Zobrazeno 1 - 10
of 36
pro vyhledávání: '"B. S. Handwerger"'
Autor:
I G, Luzina, S P, Atamas, C E, Storrer, L C, daSilva, G, Kelsoe, J C, Papadimitriou, B S, Handwerger
Publikováno v:
Journal of leukocyte biology. 70(4)
The mechanisms of autoantibody production are not well understood. Germinal centers (GC) may be important sites of immune disregulation in autoimmune diseases. In this study, we document the presence of spontaneous GC formation in the spleens of seve
Autor:
I G, Luzina, R H, Knitzer, S P, Atamas, W C, Gause, J C, Papadimitriou, M B, Sztein, C E, Storrer, B S, Handwerger
Publikováno v:
Arthritis and rheumatism. 42(3)
To define the phenotype of cells in the perivascular and vascular infiltrates of Palmerston North (PN) mice and the cytokines that those cells produce.Immunohistologic analysis, flow cytometric analysis, and reverse transcriptase-polymerase chain rea
Publikováno v:
Journal of clinical immunology. 19(1)
PN mice spontaneously develop, with age, a lupus-like disease. The present study further evaluated autoantibody production in female PN mice. As early as 1 month of age, all PN mice had detectable IgM antibodies to dsDNA and ssDNA and two-thirds prod
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(10)
We previously have shown that T cell proliferation in response to a primary signal through the CD3 epsilon chain and a costimulatory signal via the CD28 molecule is impaired in healthy, aged mice. To determine whether age-related alterations in cytok
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(8)
The ability of T cells to proliferate in response to a number of stimuli is impaired in healthy, aged individuals. T cells from young (2 to 4 mo) and aged (20 to 26 mo) mice were stimulated with immobilized anti-CD3 epsilon-chain mAb and soluble anti
Publikováno v:
Transplantation proceedings. 25(1 Pt 1)
Autor:
C S, Via, B S, Handwerger
Publikováno v:
Current opinion in rheumatology. 4(5)
B-cell hyperactivity is characteristic of lupus and appears to be, in many instances, T-cell driven. Recent work continues to examine the paradox of T-cell activation in vivo and depressed T-cell function in vitro. The role of intrinsic B-cell abnorm
Autor:
B S, Handwerger
Publikováno v:
Maryland medical journal (Baltimore, Md. : 1985). 40(2)
Making the diagnosis of connective tissue disease can at times be extremely difficult. Obtaining a complete rheumatological and medical history, and performing a thorough physical examination are absolutely essential. This article has reviewed severa
Publikováno v:
The Journal of Immunology. 139:1532-1540
The role of IL 1 in the activation of IL 4-producing murine T cell clones was investigated by using a calcium ionophore (ionomycin) or a phorbol ester (12-O-tetradecanoylphorbol 13-acetate; TPA) as T cell receptor-independent costimuli. The use of th
Autor:
K. G. M. M. Alberti, J. Iversen, N. J. Christensen, A. Andersson, Claire Jarrousse, Arne Andersson, Claes Hellerström, D. Andreani, G. Tamburrano, S. Tamburrano, S. Gambardella, Joy Ardill, D. A. D. Montgomery, D. R. Hadden, R. Assan, J. R. Attali, A. Selmi, N. Bourdillat, E. Soufflet, J. R. Girard, J. S. Bajaj, G. S. Chinna, S. K. Garg, Baldev Singh, E. O. Balasse, M. A. Neef, W. Beischer, F. Melani, L. Keller, M. Hinz, A. Kroder, V. Maier, E. F. Pfeiffer, M. Bendayan, E. Sandborn, E. Rasio, D. Bensoussan, S. Levy-Toledano, P. Passa, J. Caen, M. Berger, M. N. Goodman, S. A. Hagg, N. B. Ruderman, J. Beyer, U. Cordes, H. Travniczek, W. Heider, K. Schöffling, J. Happ, H. Grimm, W. Pünchera, P. H. Althoff, A. Fröhlich, A. R. Bianco, R. H. Schwartz, B. S. Handwerger, P. J. Blackshear, P. A. H. Holloway, D. H. Williamson, L. Boquist, Bo Hellman, Åke Lernmark, Inge-Bert Täljedabl, P. Bottermann, U. Schweigart, Th. Zilker, W. Hansen, E. Brachet, C. Rogister, Y. Broer, P. Freychet, G. Rosselin, H. Brunengraber, F. Vertongen, M. Boutry, F. Camu, P. Christacopoulos, B. Karamanos, P. Papadimitriou, Ch. Kardatos, Niels Juel Christensen, Bent Neubauer, Jean Christophe, Jacques Winand, Jean Dehaye, G. S. Cuendet, E. G. Loten, B. Jeanrenaud, E. Davis, Ralph E. Yodaiken, L. Yanko, J. B. Herman, S. Duran Garcia, C. Jarrousse, J. Ditzel, Niels Peters Daugaard, Haakon Andersen, J. Egeberg, J. Nerup, O. O. Andersen, H. Kromann, G. Bendixen, J. E. Poulsen, E. Eschwege, S. Falkmer, S. O. Emdin, N. Havu, L. Winbladh Biuw, F. Sundby, J. F. Cutfield, S. M. Cutfield, G. G. Dodson, J. D. Peterson, D. F. Steiner, F. Fallucca, G. Menzinger, M. Iavicoli, G. Federspil, C. de Palo, E. Zago, D. Casara, M. Zaccaria, C. Scandellari, J. -P. Felber, G. Magnenat, B. Curchod, Ph. Pittet, N. Lytras, R. Müller-Hess, C. A. Geser, E. Jéquier, R. W. J. Flanagan, K. D. Buchanan, R. F. Murphy, Ivar Fölling, M. Fromantin, J. Freyria, F. Bressac, W. Geisthövel, U. Niedergerke, K. D. Morgner, B. Willms, H. J. Mitzkat, K. F. Gey, E. Bühler, P. Sommer, H. Georgi, H. Lengsfeld, D. Ghiea, E. Costiner, L. Simionescu, M. Oprescu, V. Grill, E. Cerasi, H. J. G. Gundersen, A. Gutman, J. Adler, D. Bar-Or, A. Gutzeit, B. Guy-Grand, B. Bigorie, Erik Gylfe, Lars-Åke Idahl, Margit Hamosh, Paul Hamosh, Adrian Hart, H. Cohen, J. M. Thorp, C. J. Hedeskov, K. Capito, B. Forruby, J. C. Henquin, A. B. Lambert, A. E. Lambert, K. D. Hepp, R. Renner, H. U. Häring, H. Mehnert, W. Kemmler, G. Löffler, A. Herchuelz, M. Mahy, Emilip Herrera, J. Garcia-Rafanell, J. Morell, Ch. Heuclin, B. H. Hicks, C. I. Taylor, S. K. Vij, S. Pek, R. F. Knopf, J. C. Floyd, S. S. Fajans, T. D. R. Hockaday, J. M. Hockaday, J. I. Mann, R. C. Turner, A. J. Honour, Y. Ikeda, S. Saito, Y. Matsuura, N. Obayashi, Y. Morimoto, T. Sano, M. Abe, R. Jacouot, J. M. Felix, C. Legrele, M. -Th. Sutter-Dub, B. Ch. J. Sutter, L. Kammerer, J. Fehér, J. Lévai, R. Dénes, M. Stützel, I. Balázsi, I. Láng, L. Littmann, C. Karakash, F. Assimacopoulos, N. Katsilambros, G. Papadopoulos, D. Varonos, G. Daikos, H. Keen, R. J. Jarrett, J. H. Fuller, N. H. K. Kiesselbach, W. Puls, U. Keup, Ryuichi Kikkawa, D. Duvillard, M. Ravazzola, W. Stauffacher, J. Köbberling, R. Kattermann, J. Kobberling, W. Creutzfeldt, Eva M. Kohner, A. M. Hamilton, G. F. Joplin, R. K. Blach, T. R. Fraser, H. J. Kolb, L. Weiss, O. H. Wieland, A. Korn, W. Waldhäusl, J. Bonelli, D. Magometsohnigg, G. Hitzenberger, Robert C. Kramp, G. J. Kremer, W. Atzpodien, B. Schnellbacher, B. Krug, P. Mialhe, R. Gross, R. Landgraf, M. Landgraf-Leurs, M. Klingenburg, I. Melamed, R. Hörl, István Láng Jun, László Littmann, Mária Stützel, Imre Balázsi, Derek R. Langslow, Keith D. Buchanan, Barry M. Freeman, Meir Berezin, I. Mincu, C. Dumitrescu, C. Ionescu-Tirgoviste, N. Mihalache, D. Boboia, J. Stanescu, E. Ghise-Beer, St. Georgescu, I. Bruckner, I. Popa, M. Muggeo, A. Tiengo, D. Padovan, M. Molinari, Walter A. Müller, Geoffrey W. G. Sharp
Publikováno v:
Diabetologia. 10:357-400