Zobrazeno 1 - 10
of 197
pro vyhledávání: '"B. Terlain"'
Publikováno v:
ChemInform. 23
Autor:
B. Terlain, Pierre Gillet, P. Netter, J Y Jouzeau, A. Bousseau, P. Fener, Charrière G, E. Drelon
Publikováno v:
Inflammopharmacology. 1:263-282
Recent studies have reported the ambivalent properties of IL-1, in that it increases or decreases experimental arthritis depending on the dose, the mode, the site, the duration of administration, and the animal model used. In a first experiment we in
Publikováno v:
Journal of Clinical Investigation. 87:1936-1944
Bronchoconstriction (BC) is the main feature of anaphylaxis in the guinea pig. Since LPS induces lung inflammation and antigen-induced BC depends on the endogenous formation of histamine and arachidonate metabolites, we studied whether LPS might modu
Autor:
P E, Poleni, A, Bianchi, S, Etienne, M, Koufany, S, Sebillaud, P, Netter, B, Terlain, J Y, Jouzeau
Publikováno v:
Osteoarthritis and cartilage. 15(5)
To investigate the potency of selective agonists of peroxisome proliferators-activated receptors' (PPAR) isotypes (alpha, beta/delta or gamma) to modulate the stimulating effect of transforming growth factor-beta1 (TGF-beta1) on proteoglycans' (PGs)
Publikováno v:
Annales pharmaceutiques francaises. 63(3)
The contribution of leptin, as a possible link between osteoarthritis (OA) and obesity, was studied in cartilage and synovial fluid samples obtained from osteoarthritic patients. Its effect on cartilage was evaluated in rats after intraarticular inje
Autor:
J N, Gouze, K, Bordji, S, Gulberti, B, Terlain, P, Netter, J, Magdalou, S, Fournel-Gigleux, M, Ouzzine
Publikováno v:
Arthritis and rheumatism. 44(2)
To assess the variations of galactose-beta-1,3-glucuronosyltransferase I (GlcAT-I) expression related to the decrease in proteoglycan synthesis mediated by interleukin-1beta (IL-1beta) in rat chondrocytes, and to evaluate the influence of glucosamine
Publikováno v:
Journal of neuroendocrinology. 12(8)
The limited entry of interleukin-1beta (IL-1beta) into the central nervous system has led to the hypothesis that IL-1beta acts, through IL-1beta receptors located notably on endothelial cells, on the release of prostaglandins which in turn stimulate
Autor:
K, Bordji, J P, Grillasca, J N, Gouze, J, Magdalou, H, Schohn, J M, Keller, A, Bianchi, M, Dauça, P, Netter, B, Terlain
Publikováno v:
The Journal of biological chemistry. 275(16)
Peroxisome proliferator-activated receptor (PPAR) alpha, PPARgamma, and retinoid acid receptor-related orphan receptor (ROR) alpha are members of the nuclear receptor superfamily of ligand-activated transcription factors. Although they play a key rol
Publikováno v:
Presse medicale (Paris, France : 1983). 29(5)
POSSIBLE INFLAMMATORY MECHANISMS: Alzheimer's disease (AD) is a degenerative disease of the brain including possibly inflammatory mechanisms, as illustrated by the presence of activated microglial cells in the periphery of senile plaques and neurofib
Autor:
E, Decaris, C, Guingamp, M, Chat, L, Philippe, J P, Grillasca, A, Abid, A, Minn, P, Gillet, P, Netter, B, Terlain
Publikováno v:
Arthritis and rheumatism. 42(9)
To investigate involvement of the nervous system in ipsilateral and contralateral joint inflammation.Freund's complete adjuvant (CFA; 1 mg or 1 microg) was injected unilaterally and the messages (a) from the hind paw to the ipsilateral and contralate