Herpes simplex virus type 1-induced hemagglutination: glycoprotein C mediates virus binding to erythrocyte surface heparan sulfate

Autor: S Jeansson, B Svennerholm, S Olofsson, E Trybala, T Bergström, J L Goodman

Publikováno v: Europe PubMed Central

We recently reported that herpes simplex virus type 1 (HSV-1) can cause agglutination of murine erythrocytes (E. Trybala, Z. Larski, and J. Wisniewski, Arch. Virol. 113:89-94, 1990). We now demonstrate that the mechanism of this hemagglutination is g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6319593fe73f0d9d22a3dd1e8fe8508c
https://doi.org/10.1128/jvi.67.3.1278-1285.1993

Discrimination of herpes simplex virus types 1 and 2 cerebral infections in a rat model

Autor: N. Conradi, T. Bergström, B Svennerholm, A. Vahlne, P Horal

Publikováno v: Acta Neuropathologica. 82:395-401

A rat model was used to evaluate intertypic differences after intracranial (i.c.) inoculation of herpes simplex virus (HSV) types 1 and 2 strains with regard to neurovirulence and neuropathology, and influence of age on susceptibility. In adult rats,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7deba09342bc53ad67abe74a154c00
https://doi.org/10.1007/bf00296551

A randomized, double-blind, placebo-controlled MRI study of anti-herpes virus therapy in MS

Autor: Johannes Jakobsen, Oluf Andersen, B. Svennerholm, Tove Christensen, Sven Haahr, E. Bech, Tomas Bergström, Jan Lycke, Sven Ekholm, Clas Malmeström, Per Höllsberg, H. J. Hansen, P. Gadeberg

Publikováno v: ResearcherID
Aarhus University
Bech, E, Lycke, J, Gadeberg, P, Hansen, H J, Malmeström, C, Andersen, O, Christensen, T, Ekholm, S, Haahr, S, Höllsberg, P, Bergström, T, Svennerholm, B & Jakobsen, J 2002, ' A randomized, double-blind, placebo-controlled MRI study of anti-herpes virus therapy in MS ', Neurology, vol. 58, pp. 31-36 .

Objective: To evaluate the effect of treatment with the antiherpes drug valacyclovir on MRI-evident lesions in patients with relapsing-remitting MS in a phase 2, randomized, double-blind, placebo-controlled study. Background: It has been postulated f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3d0da45d6d50af9e2b602363135412
https://pubmed.ncbi.nlm.nih.gov/11937004

The nontoxic tripeptide glycyl-prolyl-glycine amide inhibits the replication of human immunodeficiency virus type 1

Autor: J, Su, E, Andersson, P, Horal, M H, Naghavi, A, Palm, Y P, Wu, K, Eriksson, M, Jansson, H, Wigzell, B, Svennerholm, A, Vahlne

Publikováno v: Journal of human virology. 4(1)

To determine whether short peptides corresponding to the RGPGR motif of the V3 loop of gp 120 have anti-human immunodeficiency virus type 1 (anti-HIV-1) activity.Short peptides were tested against the HIV-1 laboratory strains and clinical isolates.Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f36a4e1f6a52969ae403222d6a651c9c
https://pubmed.ncbi.nlm.nih.gov/11213928

Interaction between pseudorabies virus and heparin/heparan sulfate. Pseudorabies virus mutants differ in their interaction with heparin/heparan sulfate when altered for specific glycoprotein C heparin-binding domain

Autor: E, Trybala, T, Bergström, D, Spillmann, B, Svennerholm, S J, Flynn, P, Ryan

Publikováno v: The Journal of biological chemistry. 273(9)

Cell surface heparan sulfate serves as an initial receptor for a number of herpesviruses including pseudorabies virus (PrV). It has been demonstrated that the heparan sulfate-binding domain of PrV glycoprotein C is composed of three discrete clusters

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be27dee1ea696e2ed5abc501d49cb78d
https://pubmed.ncbi.nlm.nih.gov/9478954