Zobrazeno 1 - 10
of 1 915
pro vyhledávání: '"B. Smit"'
Autor:
T. Schietinger, M. Pedrozzi, M. Aiba, V. Arsov, S. Bettoni, B. Beutner, M. Calvi, P. Craievich, M. Dehler, F. Frei, R. Ganter, C. P. Hauri, R. Ischebeck, Y. Ivanisenko, M. Janousch, M. Kaiser, B. Keil, F. Löhl, G. L. Orlandi, C. Ozkan Loch, P. Peier, E. Prat, J.-Y. Raguin, S. Reiche, T. Schilcher, P. Wiegand, E. Zimoch, D. Anicic, D. Armstrong, M. Baldinger, R. Baldinger, A. Bertrand, K. Bitterli, M. Bopp, H. Brands, H. H. Braun, M. Brönnimann, I. Brunnenkant, P. Chevtsov, J. Chrin, A. Citterio, M. Csatari Divall, M. Dach, A. Dax, R. Ditter, E. Divall, A. Falone, H. Fitze, C. Geiselhart, M. W. Guetg, F. Hämmerli, A. Hauff, M. Heiniger, C. Higgs, W. Hugentobler, S. Hunziker, G. Janser, B. Kalantari, R. Kalt, Y. Kim, W. Koprek, T. Korhonen, R. Krempaska, M. Laznovsky, S. Lehner, F. Le Pimpec, T. Lippuner, H. Lutz, S. Mair, F. Marcellini, G. Marinkovic, R. Menzel, N. Milas, T. Pal, P. Pollet, W. Portmann, A. Rezaeizadeh, S. Ritt, M. Rohrer, M. Schär, L. Schebacher, St. Scherrer, V. Schlott, T. Schmidt, L. Schulz, B. Smit, M. Stadler, B. Steffen, L. Stingelin, W. Sturzenegger, D. M. Treyer, A. Trisorio, W. Tron, C. Vicario, R. Zennaro, D. Zimoch
Publikováno v:
Physical Review Accelerators and Beams, Vol 19, Iss 10, p 100702 (2016)
The SwissFEL Injector Test Facility operated at the Paul Scherrer Institute between 2010 and 2014, serving as a pilot plant and test bed for the development and realization of SwissFEL, the x-ray Free-Electron Laser facility under construction at the
Externí odkaz:
https://doaj.org/article/11e79eb3626e4915ac18ddb00ef9812e
Blue Native PAGE–Antibody Shift in Conjunction with Mass Spectrometry to Reveal Protein Subcomplexes
Autor:
Miao Chen, Frank Koopmans, Iryna Paliukhovich, Sophie J. F. van der Spek, Jian Dong, August B. Smit, Ka Wan Li
Publikováno v:
International Journal of Molecular Sciences, 24(8):7632, 1-14. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7632
Chen, M, Koopmans, F, Paliukhovich, I, van der Spek, S J F, Dong, J, Smit, A B & Li, K W 2023, ' Blue Native PAGE–Antibody Shift in Conjunction with Mass Spectrometry to Reveal Protein Subcomplexes : Detection of a Cerebellar α1/α6-Subunits Containing γ-Aminobutyric Acid Type A Receptor Subtype ', International Journal of Molecular Sciences, vol. 24, no. 8, 7632, pp. 1-14 . https://doi.org/10.3390/ijms24087632
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7632
Chen, M, Koopmans, F, Paliukhovich, I, van der Spek, S J F, Dong, J, Smit, A B & Li, K W 2023, ' Blue Native PAGE–Antibody Shift in Conjunction with Mass Spectrometry to Reveal Protein Subcomplexes : Detection of a Cerebellar α1/α6-Subunits Containing γ-Aminobutyric Acid Type A Receptor Subtype ', International Journal of Molecular Sciences, vol. 24, no. 8, 7632, pp. 1-14 . https://doi.org/10.3390/ijms24087632
The pentameric γ-Aminobutyric acid type A receptors (GABAARs) are ligand-gated ion channels that mediate the majority of inhibitory neurotransmission in the brain. In the cerebellum, the two main receptor subtypes are the 2α1/2β/γ and 2α6/2β/δ
Autor:
Merel O. Mol, Suzanne S. M. Miedema, Shamiram Melhem, Ka Wan Li, Frank Koopmans, Harro Seelaar, Kurt Gottmann, Volkmar Lessmann, Netherlands Brain Bank, August B. Smit, John C. van Swieten, Jeroen G. J. van Rooij
Publikováno v:
Acta neuropathologica communications, 10(1). BioMed Central
Acta neuropathologica communications, 10(1):190. BioMed Central Ltd.
Acta Neuropathologica Communications, 10:190, 1-14. BioMed Central
Mol, M O, Miedema, S S M, Melhem, S, Li, K W, Koopmans, F, Seelaar, H, Gottmann, K, Lessmann, V, Bank, N B, Smit, A B, van Swieten, J C & van Rooij, J G J 2022, ' Proteomics of the dentate gyrus reveals semantic dementia specific molecular pathology ', Acta Neuropathologica Communications, vol. 10, 190, pp. 1-14 . https://doi.org/10.1186/s40478-022-01499-1
Acta neuropathologica communications, 10(1):190. BioMed Central Ltd.
Acta Neuropathologica Communications, 10:190, 1-14. BioMed Central
Mol, M O, Miedema, S S M, Melhem, S, Li, K W, Koopmans, F, Seelaar, H, Gottmann, K, Lessmann, V, Bank, N B, Smit, A B, van Swieten, J C & van Rooij, J G J 2022, ' Proteomics of the dentate gyrus reveals semantic dementia specific molecular pathology ', Acta Neuropathologica Communications, vol. 10, 190, pp. 1-14 . https://doi.org/10.1186/s40478-022-01499-1
Semantic dementia (SD) is a clinical subtype of frontotemporal dementia consistent with the neuropathological diagnosis frontotemporal lobar degeneration (FTLD) TDP type C, with characteristic round TDP-43 protein inclusions in the dentate gyrus. Des
Autor:
Annemiek A. Van Berkel, Frank Koopmans, Miguel Angel Gonzalez-Lozano, Hanna C. A. Lammertse, Femke Feringa, Julien Bryois, Patrick F. Sullivan, August B. Smit, Ruud F. Toonen, Matthijs Verhage
Publikováno v:
eNeuro, 9(6):ENEURO.0186-22.2022. Society for Neuroscience
Van Berkel, A A, Koopmans, F, Gonzalez-Lozano, M A, Lammertse, H C A, Feringa, F, Bryois, J, Sullivan, P F, Smit, A B, Toonen, R F & Verhage, M 2022, ' Dysregulation of Synaptic and Developmental Transcriptomic/Proteomic Profiles upon Depletion of MUNC18-1 ', eNeuro, vol. 9, no. 6, pp. 1-14 . https://doi.org/10.1523/ENEURO.0186-22.2022
eNeuro, 9(6), 1-14. Society for Neuroscience
van Berkel, A A, Koopmans, F, Gonzalez-Lozano, M A, Lammertse, H C A, Feringa, F, Bryois, J, Sullivan, P F, Smit, A B, Toonen, R F & Verhage, M 2022, ' Dysregulation of Synaptic and Developmental Transcriptomic/Proteomic Profiles upon Depletion of MUNC18-1 ', eNeuro, vol. 9, no. 6, ENEURO.0186-22.2022 . https://doi.org/10.1523/ENEURO.0186-22.2022
Van Berkel, A A, Koopmans, F, Gonzalez-Lozano, M A, Lammertse, H C A, Feringa, F, Bryois, J, Sullivan, P F, Smit, A B, Toonen, R F & Verhage, M 2022, ' Dysregulation of Synaptic and Developmental Transcriptomic/Proteomic Profiles upon Depletion of MUNC18-1 ', eNeuro, vol. 9, no. 6, pp. 1-14 . https://doi.org/10.1523/ENEURO.0186-22.2022
eNeuro, 9(6), 1-14. Society for Neuroscience
van Berkel, A A, Koopmans, F, Gonzalez-Lozano, M A, Lammertse, H C A, Feringa, F, Bryois, J, Sullivan, P F, Smit, A B, Toonen, R F & Verhage, M 2022, ' Dysregulation of Synaptic and Developmental Transcriptomic/Proteomic Profiles upon Depletion of MUNC18-1 ', eNeuro, vol. 9, no. 6, ENEURO.0186-22.2022 . https://doi.org/10.1523/ENEURO.0186-22.2022
Absence of presynaptic protein MUNC18-1 (gene:Stxbp1) leads to neuronal cell death at an immature stage before synapse formation. Here, we performed transcriptomic and proteomic profiling of immatureStxbp1knock-out (KO) cells to discover which cellul
Autor:
Josephine B. Smit, Charlotte E. Searle, Hannah M. Buchanan‐Smith, Paolo Strampelli, Lameck Mkuburo, Victor A. Kakengi, Edward M. Kohi, Amy J. Dickman, Phyllis C. Lee
Publikováno v:
African Journal of Ecology. 61:64-76
Autor:
Mandy S. J. Kater, Katharina F. Baumgart, Aina Badia‐Soteras, Tim S. Heistek, Karen E. Carney, A. Jacob Timmerman, Jan R. T. van Weering, August B. Smit, Marjo S. van der Knaap, Huibert D. Mansvelder, Mark H. G. Verheijen, Rogier Min
Publikováno v:
Kater, M S J, Baumgart, K F, Badia-Soteras, A, Heistek, T S, Carney, K E, Timmerman, A J, van Weering, J R T, Smit, A B, van der Knaap, M S, Mansvelder, H D, Verheijen, M H G & Min, R 2023, ' A novel role for MLC1 in regulating astrocyte–synapse interactions ', GLIA, vol. 71, no. 7, pp. 1770-1785 . https://doi.org/10.1002/glia.24368
Glia, 71(7), 1770-1785. John Wiley and Sons Inc.
GLIA, 71(7), 1770-1785. John Wiley and Sons Inc.
Kater, M S J, Baumgart, K F, Badia-Soteras, A, Heistek, T S, Carney, K E, Timmerman, A J, van Weering, J R T, Smit, A B, van der Knaap, M S, Mansvelder, H D, Verheijen, M H G & Min, R 2023, ' A novel role for MLC1 in regulating astrocyte–synapse interactions ', Glia, vol. 71, no. 7, pp. 1770-1785 . https://doi.org/10.1002/glia.24368
Glia, 71(7), 1770-1785. John Wiley and Sons Inc.
GLIA, 71(7), 1770-1785. John Wiley and Sons Inc.
Kater, M S J, Baumgart, K F, Badia-Soteras, A, Heistek, T S, Carney, K E, Timmerman, A J, van Weering, J R T, Smit, A B, van der Knaap, M S, Mansvelder, H D, Verheijen, M H G & Min, R 2023, ' A novel role for MLC1 in regulating astrocyte–synapse interactions ', Glia, vol. 71, no. 7, pp. 1770-1785 . https://doi.org/10.1002/glia.24368
Loss of function of the astrocyte membrane protein MLC1 is the primary genetic cause of the rare white matter disease Megalencephalic Leukoencephalopathy with subcortical Cysts (MLC), which is characterized by disrupted brain ion and water homeostasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33cbe10cd35672d6014c75fbbae2d06
https://research.vumc.nl/en/publications/4a3453d2-881d-4b24-bf30-c4e9ae534160
https://research.vumc.nl/en/publications/4a3453d2-881d-4b24-bf30-c4e9ae534160
Autor:
Evangelia Thanou, Frank Koopmans, Débora Pita-Illobre, Remco V. Klaassen, Berna Özer, Ioannis Charalampopoulos, August B. Smit, Ka Wan Li
Publikováno v:
Cells; Volume 12; Issue 9; Pages: 1242
Cells, 12(9):1242. MDPI Multidisciplinary Digital Publishing Institute
Thanou, E, Koopmans, F, Pita-Illobre, D, Klaassen, R V, Özer, B, Charalampopoulos, I, Smit, A B & Li, K W 2023, ' Suspension TRAPping Filter (sTRAP) Sample Preparation for Quantitative Proteomics in the Low µg Input Range Using a Plasmid DNA Micro-Spin Column : Analysis of the Hippocampus from the 5xFAD Alzheimer’s Disease Mouse Model ', Cells, vol. 12, no. 9, 1242 . https://doi.org/10.3390/cells12091242
Cells, 12(9):1242. MDPI Multidisciplinary Digital Publishing Institute
Thanou, E, Koopmans, F, Pita-Illobre, D, Klaassen, R V, Özer, B, Charalampopoulos, I, Smit, A B & Li, K W 2023, ' Suspension TRAPping Filter (sTRAP) Sample Preparation for Quantitative Proteomics in the Low µg Input Range Using a Plasmid DNA Micro-Spin Column : Analysis of the Hippocampus from the 5xFAD Alzheimer’s Disease Mouse Model ', Cells, vol. 12, no. 9, 1242 . https://doi.org/10.3390/cells12091242
Suspension TRAPping filter (sTRAP) is an attractive sample preparation method for proteomics studies. The sTRAP protocol uses 5% SDS that maximizes protein solubilization. Proteins are trapped on a borosilicate glass membrane filter, where SDS is sub
Autor:
Simon A. Hardwick, Wen Hu, Anoushka Joglekar, Li Fan, Paul G. Collier, Careen Foord, Jennifer Balacco, Samantha Lanjewar, Maureen McGuirk Sampson, Frank Koopmans, Andrey D. Prjibelski, Alla Mikheenko, Natan Belchikov, Julien Jarroux, Anne Bergstrom Lucas, Miklós Palkovits, Wenjie Luo, Teresa A. Milner, Lishomwa C. Ndhlovu, August B. Smit, John Q. Trojanowski, Virginia M. Y. Lee, Olivier Fedrigo, Steven A. Sloan, Dóra Tombácz, M. Elizabeth Ross, Erich Jarvis, Zsolt Boldogkői, Li Gan, Hagen U. Tilgner
Publikováno v:
Nature Biotechnology, 40(7), 1082-1092. Nature Publishing Group
Hardwick, S A, Hu, W, Joglekar, A, Fan, L, Collier, P G, Foord, C, Balacco, J, Lanjewar, S, Sampson, M M G, Koopmans, F, Prjibelski, A D, Mikheenko, A, Belchikov, N, Jarroux, J, Lucas, A B, Palkovits, M, Luo, W, Milner, T A, Ndhlovu, L C, Smit, A B, Trojanowski, J Q, Lee, V M Y, Fedrigo, O, Sloan, S A, Tombácz, D, Ross, M E, Jarvis, E, Boldogkői, Z, Gan, L & Tilgner, H U 2022, ' Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue ', Nature Biotechnology, vol. 40, no. 7, pp. 1082-1092 . https://doi.org/10.1038/s41587-022-01231-3
Hardwick, S A, Hu, W, Joglekar, A, Fan, L, Collier, P G, Foord, C, Balacco, J, Lanjewar, S, Sampson, M M G, Koopmans, F, Prjibelski, A D, Mikheenko, A, Belchikov, N, Jarroux, J, Lucas, A B, Palkovits, M, Luo, W, Milner, T A, Ndhlovu, L C, Smit, A B, Trojanowski, J Q, Lee, V M Y, Fedrigo, O, Sloan, S A, Tombácz, D, Ross, M E, Jarvis, E, Boldogkői, Z, Gan, L & Tilgner, H U 2022, ' Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue ', Nature Biotechnology, vol. 40, no. 7, pp. 1082-1092 . https://doi.org/10.1038/s41587-022-01231-3
Single-nuclei RNA sequencing characterizes cell types at the gene level. However, compared to single-cell approaches, many single-nuclei cDNAs are purely intronic, lack barcodes and hinder the study of isoforms. Here we present single-nuclei isoform
Autor:
Janssen M. Kotah, Mandy S.J. Kater, Lianne Hoeijmakers, Niek Brosens, Sylvie L. Lesuis, Roberta Tandari, Luca Marchetto, Ella Yusaf, August B. Smit, Paul J. Lucassen, Harm Krugers, Mark H.G. Verheijen, Aniko Korosi
Epidemiological evidence indicates that early life stress (ES) exposure increases the risk for later-life diseases, such as Alzheimer’s disease (AD). Accordingly, we and others have shown that ES aggravates the development of, and response to, amyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2fd488927132cb9240305eb7ef4b25c
https://doi.org/10.1101/2023.04.20.537660
https://doi.org/10.1101/2023.04.20.537660