Výsledky vyhledávání - "B. T. Prabhakar"

Characterization of antioxidant, anti-cancer, and immunomodulatory functions of partially purified garlic (Allium sativum L.) lectin

Autor: null Shruthishree D. Padiyappa, null Hemavathi Avalappa, null Yeldur P. Venkatesh, null Nagaraj Parisara, null B. T. Prabhakar, null Pramod.S.N.

Publikováno v: Biomedicine. 42:703-712

Introduction and Aim: The metabolic and oxidative stress induces highly reactive free radicals that are known to harm normal physiology and play a role in the development of cancer. Elevated levels of these free radicals contribute to excessive neova

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da239b4cd2669941ae3d4f8ec80cf4ea
https://doi.org/10.51248/.v42i4.1862

Zobrazit plný text záznamu

Antiproliferative pharmacophore azo-hydrazone analogue BT-1F exerts death signalling pathway targeting STAT3 in solid tumour

Autor: Banumathi, Ankith, Sherapura, Vikas H, Malojirao, Zabiulla, B S, Sharath, Prabhu, Thirusangu, Riaz, Mahmood, N Suchetha, Kumari, Shrinath M, Baliga, Shaukath Ara, Khanum, B T, Prabhakar

Publikováno v: Pharmacological Reports. 74:353-365

Anomalous activation of intra-cellular signalling cascades confers neoplastic properties on malignant cells. The JAK2/STAT3 proteins play a pivotal role in the pathogenesis of most of the solid malignancies. The over expression of STAT3 in these tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7865f20c48a11fbce125fbfc6ba2ea7f
https://doi.org/10.1007/s43440-021-00345-w

Zobrazit plný text záznamu

In Silico Characterization of a Transcript Code Based Screening of Antimicrobial Peptide from Trichogramma chilonis

Autor: P. Niranjana, H. S. Santosh Kumar, O. Z. Kerima, B. T. Prabhakar, S. N. Pramod, S. V. Sunil

Publikováno v: International Journal of Peptide Research and Therapeutics. 27:2861-2872

Antimicrobial peptides (AMPs) from insects possess potent antimicrobial properties against various microbial related diseases. Trichogramma chilonis is a type of egg endoparasitoid wasp, well known as a biological control agent for pests that express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b44af69331ad02648a06e72b3d7821d
https://doi.org/10.1007/s10989-021-10295-9

Zobrazit plný text záznamu

Plný text ve formátu HTML

A systems biology investigation of curcumin potency against TGF-β-induced EMT signaling in lung cancer

Autor: Shivananda Kandagalla, B. S. Sharath, Ankith Sherapura, Maria Grishina, Vladimir Potemkin, Julian Lee, Gopalakrishna Ramaswamy, B. T. Prabhakar, Manjunatha Hanumanthappa

Publikováno v: 3 Biotech. 12(11)

Curcumin (diferuloylmethane) is bioactive phenolic compound which exerts diverse antimetastatic effect. Several studies have reported the antimetastatic effect of curcumin by its ability to modulate the epithelial-to-mesenchymal transition (EMT) proc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa37d9c68427c150da5ab183561b708
https://pubmed.ncbi.nlm.nih.gov/36276461

Zobrazit plný text záznamu

Plný text ve formátu HTML

Anti-neoplastic pharmacophore benzophenone-1 coumarin (BP-1C) targets JAK2 to induce apoptosis in lung cancer

Autor: Ankith, Sherapura, Vikas H, Malojirao, Prabhu, Thirusangu, B S, Sharath, Shivananda, Kandagalla, V, Vigneshwaran, Jurica, Novak, Lakshmi, Ranganatha, Y L, Ramachandra, Shrinath M, Baliga, Shaukath Ara, Khanum, B T, Prabhakar

Publikováno v: Apoptosis : an international journal on programmed cell death. 27(1-2)

Reigning of the abnormal gene activation associated with survival signalling in lung cancer leads to the anomalous growth and therapeutic failure. Targeting specific cell survival signalling like JAK2/STAT3 nexus has become a major focus of investiga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a050440cf553695ca907bfb679569537
https://pubmed.ncbi.nlm.nih.gov/34837562

Zobrazit plný text záznamu

Modulation of DNA damage response by targeting ATM kinase using newly synthesized di-phenoxy acetamide (DPA) analogs to induce anti-neoplasia

Autor: Fares Hezam, Al-Ostoot, Ankith, Sherapura, Vikas H, Malojirao, Prabhu, Thirusangu, Tahani I, Al-Muhimeed, Shaukath Ara, Khanum, B T, Prabhakar

Publikováno v: Pharmacological reports : PR. 73(5)

Imbalance and instability in the structure of the DNA have become major characteristics of cancer. In response to DNA damage, DNA damage response (DDR) protein, ataxia telangiectasia mutated (ATM), plays a pivotal role in the modulation of regulatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::58f84844a84d9bcf40f688cff92f0692
https://pubmed.ncbi.nlm.nih.gov/34109572

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání