Zobrazeno 1 - 8
of 8
pro vyhledávání: '"B. S. Narayan Reddy"'
Autor:
David E. Thurston, B. S. Praveen Reddy, Philip Wilson Howard, B. S. Narayan Reddy, Ahmed Kamal
Publikováno v:
Tetrahedron. 53:3223-3230
A facile procedure for the preparation of the imine form of the pyrrolo[2,1- c ][1,4]-benzodiazepine ring system by the oxidation of cyclic secondary amine with catalytic amounts of tetra-n-propylammonium perruthenate (TPAP) and N-methylmorpholine N-
Publikováno v:
Tetrahedron Letters. 37:6803-6806
A new facile synthesis of pyrrolo[2,1- c ][1,4]benzodiazepine (PBD) ring system has been achieved by reductive cyclization of the azide employing hexamethyldisilathiane (HMDST). The parent unsubstituted PBD and the natural product DC-81 have also bee
Publikováno v:
Tetrahedron Letters. 37:2281-2284
An efficient synthesis of the imine form of the pyrrolo[2,1-c][1,4]benzodiazepine ring system based on a new reductive cyclization procedure is described. The naturally occuring antibiotic DC-81(5c) and its 5-thio analogue (7c) have also been synthes
Publikováno v:
ChemInform. 30
Publikováno v:
ChemInform. 35
2-Azidopyrrolobenzodiazepines have been synthesized via cyclization of ω-azidocarbonyl compounds employing hexamethyldisilathiane by selectively reducing the aryl azido functionality.
Design and synthesis of C-8 linked pyrrolobenzodiazepine-naphthalimide hybrids as anti-tumour agents
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(15)
The facile synthesis of C-8 linked pyrrolobenzodiazepine–naphthalimide hybrid analogues is described. The compounds are prepared with varying degrees of linker length in order to probe the structural requirements for optimal in vitro anti-tumour ac
Publikováno v:
Synlett. 1999:1251-1252
Autor:
B. S. Narayan Reddy, Ahmed Kamal
Publikováno v:
Chemistry Letters. 27:593-594
Reaction of a variety of azido compounds with N,N-dimethylhydrazine in the presence of a catalytic amount of ferric chloride hexahydrate in methanol results in excellent yields of the corresponding amino compounds. This reductive system is compatible