Zobrazeno 1 - 9
of 9
pro vyhledávání: '"B. Scott Ferguson"'
Autor:
Ali Bashir, Qin Yang, Jinpeng Wang, Stephan Hoyer, Wenchuan Chou, Cory McLean, Geoff Davis, Qiang Gong, Zan Armstrong, Junghoon Jang, Hui Kang, Annalisa Pawlosky, Alexander Scott, George E. Dahl, Marc Berndl, Michelle Dimon, B. Scott Ferguson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Current aptamer discovery approaches are unable to probe the complete space of possible sequences. Here, the authors use machine learning to facilitate the development of DNA aptamers with improved binding affinities, and truncate them without signif
Externí odkaz:
https://doaj.org/article/9508da0079cf405d9f6f644c1119f62f
Autor:
Tyler Chozinski, B. Scott Ferguson, William Fisher, Shencheng Ge, Qiang Gong, Hui Kang, John McDermott, Alexander Scott, Wentao Shi, Jeremiah J. Trausch, Thorsten Verch, Matthew Vukovich, Jinpeng Wang, J. Emma Wu, Qin Yang
Publikováno v:
Analytical Chemistry. 94:6146-6155
Global deployment of vaccines poses significant challenges in the distribution and use of the accompanying immunoassays, one of the standard methods for quality control of vaccines, particularly when establishing assays in countries worldwide to supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5ef421336b74466f4864860f1d3417
https://doi.org/10.1021/acs.analchem.1c05093
https://doi.org/10.1021/acs.analchem.1c05093
Autor:
Qiang Gong, Matthew Vukovich, William J. Greenleaf, Jingwen Yu, Remy Lagrois, Alexander Scott, Jinpeng Wang, John McDermott, B. Scott Ferguson, Michael Eisenstein, H. Tom Soh, Qin Yang
Publikováno v:
Angewandte Chemie. 129:762-765
Aptamers are a promising class of affinity reagents because they are chemically synthesized, making them highly reproducible and distributable as sequence information rather than a physical entity. Although many high-quality aptamers have been previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d38d3c082d5bf520be69b701e4daae7
https://doi.org/10.1002/ange.201608880
https://doi.org/10.1002/ange.201608880
Autor:
H. Tom Soh, Adriana S. Patterson, Allen H. J. Yang, Michael Eisenstein, Kevin W. Plaxco, Kuangwen Hsieh, B. Scott Ferguson
Publikováno v:
Angewandte Chemie (International ed. in English), vol 53, iss 12
We report the first electrochemical system for the detection of single-nucleotide polymorphisms (SNPs) that can accurately discriminate homozygous and heterozygous genotypes using microfluidics technology. To achieve this, our system performs real-ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f8107797395ba652bec66d471da860
https://doi.org/10.1002/anie.201310059
https://doi.org/10.1002/anie.201310059
Publikováno v:
Angewandte Chemie International Edition. 51:4896-4900
Single-step DNA detection: a microfluidic electrochemical loop mediated isothermal amplification platform is reported for rapid, sensitive, and quantitative detection of pathogen genomic DNA at the point of care. DNA amplification was electrochemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7e7fb03fdbe00ecd4661845bae975f
https://doi.org/10.1002/anie.201109115
https://doi.org/10.1002/anie.201109115
Autor:
Steven F. Buchsbaum, Kuangwen Hsieh, B. Scott Ferguson, H. Tom Soh, Yi Xiao, Ting-Ting Wu, Ren Sun
Publikováno v:
Journal of the American Chemical Society. 133:9129-9135
The ability to obtain sequence-specific genetic information about rare target organisms directly from complex biological samples at the point-of-care would transform many areas of biotechnology. Microfluidics technology offers compelling tools for in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339145bd5a66b66fc355386fa3dd34fd
https://doi.org/10.1021/ja203981w
https://doi.org/10.1021/ja203981w
Publikováno v:
Accounts of chemical research. 48(4)
The capacity to achieve rapid, sensitive, specific, quantitative, and multiplexed genetic detection of pathogens via a robust, portable, point-of-care platform could transform many diagnostic applications. And while contemporary technologies have yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1d3d8c1590ea09ca5acd8ad5af3d5c
https://pubmed.ncbi.nlm.nih.gov/25785632
https://pubmed.ncbi.nlm.nih.gov/25785632
Autor:
Kuangwen Hsieh, Alexis Vallée-Bélisle, Francesco Ricci, B. Scott Ferguson, Andrew J. Bonham, H. Tom Soh, Kevin W. Plaxco
Transcription factor expression levels, which sensitively reflect cellular development and disease state, are typically monitored via cumbersome, reagent-intensive assays that require relatively large quantities of cells. Here, we demonstrate a simpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5bdcea224186249cf9f143911f868e
http://hdl.handle.net/2108/84616
http://hdl.handle.net/2108/84616
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