Zobrazeno 1 - 10
of 1 074
pro vyhledávání: '"B. S. Robinson"'
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 6, Pp 1234-1245 (1996)
Although tumor necrosis factor-alpha (TNF-alpha) has been shown to induce marked changes in the physiology/pathophysiology of cells, little is known about the effects of this cytokine on cellular lipid metabolism. In this study we examined the effect
Externí odkaz:
https://doaj.org/article/c2c632b9498a4bcf80e745fa650282e1
Autor:
Stephen J. Hardy, David W. Johnson, Alf Poulos, B S Robinson, Antonio Ferrante, Katherine J. Clark, Andrew W. Murray
Publikováno v:
Journal of Neurochemistry. 62:1546-1551
A variety of fatty acids including the cis-polyunsaturated very-long-chain fatty acids (VLCFA) (> 22 carbon atoms) common in retina, spermatozoa, and brain were examined for their ability to activate protein kinase C (PKC) purified from rat brain. Ar
Publikováno v:
The Journal of Immunology. 171:4773-4779
We recently reported the synthesis and anti-inflammatory properties of a novel long chain polyunsaturated fatty acid (PUFA) with an oxygen atom in the β-position, β-oxa-21:3 n-3 (Z,Z,Z)-(octadeca-9,12,15-trienyloxy) acetic acid). Our data, from stu
Publikováno v:
European Respiratory Journal. 9:2250-2255
Experimental viral disease studies in volunteers have clarified many aspects of the pathogenesis of human viral disease. Recently, interest has focused on rhinovirus-associated asthma exacerbations, and new volunteer studies have suggested that airwa
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 6, Pp 1234-1245 (1996)
Although tumor necrosis factor-alpha (TNF-alpha) has been shown to induce marked changes in the physiology/pathophysiology of cells, little is known about the effects of this cytokine on cellular lipid metabolism. In this study we examined the effect
Autor:
Antonio Ferrante, S Hardy, B S Robinson, Charles S. T. Hii, David W. Johnson, Andrew W. Murray, Alf Poulos
Publikováno v:
Biochemical Journal. 311:689-697
Fatty acids with more than 22 carbon atoms (very-long-chain fatty acids; VLCFAs) are normal cellular components that have been implicated in the pathophysiology of a number of peroxisomal disorders. To date, however, essentially nothing is known rega
Effect of fatty acid structure on neutrophil adhesion, degranulation and damage to endothelial cells
Publikováno v:
Atherosclerosis. 116:247-259
Neutrophils have been implicated in ischaemic heart disease, unstable angina pectoris and acute myocardial infarction. Alterations in dietary levels of specific 18- and 20-carbon polyunsaturated fatty acids have significant clinical benefits in cardi
Autor:
Antonio Ferrante, Alf Poulos, Lisa G. Smithers, B S Robinson, E. J. Bates, Deborah A. Rathjen
Publikováno v:
Atherosclerosis. 116:125-133
The procoagulant response of endothelium to pathophysiological agents such as tumour necrosis factor α (TNFα) and phorbol myristate acetate (PMA) alters the expression of proteins such as tissue factor. The modulation of such procoagulant activity
Autor:
Charles S. T. Hii, B S Robinson, Deborah A. Rathjen, Antonio Ferrante, Simon Schmidt, Andrew W. Murray, Alf Poulos
Publikováno v:
Carcinogenesis. 16:1505-1511
Polyunsaturated fatty acids have attracted much interest due to their wide spectrum of biological activities which include the modulation of gap junctional communication (GJC). Since gap junctions play critical roles in maintaining the functional int
Publikováno v:
The Journal of Immunology. 153:1754-1761
The effects of exogenous long chain fatty acids (LCFA) and very long chain fatty acids (VLCFA) on superoxide production by human neutrophils were compared. Superoxide production was greater and more rapid in response to arachidonic (20:4 (n-6)), eico