v:
Europe PubMed Central
The Bcl-2 protein is capable of preventing apoptosis, and in vitro evidence suggests a role in drug resistance. It is expressed and the gene is rearranged in a proportion of cases of large-cell non-Hodgkin's lymphoma (NHL), but the clinical significa
Autor:
Donald Milligan, P Hoskin, David C. Linch, G. Vaughan Hudson, Barry W. Hancock, L Anderson, B. Vaughan Hudson, P. A. Stevenson, Adrian C. Newland, K. A. MacLennan, David Cunningham, J. K. Wood, Walter M Gregory
Publikováno v:
British Journal of Cancer
A combination of cyclophosphamide, doxorubicin, vincristine and prednisolone (CHOP) has been a standard therapy for histologically aggressive non-Hodgkin's lymphomas for over 20 years, but several newer regimens, referred to as second or third genera
Publikováno v:
British Journal of Cancer
A retrospective analysis was performed of 451 adult patients with clinical stage 1/1E non-Hodgkin's lymphoma treated initially with radiotherapy alone. Histopathologically 208 patients had low-grade disease and 243 patients high-grade disease. The co
Publikováno v:
British Journal of Cancer
The risks of second primary cancer were analysed in 2846 patients with Hodgkin's disease treated within the British National Lymphoma Investigation during 1970-87. The relative risk (RR) of leukaemia was significantly greater in women (RR = 30.1; 95%
Publikováno v:
British Journal of Cancer
Records of 2,145 cases of Hodgkin's disease in England and Wales treated by the British National Lymphoma Investigation during 1970-84 were sought in the national and regional cancer registers. One thousand eight hundred and eight-six (88%) were reco
Publikováno v:
Hematological Oncology. 10:81-86
The British National Lymphoma Investigation (BNLI) has assessed the use of an IMVP-16 regimen (ifosfamide, methotrexate, VP-16) in 46 patients with high grade non-Hodgkin's lymphoma (NHL) who on first-line chemotherapy either failed to attain a compl
Autor:
K. A. MacLennan, A.M. Jelliffe, G. Vaughan Hudson, J.L. Haybittle, B. Vaughan Hudson, M.H. Bennett, Barry W. Hancock
Publikováno v:
British Journal of Cancer
From 1979-1983, 299 patients with stage III or IV Hodgkin's disease (HD) were randomised to receive cyclical chemotherapy with MOPP (mustine, Oncovin, procarbazine, prednisone) or LOPP (Leukeran substituted for mustine). Two hundred and ninety patien
Publikováno v:
Annals of Oncology. 2:83-92
Twenty-two of 3033 patients with Hodgkin’s disease (HD) randomised into the clinical trials of the BNLI have developed non-Hodgkin’s lymphomas (NHLs) at periods up to 16 years after presentation (1 simultaneous and 1 composite), giving an inciden