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Akademický článek

Clinical Outcome in Patients With Intracerebral Hemorrhage Stratified by Type of Antithrombotic Therapy

Autor: Merih Irem Baharoglu, Jonathan M. Coutinho, Henk A. Marquering, Charles B. Majoie, Yvo B. Roos

Publikováno v: Frontiers in Neurology, Vol 12 (2021)

Background: Antithrombotic therapy influences clinical outcome after spontaneous intracerebral hemorrhage (ICH). However, evidence on the effect of different antithrombotic therapies on outcome and a comparison between different therapies is scarce,

Externí odkaz: https://doaj.org/article/5218097e84624da09d3845dfa6c99407

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Akademický článek

Aging increases senescence, calcium signaling, and extracellular matrix deposition in human airway smooth muscle.

Autor: Sarah A Wicher, Benjamin B Roos, Jacob J Teske, Yun Hua Fang, Christina Pabelick, Y S Prakash

Publikováno v: PLoS ONE, Vol 16, Iss 7, p e0254710 (2021)

Lung function declines as people age and their lungs become stiffer. With an increasing elderly population, understanding mechanisms that contribute to these structural and functional changes in the aging lung is important. Part of the aging process

Externí odkaz: https://doaj.org/article/9ed70d7ed6a54bfd8c84a97a7475e3f6

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Noncovalent Stabilization of Radical Intermediates in the Enantioselective Hydroamination of Alkenes with Sulfonamides

Autor: Eve Y. Xu, Jacob Werth, Casey B. Roos, Andrew J. Bendelsmith, Matthew S. Sigman, Robert R. Knowles

Publikováno v: Journal of the American Chemical Society. 144:18948-18958

Noncovalent interactions (NCIs) are critical elements of molecular recognition in a wide variety of chemical contexts. While NCIs have been studied extensively for closed-shell molecules and ions, very little is understood about the structures and pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0770cdf289d16b5bbbe919fada25332
https://doi.org/10.1021/jacs.2c07099

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Functional α7 nicotinic receptors in human airway smooth muscle increase intracellular calcium concentration and contractility in asthmatics

Autor: Latifa Khalfaoui, Nuriya Mukhtasimova, Brian Kelley, Natalya Wells, Jacob J. Teske, Benjamin B. Roos, Niyati A. Borkar, Emily Y. Zhang, Steven M. Sine, Y. S. Prakash, Christina M. Pabelick

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology.

Although nicotinic acetylcholine receptors (nAChRs) are commonly associated with neurons in the brain and periphery, recent data indicate they are also expressed in non-neuronal tissues. We recently found the alpha7 (α7nAChR) subunit is highly expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0aa5cf1558bb198045c8690192847e0
https://doi.org/10.1152/ajplung.00260.2022

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